OpenScience.ink

4 days ago • Journal of human hypertension

Cardiovascular frailty as a new type of frailtyCardiovascular frailty - an emerging frailty phenotype.

📖 Top 20% JournalArticle

4 days ago • Inflammopharmacology

Using nano-immunomodulators to influence immune signaling pathways in Alzheimer’s and Parkinson’s diseasesPharmacological modulation of cGAS-STING-NLRP3 signaling by nano-immunomodulators in Alzheimer and Parkinson disease.

📖 Top 20% JournalArticle

5 days ago • Signal transduction and targeted therapy

Hepassocin may slow liver aging and help liver repair by activating energy controlHepassocin prevents age-related liver senescence and facilitates liver regeneration by activating AMPK.

🥇 Top 1% JournalArticle

5 days ago • Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy

Imaging hydrogen sulfide-related oxidative imbalance in Parkinson’s disease models using near-infrared fluorescence and mass spectrometryCoupled NIR-II fluorescence and mass spectrometry imaging of H2S-associated redox dysregulation in Parkinsonian models.

Article

5 days ago • Journal of hazardous materials

Bisphenol A changes brown fat by causing cell death, fat buildup, and inflammationBisphenol A remodels brown adipose tissue via apoptosis, whitening, and inflammatory stress.

🥉 Top 5% JournalArticle

5 days ago • Mechanisms of ageing and development

Biological Age from DNA Methylation and Its Relationship to Reproductive History: Review and Combined AnalysisBiological age measured by DNA methylation clocks and reproductive history: Systematic review and meta-analysis.

Article

5 days ago • Experimental gerontology

GLP-1 receptor drugs, aging-related gene changes, and possible lifespan extension with medicineGLP-1 receptor agonists, epigenetic aging, and the prospect of pharmacological healthspan extension.

Article

5 days ago • Orthopadie (Heidelberg, Germany)

Biological Age in Orthopedics: Why It Matters, How to Measure It, and Clinical Advice[Biological age in orthopedics : Importance, assessment, and clinical recommendations].

English Abstract

5 days ago • Medical gas research

Nitric oxide signals and removal of damaged mitochondria in Parkinson's disease: possible links to brain protection from aerobic exerciseNitric oxide signaling and mitophagy in Parkinson's disease: implications for aerobic exercise-related neuroprotection.

📖 Top 30% JournalArticle

5 days ago • Seminars in nephrology

Kidney Injury Molecule: A Marker and Its Other RolesKidney Injury Molecule: a Biomarker and much more.

📖 Top 20% JournalArticle

5 days ago • Experimental physiology

Removing aging heart cells improves age-related heart changes in miceClearance of p16-positive cardiac cells improves age-related cardiac remodeling in mice.

Fulltext (Open License)Article

5 days ago • Materials today. Bio

A cell membrane-covered DNA nanoplatform for reshaping cartilage and joint lining interaction in osteoarthritisA biomimetic chondrocyte membrane-camouflaged tFNA nanoplatform for reprogramming the cartilage-synovium axis in osteoarthritis.

🥉 Top 5% JournalArticle

5 days ago • Methods in molecular biology (Clifton, N.J.)

Features of Aging-Related Secretions in Natural and Lab-Grown Skin Cells Using Multiple TestsCharacterization of the Senescence-Associated Secretory Phenotype in Primary and Induced Pluripotent Stem Cell-Derived Skin Cells via Multiplex Assays.

📖 Top 50% JournalArticle

5 days ago • Materials today. Bio

Relieving nerve pain by using tiny particles that deliver working mitochondria and a mitochondria-cleanup booster to reshape cell energy centersMitochondrial remodeling by extracellular vesicles co-delivering functional mitochondria and a mitophagy inducer for neuropathic pain relief.

🥉 Top 5% JournalArticle

5 days ago • Mechanisms of ageing and development

Loss of Accurate Calcium Signaling with Aging Linked to Mitochondrial Problems, Cell Aging, and Decline in Thinking and MovementLoss of Ca2+ Signaling Fidelity During Aging: Mitochondrial Dysfunction, Senescence, and Cognitive-Motor Decline.

Article

5 days ago • Acta biochimica et biophysica Sinica

piR-45962 increases self-destructive cell death in aged heart injury by affecting a specific cell signaling pathwaypiR-45962 exacerbates autophagic apoptosis in aged myocardial ischemia-reperfusion injury through modulation of the HNRNPH1/GATA5 signaling axis.

📖 Top 20% JournalArticle

5 days ago • Pharmacological research

NMN May Reduce Liver Damage Caused by LPS by Preventing Cell Death Through Blocking the cGAS-STING-ACSL4 PathwayNMN Mitigates LPS-Induced Liver Injury by Inhibiting Ferroptosis via Suppression of the cGAS-STING-ACSL4 Axis.

🥉 Top 5% JournalArticle

5 days ago • International urogynecology journal

Thrombospondin-1, a Stretch-Sensitive Protein, May Cause Aging in Support Cells Linked to Pelvic Organ ProlapseThrombospondin-1 as a Mechanosensitive Matrix Protein Driving Fibroblast Senescence: A Novel Pathogenic Target for Pelvic Organ Prolapse.

📖 Top 30% JournalArticle

6 days ago • Bone research

Bone aging as a process of damage at multiple levels and ways to reverse itBone aging: a paradigm of multiscale degeneration and targeted rejuvenation.

🥈 Top 2% JournalArticle

6 days ago • Zoological research

Low oxygen before birth causes egg cell damage from oxidative stress through the Sirt3/Sod2 pathway, which may be reduced by nicotinamide mononucleotideFetal hypoxia causes oocyte oxidative stress damage via the Sirt3/Sod2 pathway and can be alleviated by nicotinamide mononucleotide.

📖 Top 20% JournalArticle

1 week ago • Materials today. Bio

Nanoparticles with D-mannose for skin aging treatment by protecting a key anti-aging proteinDevelopment of nanoparticles loaded with D-mannose for topical treatment to alleviate skin aging via rescuing SIRT1 from degradation.

🥉 Top 5% JournalArticle

1 week ago • Neuroprotection (Chichester, England)

Using Antimicrobial Drugs to Protect the Brain: How They Work, Possible Benefits, and ChallengesRepurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges.

📖 Top 50% JournalArticle

1 week ago • Autophagy reports

A new VPS16 gene change blocks cell recycling and causes early-onset DYT-VPS16 movement disorderA de novo VPS16 missense variant blocks autophagic flux and extends DYT-VPS16 into infancy.

Article

1 week ago • Metabolic brain disease

Aldometanib boosts energy regulation to improve metabolism and thinking in aging miceAMPK activation by Aldometanib from Bigujing improves metabolic and cognitive dysfunction in aging mice.

📖 Top 20% JournalArticle

1 week ago • Archives of gerontology and geriatrics

Faster biological aging and problems in multiple body functions linked to higher death risk in NHANES and CHARLS studiesBiological age acceleration and multidomain functional impairment: Mortality associations and incremental value in NHANES and CHARLS.

Article

1 week ago • Metabolic brain disease

Dihydromyricetin improves memory problems in aging mice by helping cells clear harmful inflammation complexesDihydromyricetin ameliorates cognitive dysfunction in SAMP8 mice via autophagy-mediated degradation of the NLRP3 inflammasome.

📖 Top 20% JournalArticle

1 week ago • Materials today. Bio

Nano-sized carriers with high Salvianolic acid B improve osteoarthritis treatment by targeting damaged cell partsThe mitophagy targeted nano-assemblies with high Salvianolic acid B -loading sufficiently enhances osteoarthritis therapy.

🥉 Top 5% JournalArticle

1 week ago • Metabolic brain disease

How Obesity May Cause Blood-Brain Barrier Problems: Underlying Processes and Possible TreatmentsMolecular mechanisms of blood-brain barrier dysfunction caused by obesity: pathophysiological understandings and treatment targets.

📖 Top 20% JournalArticle

1 week ago • Chemico-biological interactions

Neuroglobin helps control cell cleanup and prevent cell damage in brain development harmed by sevoflurane by boosting YTHDF3Neuroglobin positively regulates YTHDF3 to restore mitophagy and suppress ferroptosis in sevoflurane-induced developmental neurotoxicity.

📖 Top 20% JournalArticle

1 week ago • Progress in neuro-psychopharmacology & biological psychiatry

Resveratrol may improve age-related memory decline by activating cell repair and energy networks that support brain growth and cleanupResveratrol engages SIRT1/AMPK networks to restore BDNF signaling, autophagy, and mitochondrial function in age-related cognitive decline: A geroscience perspective.

Article

← prevpage 3 of 16next →

Latest Longevity & Aging Research Papers