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1 month ago • Ageing research reviews

Aging of Bone Stem Cells: Causes, Effects on Bone Aging, and Possible TreatmentsAging of mesenchymal stem cells in bone aging: Mechanisms, impact, and therapeutic perspectives.

🥈 Top 2% Journal

1 month ago • Archives of biochemistry and biophysics

Reducing a Protein from Immune Cells May Ease Lung Scarring After Radiation by Slowing Cell Aging and InflammationTargeting CD8+ T Cell-Derived Granzyme K Alleviates Radiation-Induced Pulmonary Fibrosis by Attenuating Senescence and SASP.

📖 Top 20% Journal

1 month ago • Biogerontology

Emodin may reduce lung scarring after radiation by targeting cell aging through the mitochondrial DNA immune response pathwayEmodin alleviates radiation-induced pulmonary fibrosis by targeting cellular senescence via the mtDNA-cGAS-STING axis.

📖 Top 20% Journal

1 month ago • Molecular neurobiology

A Unified Cell-Death Process in the Nervous System Linked to Immune Activation and Long-Term Brain InflammationDissecting PANoptosis in the Nervous System: A Unified Cell-Death Mechanism Driving Neuroimmune Activation and Chronic Neuroinflammation.

🎖️ Top 10% Journal

1 month ago • Food research international (Ottawa, Ont.)

Butyrate from Lycium ruthenicum polysaccharide reduces chronic fatigue from sleep loss in mice by boosting brain immune cell cleanupWIPButyrate produced by the Lycium ruthenicum polysaccharide alleviated sleep deprivation-induced chronic fatigue syndrome in mice through promoting microglial autophagy.

🎖️ Top 10% Journal

1 month ago • Molecular neurobiology

Curcumin may reduce copper-related cell death by boosting cell cleanup through blocking a key growth signaling pathway in Parkinson's disease modelsCurcumin Attenuates Cuproptosis via Activating Autophagy Through Inhibition of the AKT/mTOR/P70S6K-Signaling Pathway in Parkinson's Disease Models.

🎖️ Top 10% Journal

yesterday • Toxicology in vitro : an international journal published in association with BIBRA

7,8-Dihydroxyflavone reduces DNA damage caused by etoposide in heart cells through a two-phase process involving p537,8-Dihydroxyflavone attenuates etoposide-induced genotoxicity in cardiomyocytes via a biphasic, p53-dependent mechanism.

📖 Top 30% JournalArticle

yesterday • Journal of molecular histology

How a growth factor-controlled cell cleanup process helps keep cartilage healthy and may influence osteoarthritisThe role of the HB-EGF-regulated EGFR-mitophagy axis in maintaining cartilage homeostasis and osteoarthritis.

📖 Top 30% JournalArticle

2 days ago • Molecular biology reports

Calreticulin's role in managing cell stress, protein balance, calcium levels, and immune cleanupCalreticulin as a stress-responsive integrator of ER proteostasis, calcium homeostasis, and immune clearance.

📖 Top 30% JournalArticle

2 days ago • Pharmacology

How NLRP3 inflammasome and cell cleanup processes work together in heart diseasesThe co-regulation of NLRP3 inflammasome and autophagy for cardiovascular diseases.

📖 Top 30% JournalArticle

3 days ago • Naunyn-Schmiedeberg's archives of pharmacology

Changes over time in drug strategies using natural and designed compounds to control cell recycling in brain diseasesPharmacological evolution of natural product-based and chemically engineered autophagy-modulating strategies in neurodegenerative diseases: a bibliometric mapping analysis (2006-2025).

📖 Top 30% JournalArticle

5 days ago • Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics

Metformin’s multiple roles in preventing and treating major eye diseases beyond blood sugar controlBeyond Glycemic Control: Metformin's Multi-Target Role in Preventing and Treating Major Ocular Pathologies.

📖 Top 50% JournalArticle

5 days ago • Biophysical chemistry

Using solid-state NMR to study protein clumping, phase changes, and droplet-like assembliesSolid-state NMR methods to investigate biomolecular condensates, protein phase transition, phase separation and coacervates.

📖 Top 30% JournalArticle

5 days ago • Molecular biology reports

How AMPK controls fat metabolism and its possible use in treatmentsMechanisms and therapeutic potential of AMPK signaling pathway in the regulation of lipid metabolism.

📖 Top 30% JournalArticle

6 days ago • Neuromolecular medicine

Controlling Brain and Nerve Inflammation After Spinal Cord Injury by Targeting the cGAS-STING Immune PathwayResearch Progress on Regulating Neuroinflammation After Spinal Cord Injury by Targeting the cGAS-STING Pathway.

📖 Top 20% JournalArticle

6 days ago • Cellular signalling

Short-term fasting and exercise together affect energy control in the memory area of healthy miceA combined stimulus of acute fasting and exercise modulates hippocampal mitochondrial quality control in healthy mice.

📖 Top 20% JournalArticle

1 week ago • Cellular signalling

Blocking the ETS1/DRP1 pathway may reduce disc degeneration by limiting excessive mitochondrial splittingInhibition of ETS1/DRP1 axis attenuates intervertebral disc degeneration by suppressing excessive mitochondrial fission.

📖 Top 20% JournalArticle

1 week ago • Bio-protocol

Live Imaging of Aging Cell Activity in Transparent KillifishIn Vivo Light-Sheet Imaging of Senescence Reporter Activity in a Transparent Killifish.

📖 Top 50% JournalArticle

1 week ago • Kidney & blood pressure research

Changes in Blood Vessel Lining Cells in Chronic Kidney Disease: Causes and Possible TreatmentsEndothelial-to-Mesenchymal Transition in Chronic Kidney Disease: Mechanisms and Therapeutic Targets.

📖 Top 30% JournalArticle

1 week ago • Bio-protocol

Measuring PINK1 Enzyme Activity in Individual Cells Using a Specialized ReporterMeasuring PINK1 Activity in Single Cells Using a PINK1 Kinase Activity Reporter.

📖 Top 50% JournalArticle

1 week ago • Immunogenetics

Genetic links between aging immune cells and immune system declineGenetic association of immunosenescence to immune decline.

📖 Top 30% JournalArticle

1 week ago • Journal of immunoassay & immunochemistry

Understanding the interaction between key cell growth and energy pathways and their role in metabolism and treatment of human diseasesDecoding the PI3K/Akt/mTOR-AMPK signalling nexus: molecular crosstalk, metabolic reprogramming and therapeutic targeting in human disease.

📖 Top 50% JournalArticle

1 week ago • Fitoterapia

Comparing five Indian spices for lifespan extension and anti-aging effects using chemical analysis and biological tests in yeastChronological lifespan extension evaluation-driven comparative study of five Indian dietary spices for geroprotective action via phytochemical profiling, bioactivity screening and network pharmacology in Saccharomyces cerevisiae.

📖 Top 50% JournalArticle

1 week ago • Bio-protocol

Separating Liver Cells with One or Two Nuclei Using Cell SortingIsolation of Mononucleated and Binucleated Hepatocytes by Flow Cytometry.

📖 Top 50% JournalArticle

1 week ago • Journal of inflammation research

SIRT1’s role in rheumatic diseases and its connection to traditional Chinese medicineSIRT1 as a Key Regulator in Rheumatic Diseases: Integrating Molecular Insights with Traditional Chinese Medicine Approaches.

📖 Top 20% JournalArticle

1 week ago • Journal of cell science

Vimentin filaments help form cell cleaning structures at contact points between energy and recycling systems during starvationVimentin intermediate filaments support autophagosome biogenesis at ER-endosome contact sites in response to starvation.

🎖️ Top 10% JournalArticle

1 week ago • Bioorganic & medicinal chemistry letters

Creation and early testing of resveratrol-like compounds that may affect cell aging proteins and reduce inflammationSynthesis and preliminary biological evaluation of resveratrol-like carbostyril derivatives as sirtuin 1 modulators and cyclooxygenase inhibitors.

📖 Top 50% Journal

1 week ago • Journal of biochemistry

New Connections Between Cell Recycling Centers and Supersulfides in Cell Energy and BalanceLysosomes and Supersulfides: Emerging Links in Cellular Metabolism and Homeostasis.

📖 Top 30% Journal

1 week ago • Cellular signalling

Poor mitochondrial cleanup and stress response affect cell aging after DNA damageImpaired mitochondrial quality control and stress signalling machinery modulate senescence induction by genotoxic challenge.

📖 Top 20% Journal

1 week ago • Brain research bulletin

Reducing DYNC1I1 lessens nerve cell loss and harmful protein buildup in Parkinson's disease modelsTargeting DYNC1I1 attenuates Parkinsonian neurodegeneration and α-synuclein accumulation in cellular and mouse models.

📖 Top 20% Journal

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Longevity & Aging Research Papers