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3 weeks ago • Molecular biology reports

How GABARAPL2 and Alix control cell recycling and communication to maintain cell balanceGABARAPL2 and Alix mediate reciprocal regulation of autophagy and exosome pathways to facilitate cellular homeostasis.

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3 weeks ago • Biochemical and biophysical research communications

Creating a lasting human hair follicle skin cell line that can still produce hairGeneration of an immortalized human hair follicle keratinocyte cell line retaining trichogenic potential.

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3 weeks ago • Molecular biology reports

How mTOR and AMPK signals relate to placental problems and preeclampsia, and how metformin may helpThe mTOR/AMPK signaling axis in placental dysfunction and preeclampsia: mechanisms and therapeutic targeting with metformin.

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3 weeks ago • BMC nephrology

Kidney problems and their treatment in people with tuberous sclerosis complex in BrazilFeatures and management of kidney manifestations of tuberous sclerosis complex: a real-world study in a Brazilian patient cohort.

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3 weeks ago • Molecular biology reports

Advances in Understanding VDAC2's Role in Diseases Caused by Mitochondrial ProblemsResearch progress on VDAC2 in mitochondrial dysfunction-related diseases.

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3 weeks ago • Molecular biology reports

Changes in gene regulation in bone marrow stem cells of patients with acquired aplastic anemia studied by computer and lab experimentsEpigenomic dysregulation in the bone marrow mesenchymal stem cells of acquired aplastic anemia patients: An in silico and in vitro study.

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3 weeks ago • Journal of gynecology obstetrics and human reproduction

Tuberous sclerosis complex and its effects on reproduction: an overviewTuberous sclerosis complex and reproduction: a scoping review.

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3 weeks ago • Molecular biology reports

Nicotinamide mononucleotide may improve heart cell metabolism damaged by high sugar and fat by stabilizing energy use through SIRT1Nicotinamide mononucleotide ameliorates high glucose/high fat-induced cardiomyocyte metabolic dysfunction through SIRT1-mediated CPT1A stabilization.

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3 weeks ago • Molecular biology reports

Curcumin nanomicelle’s dose-dependent effects on cell recycling signals in rat testisDose-dependent effect of curcumin nanomicelle on autophagy signaling in testis; a study on normal Wistar rats.

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3 weeks ago • Human gene therapy

Gene Therapy Using hBAG3 Improves Symptoms in a Mouse Model of Hereditary Muscle Disease Caused by Valosin ProteinAAV.hBAG3 Gene Therapy Improves Phenotype in a Valosin Containing Protein Mouse Model of Hereditary Inclusion Body Myositis.

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3 weeks ago • Stem cell reviews and reports

How Mitochondrial Protein Tagging in Different Cell Types May Influence Stem Cell FateCell-Type-Specific Calibration of Mitochondrial Ubiquitination in Stem Cell Fate Decisions.

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3 weeks ago • Histology and histopathology

Henagliflozin may help kidney cells remove damaged mitochondria by activating energy sensors to slow diabetic kidney diseaseHenagliflozin promotes mitophagy in renal tubular cells by activating AMPK/ULK1 to alleviate the progression of diabetic kidney disease.

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3 weeks ago • Cellular signalling

NSUN2 links sugar and one-carbon metabolism to mTORC1 signaling controlled by Rag GTPasesNSUN2 integrates glucose and one‑carbon metabolism upstream of Rag GTPase-dependent mTORC1 signaling.

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4 weeks ago • Drug development research

Targeting Cell Recycling Processes in Alzheimer's Disease: The Role of Energy Control Pathways and Reusing Existing DrugsTargeting Autophagy in Alzheimer's Disease: Role of the AMPK/mTOR Pathway and Drug Repurposing.

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4 weeks ago • Naunyn-Schmiedeberg's archives of pharmacology

How fisetin may affect brain diseases by controlling inflammation, cell stress, and cell cleanup processesPharmacological mechanisms of fisetin in neurodegenerative disorders: regulation of neuroinflammatory, oxidative, and autophagic pathways.

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4 weeks ago • Molecular biology reports

How baicalein may help Parkinson's by reducing brain inflammation and cell death while boosting nerve growth and connectionsMechanistic insights into anti-parkinson effect of baicalein: from neuroinflammation and cell death to neurogenesis and synaptic plasticity.

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4 weeks ago • BMC pulmonary medicine

Differences in genetic testing, screening, team care, and lung transplant treatment for inherited lung disease across locations and workplacesGeographical, institutional and workplace variability in genetic evaluation, screening practices, multidisciplinary care, and lung transplantation management for familial interstitial lung disease.

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4 weeks ago • Odontology

How Changes in Gene Regulation Affect Gum Aging, Gum Disease, and Possible TreatmentsEpigenetic mechanisms of gingival aging: biological basis, periodontal implications, and therapeutic perspectives.

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4 weeks ago • The Journal of steroid biochemistry and molecular biology

β-sitosterol and new neuroprotection approaches targeting multiple systems and the gut-brain connection in neurodegenerative diseasesβ-sitosterol and next-generation neuroprotection for multi-target strategies and the gut-brain axis in neurodegenerative diseases.

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4 weeks ago • Metabolic brain disease

Transthyretin's protective role in Parkinson's disease and brain degenerationTransthyretin at the crossroads of neurodegeneration: a silent guardian in Parkinson's disease.

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4 weeks ago • Inflammation

Cellular Cleanup of Damaged Mitochondria in Fatty Liver Disease Linked to Metabolism: How It Works, Controls, and Treatment PossibilitiesMitophagy in Metabolic Dysfunction-Associated Fatty Liver Disease: Mechanisms, Regulatory Networks, and Therapeutic Perspectives.

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1 month ago • Journal of cardiology

Mitochondrial Cleanup in Heart and Blood Vessel Disease: Understanding How It Works and Possible TreatmentsMitophagy in Cardiovascular Disease: From Mechanistic Insights to Therapeutic Horizons.

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1 month ago • Current pharmaceutical design

Resveratrol's potential to reduce inflammation by affecting the NLRP3 immune responseResveratrol and the NLRP3 Inflammasome: Unlocking the Anti-inflammatory Potential of a Natural Compound.

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1 month ago • Brain research bulletin

Research trends and biological roles of sirtuins in Alzheimer's diseaseGlobal Research Trends and Mechanistic Insights of Sirtuins in Alzheimer's Disease: A Bibliometric and Translational Review.

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1 month ago • Biochemical genetics

How Exercise May Influence Gene Control and RNA in Muscle Aging and LossThe Role of Exercise in Regulating Histone Modifications and Non-coding RNAs in Muscle Aging and Sarcopenia.

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1 week ago • Nature

Energy use in cells and gene regulation together influence the aging-related secretionsMitochondrial metabolism and epigenetic crosstalk drive SASP.

Article

2 days ago • Clinical and experimental reproductive medicine

Nicotinamide mononucleotide's potential to support ovarian health based on preclinical studiesThe impact of nicotinamide mononucleotide on ovarian health: A comprehensive literature review of preclinical evidence and therapeutic potential.

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5 days ago • Medicine

How Cell Aging Relates to Sepsis and Copper-Induced Cell Death: A Machine Learning AnalysisThe role of cellular senescence in sepsis and its mechanism in copper death: An analysis based on machine learning.

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2 weeks ago • Epigenomics

Using epigenetic markers to guide chronic pain treatment and predict health outcomesClinical applications of epigenetic signatures in chronic pain management and health outcome prediction.

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2 weeks ago • Zeitschrift fur Gerontologie und Geriatrie

Miscommunication between cells in aging and long-term inflammation[Misdirected intercellular communication in aging and chronic inflammation].

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Longevity & Aging Research Papers