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1 week ago • International immunopharmacology

Stopping a specific cell signaling process prevents immune cell aging and improves bacteria-killing during sepsis-related immune weaknessTargeting the AKT2-NAMPT phosphorylation axis prevents macrophage senescence to enhance bactericidal activity in septic immunosuppression.

Article

1 week ago • International journal of general medicine

Changes in Bone Marrow Immune and Metabolic Function in Osteoporosis: From Overall Risk to Targeted TreatmentBone Marrow Immunometabolic Remodeling in Osteoporosis: From Systemic Risk Factors to Precision Intervention.

Article

1 week ago • Experimental gerontology

Changes in Biological Aging and DNA Methylation Patterns in Anderson-Fabry DiseaseEpigenetic aging and autosomal methylation remodeling in Anderson-Fabry disease.

Article

1 week ago • Cureus

Frailty in Heart and Kidney Care: Older Adults and the 2026 European Heart GuidelinesFrailty in Cardiorenal Care: A Geriatric Perspective on the 2026 European Society of Cardiology Guidelines.

Editorial

1 week ago • International journal of radiation biology

Resveratrol reduces radiation damage and oxidative stress in rats, possibly through activating the body's antioxidant defense systemResveratrol mitigates radiation-induced oxidative stress and tissue injury in rats: potential involvement of the Nrf2-ARE antioxidant pathway.

Article

1 week ago • Molecular and cellular biochemistry

Nanoplastics may disrupt cell skeleton and transport, linked to cell aging and declineNanoplastics as disruptors of microtubule dynamics and intracellular trafficking: implications for cellular senescence and ageing.

Article

1 week ago • Biochimie

Selenium's Role in Aging and LifespanSelenium in Aging and Longevity.

Article

1 week ago • Nature reviews. Drug discovery

New treatments to build muscle and support healthy agingStrengthening muscle for healthy ageing: innovative treatments for sarcopenia.

Article

1 week ago • International archives of occupational and environmental health

Shift work linked to faster aging and higher death risk in US adultsShift work, accelerated biological aging and mortality risk in US adults: a national prospective cohort study.

Article

2 weeks ago • Biochimica et biophysica acta. Molecular basis of disease

How Circular RNAs and SIRT1 Control Gene Activity After Transcription and Their Links to Human DiseaseCircular RNAs and SIRT1 in post-transcriptional regulation and human disease.

Article

2 weeks ago • International journal of molecular medicine

Cell Death in Metabolic Syndrome: From How It Happens to Possible TreatmentsProgrammed cell death in metabolic syndrome: From molecular mechanisms to therapeutic strategies (Review).

Article

2 weeks ago • International journal of molecular medicine

How Cell Recycling Controls Immune Cell Survival by Managing Metabolism and a Combined Cell Death ProcessAutophagy determines the fate of immune cells by regulating metabolic remodeling and PANoptosis (Review).

Article

2 weeks ago • Reproduction (Cambridge, England)

Changing Fertility Timing in Women with Reduced Egg SupplyBeyond the Clock: Reprogramming Fertility in Diminished Ovarian Reserve.

Article

2 weeks ago • FASEB journal : official publication of the Federation of American Societies for Experimental Biology

ASIV may reduce kidney cell damage from cisplatin by boosting mitochondrial renewal and cleanup through the ADRA1A/AMPK/FOXO3A pathwayASIV Attenuates Cisplatin-Induced Proximal Tubular Injury by Enhancing Mitochondrial Biogenesis and Mitophagy Through the ADRA1A/AMPK/FOXO3A Pathway.

Article

2 weeks ago • microPublication biology

Deguelin may increase lifespan and health in C. elegans through the fmo-4 geneErratum: Corrigendum: Deguelin promotes longevity and healthspan through C. elegans fmo-4.

Published Erratum

2 weeks ago • Experimental gerontology

Article

2 weeks ago • Histochemistry and cell biology

Higher DNA 5-hydroxymethylation helps stem cells become cartilage cells by lowering hTERT through TET enzymesElevated DNA 5-hydroxymethylation promotes chondrocyte differentiation via TET-mediated epigenetic downregulation of hTERT in human mesenchymal stem cells.

Article

2 weeks ago • Proceedings of the National Academy of Sciences of the United States of America

A Hox-controlled process keeps autophagy genes turned off near the cell nucleusA Hox-dependent anchoring mechanism mediates transcriptional repression of autophagy-related genes at the nuclear periphery.

Article

2 weeks ago • International immunopharmacology

Diosgenin glucoside may support platelet production by promoting cell recycling through the AMPK/mTOR/ULK1 pathwayThe role and mechanism of diosgenin glucoside in modulating megakaryopoiesis through promotion of autophagy via the AMPK/mTOR/ULK1 signaling pathway.

Article

2 weeks ago • Neurochemistry international

Amyloid-beta linked to overactive CaMKII and problems in cell waste recycling and damaged mitochondria removalAβ-induced CaMKII hyperactivation is associated with impaired lysosomal maturation and mitophagy.

Article

2 weeks ago • The journals of gerontology. Series A, Biological sciences and medical sciences

Biological Aging Measures and Long Healthy Thinking in Older WomenEpigenetic Clocks of Biological Aging and Cognitively Healthy Longevity: The Women's Health Initiative Memory Study.

Article

2 weeks ago • Cardiovascular drugs and therapy

Empagliflozin may reduce artery plaque by boosting cell cleanup in blood vessel liningEmpagliflozin Improves Atherosclerosis by Promoting Mitophagy in Endothelial Cells.

Article

2 weeks ago • Acta physiologica (Oxford, England)

Increasing AS160 Protects Insulin-Producing Cells in High Blood Sugar Mice by Working with HSPA8 to Control Mitochondrial CleanupAS160 Overexpression Protects Against β-Cell Failure in Hyperglycemic Mice by Interacting With HSPA8 to Regulate Mitophagy.

Article

2 weeks ago • Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion

Biological aging clocks as markers of human aging: their basis, design, and population impactBiological aging clocks as biomarkers of human aging: Biological basis, methodological design, and epidemiological implications.

Article

2 weeks ago • International journal of general medicine

How p38 MAPK Signaling May Contribute to Heart Damage from DoxorubicinMechanisms and the Role of p38 MAPK Signaling in Doxorubicin-Induced Cardiotoxicity: A Review.

Article

2 weeks ago • Phytotherapy research : PTR

Using Natural Supplements in Heart Failure, Irregular Heartbeats, and Related Heart ConditionsIntegrative Approaches in Cardiovascular Disease: The Role of Nutraceuticals in Heart Failure, Atrial Fibrillation, and Related Conditions.

Article

3 weeks ago • Chinese medical journal

Materials that change metabolism to treat bone and muscle disordersBiomaterials for metabolic reprogramming in skeletal disorders.

Article

3 weeks ago • The journals of gerontology. Series A, Biological sciences and medical sciences

Metabolite profiles linked to telomere length, aging traits, and lifestyle in older Chinese adultsMetabolomic Profiling of Telomere Length: Associations with Aging-related Phenotypes and Modifiable Lifestyle Factors in Chinese Older Adults.

Article

3 weeks ago • International journal of molecular medicine

New Insights into Sirtuin Proteins in Lung DiseasesAdvances in sirtuin research in lung diseases (Review).

Article

3 weeks ago • Life sciences

Genetic differences in kidney cells linked to kidney disease progression, cell damage, aging, and treatment optionsSomatic genomic mosaicism in chronic kidney disease progression: A graded appraisal of renal epithelial injury, cellular senescence, and therapeutic implications.

Article

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Longevity & Aging Research Papers