Latest Longevity & Aging Research Papers | Page 3

4 days ago • Ageing research reviews

How Ageing Affects the Lymphatic System and Its Impact on Immunity, Brain Health, and TreatmentsAgeing and the lymphatic system: implications for immunity, brain health, and possible therapeutic interventions

🥈 Top 2% JournalArticle

4 days ago • International immunopharmacology

Bergapten may slow osteoarthritis by boosting cell cleanup and reducing cell death through a key cell growth pathwayBergapten ameliorates osteoarthritis progression by inhibiting the PI3K/AKT/mTOR pathway to activate mitophagy and suppress pyroptosis

Article

4 days ago • Ageing research reviews

Aging of Blood Vessel Lining Cells Linked to Mitochondria ProblemsEndothelial Cell Senescence and Mitochondrial Dysfunction in Vascular Ageing

🥈 Top 2% JournalArticle

5 days ago • Neuromolecular medicine

Brain Aging and How SIRT1 Activators May Protect the Brain: Mechanisms and Treatment PossibilitiesSIRT1 Activators as Geroprotective Agents in Brain Aging: Mechanisms and Therapeutic Potential

📖 Top 20% JournalFulltext (Open License)Article

5 days ago • Neurochemistry international

Blocking ESCRT-III triggers alternative ways cells break down and release proteinsInhibition of ESCRT-III activates alternative pathways for protein degradation and secretion

Article

5 days ago • NPJ Parkinson's disease

Parkinson's Disease Linked to DNAJC6 Gene: Problems in Cellular Waste Processing and New Roles for Brain Support CellsDNAJC6 Parkinson’s disease: Endolysosomal dysfunction and emerging roles for oligodendrocytes

🥉 Top 5% JournalArticle

5 days ago • Bioorganic & medicinal chemistry

Design, creation, and testing of benzimidazole carbamide compounds as possible triggers of cell self-cleaningDesign, synthesis and biological evaluation of benzimidazole carbamide derivatives – potential autophagy inducers

📖 Top 50% JournalArticle

5 days ago • Scientific reports

Reduced cell cleanup caused by Wdfy3 loss shows early brain disease signs in miceWdfy3-dependent autophagy impairment recapitulates presymptomatic neurodegenerative signatures in mice

📖 Top 20% JournalArticle

5 days ago • The journal of nutrition, health & aging

Faster body aging and brain changes that connect air pollution to dementia riskAccelerated biological aging and brain structural alterations linking air pollution to dementia risk: a prospective cohort study

Article

5 days ago • Ageing research reviews

Blood Vessel Aging as a Key Cause of Multiple Health ProblemsVascular aging: A central driver of multimorbidity

🥈 Top 2% JournalArticle

5 days ago • Journal of ethnopharmacology

Gene analysis shows how Shenxian Zhou may help prevent age-related memory declineTranscriptomic analysis reveals the critical role and mechanisms of Shenxian zhou in preventing age-related cognitive impairment

📖 Top 20% JournalArticle

5 days ago • Brain research bulletin

How Non-Coding RNA May Influence Cell Cleanup Processes in Alzheimer's DiseaseThe role of non-coding RNA-mediated autophagy in Alzheimer’s disease

📖 Top 20% JournalArticle

6 days ago • npj aging

Biological age measured from images of many organs is linked to risk of death and aging-related health problemsImaging-derived biological age across multiple organs links to mortality and aging-related health outcomes

🥉 Top 5% JournalFulltext (Open License)Article

6 days ago • Science advances

Longer life from lower IGF-1 signals may depend on how stable mitochondrial DNA isThe longevity effects of reduced IGF-1 signaling depend on the stability of the mitochondrial genome

🥈 Top 2% JournalArticle

6 days ago • Journal of cellular and molecular medicine

Using Natural Compounds to Prevent Cell Damage Linked to Bone and Muscle Diseases: An Updated ReviewTargeting Ferroptosis With Natural Products for the Treatment of Skeletal System Disease: An Updated Review

📖 Top 20% JournalFulltext (Open License)Article

6 days ago • 3 Biotech

Gandouling may protect the liver from scarring in Wilson disease through a specific RNA pathwayGandouling protects against hepatic fibrosis in Wilson disease through the lncRNA-SNHG7/miR-29b/DNMT3A pathway

📖 Top 30% JournalFulltext (Open License)Article

6 days ago • Molecular ecology

DNA Methylation Patterns Across the Genome Predict Age in Zebra Sharks and Offer Clues About How Aging Evolved in VertebratesGenome‐Wide DNA Methylation Patterns Predict Age in the Zebra Shark (Stegostoma tigrinum) and Provide Insight Into the Evolution of Vertebrate Aging

🎖️ Top 10% JournalFulltext (Open License)Article

6 days ago • Frontiers in aging neuroscience

Using very fast MRI to estimate brain age in a clinic for thinking problemsUltra-fast MRI for brain-age prediction in a real-world cognitive disorders clinic

🎖️ Top 10% JournalFulltext (Open License)Article

6 days ago • ChemMedChem

Review of the Medicinal Chemistry of the NEET Protein FamilyMedicinal Chemistry Review of the NEET Protein Family

📖 Top 30% JournalArticle

6 days ago • bioRxiv : the preprint server for biology

Activating the protective renin-angiotensin system improves energy production and reduces stress in cells with Complex III deficiencyActivation of the protective arm of renin-angiotensin system enhances mitochondrial turnover improving respiration and decreasing integrated stress response in a human Complex III deficiency model.

Preprint

6 days ago • medRxiv : the preprint server for health sciences

FDA-Approved Tenofovir Alafenamide Treatment May Lower Biological Age in Healthy Adults by Targeting Mobile DNA ElementsAn FDA-Approved Tenofovir Alafenamide-Based Antiretroviral Therapy Reduces Biological Age in Healthy Adults: First Human Proof-of-Concept for Retrotransposon-Targeted Gerotherapeutics

Preprint

6 days ago • Cell chemical biology

A nature-inspired nanoparticle system for breaking down multiple proteins using the cell's recycling pathwayA nature-inspired nanoplatform for multi-protein targeted degradation via the autophagy-lysosome pathway

🥉 Top 5% JournalArticle

6 days ago • ACS chemical biology

Compounds that Boost Defective NPC1 Protein and Help Remove Cholesterol in Cells from Niemann-Pick Type C PatientsDiscovery of Autophagy Modulators that Increase I1061T NPC1 Expression and Promote Cholesterol Efflux in Niemann-Pick Type C Patient-Derived Fibroblasts

🎖️ Top 10% JournalArticle

6 days ago • medRxiv : the preprint server for health sciences

Using deep learning to predict health risks and death from the body's level of aging cellsA deep-learning based biomarker of systemic cellular senescence burden to predict mortality and health outcomes

Preprint

6 days ago • medRxiv : the preprint server for health sciences

Adjusting biological age measures for specific body areas in a long-living population using DNA methylationAging Out of the Blue: Region-Specific Epigenetic Clock Calibration for a Blue Zone with the DNAm SuperLearner

Preprint

6 days ago • Oncology research

Signs of Oxidative Stress in Bone Marrow Stem Cells from Untreated Advanced Breast CancerOxidative Stress Footprints in Bone Marrow Mesenchymal Stem Cells from Untreated Advanced Breast Cancer

📖 Top 20% JournalArticle

6 days ago • Biochemical and biophysical research communications

Resveratrol and nanodiamonds’ effects on cell protection and DNA damage in house cricketsEffects of resveratrol and nanodiamonds on sirtuin activity, oxidative stress and DNA damage in Acheta domesticus

📖 Top 30% JournalArticle

6 days ago • bioRxiv : the preprint server for biology

Problems in a new connection between cell cleanup and energy parts may contribute to cell recycling failure and brain damage in tau-related diseasesDysregulation of a novel autophagosome-mitochondria contact contributes to autophagy dysfunction and neurodegeneration in tauopathy

Preprint

6 days ago • Mitochondrion

Higher levels of miR-455-3p may increase removal of damaged mitochondria and support nerve and energy proteins in Alzheimer's diseaseOverexpression of miR-455-3p enhances mitophagy, synaptic and mitochondrial proteins in Alzheimer’s disease

📖 Top 20% JournalArticle

6 days ago • Nature aging

Using Space Travel as a Model for Faster AgingThe case for space as a model of accelerated aging

🥇 Top 1% JournalArticle

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