OpenScience.ink

1 week ago • Immunological investigations

How the ATG14-SIRT1 Interaction May Influence Inflammation and Immune Response in Sudden Lung InjuryThe ATG14-SIRT1 Axis Modulates NF-Κb Pathway Activation and Inflammatory Responses in Acute Lung Injury.

📖 Top 30% Journal

1 week ago • Fitoterapia

2-Amino-5-hydroxyhexanoic acid helps prevent muscle loss in diabetes by maintaining protein balance2-Amino-5-hydroxyhexanoic acid mitigates diabetes-induced skeletal muscle atrophy by preserving protein homeostasis.

📖 Top 50% Journal

1 week ago • Cellular signalling

Mitochondrial Problems in Disc Degeneration Linked to Oxidative Stress, Cell Changes, and Tissue BreakdownMitochondrial dysfunction in intervertebral disc degeneration: Linking oxidative stress, altered cell fate, and Matrix degeneration.

📖 Top 20% Journal

1 week ago • Cardiovascular toxicology

METTL1 enzyme increases USF2 to speed up septic heart damage by blocking a protective cell cleanup processMethyltransferase METTL1 Upregulates USF2 in a m7G-Dependent Manner to Accelerate Septic Cardiomyopathy by Inactivating PINK1/Parkin-Mediated Mitophagy.

📖 Top 30% Journal

2 weeks ago • Functional & integrative genomics

ANGPTL4 as a diagnostic marker linked to placental aging in gestational diabetesANGPTL4 in gestational diabetes: a diagnostic biomarker linked to placental senescence.

📖 Top 30% Journal

2 weeks ago • Molecular biology reports

Stress between cell energy centers and their partners in asthmaER-mitochondria contact sites and organelle stress in asthma.

📖 Top 30% Journal

2 weeks ago • The Journal of steroid biochemistry and molecular biology

Estrogen’s role in controlling key inflammation and repair systems to protect the brain during aging and neurodegenerationEstrogen's master switch: NFκB-NLRP3, SIRT1-HMGB1, and TLR4 triad tamed for brain rescue in ageing and neurodegeneration.

📖 Top 30% Journal

2 weeks ago • Molecular biology reports

circPVT1 helps protect hearing cells from aging caused by D-galactoseProtective effects of circPVT1 against D-galactose-induced senescence in HEI-OC1 auditory cells.

📖 Top 30% Journal

2 weeks ago • Metabolic brain disease

Using neural networks to study cell death and treatment options in early-onset Alzheimer's diseaseNeural network-enhanced investigation of ferroptosis and druggability in early-onset alzheimer's disease.

📖 Top 20% Journal

2 weeks ago • Molecular biology reports

Nicotinamide mononucleotide may reduce testicular cell death and improve mitochondrial function in rats treated with doxorubicinInvestigating the effects of nicotinamide mononucleotide administration on testicular apoptosis, and mitochondrial function in doxorubicin-treated rats.

📖 Top 30% Journal

2 weeks ago • Molecular biology reports

How Exercise May Influence a Key Protein That Affects Joint Health in OsteoarthritisThe role of exercise in MFN2 regulation in osteoarthritis.

📖 Top 30% Journal

2 weeks ago • Cellular signalling

How the USP5-MATN3 pathway helps protect spine disc cells from aging and degenerationThe USP5-MATN3 axis in nucleus pulposus cell senescence: A Deubiquitination mechanism protecting against intervertebral disc degeneration.

📖 Top 20% Journal

2 weeks ago • Molecular medicine reports

How Key Gene Control Networks Linked to Super-Enhancers May Influence AgingFrom cell to disease: Regulatory networks and mechanisms of super‑enhancers in aging (Review).

📖 Top 30% Journal

2 weeks ago • Neuromolecular medicine

STAT6 Controls Cell Cleanup to Affect Brain Immune Cell Aging in Thinking Problems from Small Blood Vessel DiseaseSTAT6 Targets the Autophagy Pathway to Regulate Microglial Senescence in Cognitive Impairment Caused by Cerebral Small-Vessel Disease.

📖 Top 20% Journal

2 weeks ago • Aging

Including Healthspan Improvement Plans in the Italian National Health ServiceTowards integration of healthspan strategies into the Italian National Health Service.

📖 Top 20% Journal

2 weeks ago • Immunologic research

How two key cell signaling pathways interact in multiple sclerosis and their potential for treatmentDecoding the PI3K/Akt/mTOR-JAK/STAT signaling axis in multiple sclerosis: mechanistic crosstalk and therapeutic opportunities.

📖 Top 20% Journal

2 weeks ago • Discover oncology

Using data analysis and machine learning to find potential cell recycling targets for treating prostate cancerIntegrated bibliometric and machine learning analyses identify candidate autophagy related therapeutic targets for prostate cancer.

📖 Top 20% Journal

2 weeks ago • Molecular biology reports

Different gene and protein patterns related to energy use, inflammation, and protein maintenance in the liver and brain of rats with Parkinson’s-like damage from rotenoneIdentification of divergent organ-specific gene and protein expression signatures for mitochondrial function, inflammatory response, and proteostasis in the liver and brain in the rotenone-induced rat model of Parkinson's disease.

📖 Top 30% Journal

2 weeks ago • Function (Oxford, England)

Constant Activation of Muscle Growth Pathway Raises Inflammation but Does Not Hurt Blood Sugar ControlConstitutive mTORC1 Activation in Skeletal Muscle Increases Inflammation but is not Sufficient to Impair Glucose Tolerance.

📖 Top 20% Journal

2 weeks ago • Hormones (Athens, Greece)

Molecular profiles of fats and proteins in MASLD to guide targeted treatmentsLipidomics and proteomics in MASLD: reading the molecular script toward precision therapeutics.

📖 Top 30% Journal

2 weeks ago • Journal of molecular histology

Testosterone propionate supports cell cleanup and energy factory health by controlling key cell recycling signals in liver scarringTestosterone propionate maintains autophagic flux and mitochondrial integrity via regulation of the LC3B/p62/Beclin-1/mTOR axis in induced liver fibrosis.

📖 Top 30% Journal

2 weeks ago • Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

Long-Term Infection and Heart Aging: New Insights into Infection-Linked Heart Muscle DiseaseChronic Infection and Cardiac Aging: a New Perspective on Pathogen-Associated Cardiomyopathy.

📖 Top 30% Journal

2 weeks ago • Metabolic brain disease

How Exercise May Protect the Brain in Alzheimer's Disease Through the CTSS PathwayThe Exercise-CTSS-AD Axis: a novel framework for understanding exercise-induced neuroprotection in Alzheimer's disease.

📖 Top 20% Journal

3 weeks ago • Molecular biology of the cell

Removal and release of alpha-synuclein through RTN3L-controlled cell cleanup processClearance and secretion of α-synuclein by RTN3L-mediated endoplasmic reticulum autophagy.

📖 Top 20% Journal

3 weeks ago • Tissue & cell

How METTL14 and YTHDF1 help restore cell cleaning to reduce tuberculosis bacteria survivalMETTL14/YTHDF1 axis restores ULK1-mediated autophagic flux to suppress Mycobacterium tuberculosis survival.

📖 Top 30% Journal

3 weeks ago • Cardiovascular toxicology

Welding Metals Linked to Heart Disease Risk in Male Welders Through Faster Biological AgingAssociations Between Welding-Related Metals and Atherosclerotic Cardiovascular Disease Risk in Male Welders: The Mediating Role of Accelerated Biological Aging.

📖 Top 30% Journal

3 weeks ago • Biochemical and biophysical research communications

Ergothioneine reduces age-related weakening of daily body rhythmsErgothioneine attenuates age-related declines in circadian rhythmicity.

📖 Top 30% Journal

3 weeks ago • International urology and nephrology

A global analysis of aging cells in kidney diseases and new treatment directionsCellular senescence in kidney diseases: a bibliometric analysis of global trends, knowledge bases, and emerging therapeutic frontiers.

📖 Top 50% Journal

3 weeks ago • JBRA assisted reproduction

Obesity and weight loss have different effects on cell recycling in mouse ovarian support cellsObesity and weight loss differentially regulate autophagy in mouse ovarian granulosa cells.

📖 Top 50% Journal

3 weeks ago • Journal of biomolecular structure & dynamics

Natural compounds that adjust a protein involved in heart function: a computer simulation studyAllosteric modulation of Drp1 by natural compounds for cardiac therapeutics: a molecular docking and dynamics study.

📖 Top 50% Journal

← prevpage 13 of 18next →

Longevity & Aging Research Papers