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2 weeks ago • Journal of primary care & community health

Awareness, Confidence, and Use of Combined GLP-1 and GIP/GLP-1 Medicines Among Healthcare Providers and PharmacistsAssessing Awareness, Confidence and Utilization of Compounded GLP-1 and Dual GIP/GLP-1 Receptor Agonists Among Healthcare Clinicians and Pharmacists: A Comprehensive Survey Study.

📖 Top 20% JournalObservational Study

2 weeks ago • Nature communications

Heart and blood vessel outcomes of two diabetes drugs in kidney failure patients with heart failureCardiovascular outcome of glucagon-like peptide-1 receptor agonists vs dipeptidyl peptidase-4 inhibitor on end-stage kidney disease patients with heart failure: an emulated target trial in patients with diabetes.

🥈 Top 2% JournalRandomized Controlled Trial

1 month ago • Diabetes research and clinical practice

Effectiveness and safety of different once-weekly diabetes drugs that mimic gut hormonesEfficacy and safety of different once-weekly glucagon-like peptide-1 receptor agonists-A systematic review and Bayesian network meta-analysis.

🎖️ Top 10% JournalSystematic Review

3 weeks ago • Pharmaceuticals (Basel, Switzerland)

Comparing Oral and Under-the-Skin Semaglutide for Treating Obesity: Review of Effectiveness, Safety, and Patient ExperiencesOral vs. Subcutaneous Semaglutide for Obesity Treatment: A Systematic Review of Efficacy, Safety, and Patient-Oriented Outcomes.

📖 Top 20% JournalArticle

1 month ago • BMJ mental health

Cognitive symptoms in people with mental health diagnoses taking semaglutide: a study of 13,007 patients in the USACognitive signs and symptoms in people with a psychiatric diagnosis on semaglutide: a retrospective cohort study of 13 007 patients in the USA.

🥉 Top 5% JournalArticle

6 days ago • Clinical obesity

Differences in Weight Loss and Influencing Factors of GLP-1 Receptor Agonists and Dual Agonists in People with Obesity: A Meta-AnalysisWeight Reduction Heterogenicity and Mediators of GLP-1RAs and Dual Agonists for Individuals With Obesity: A Meta-Analysis.

📖 Top 30% JournalMeta-Analysis

2 weeks ago • Cancer control : journal of the Moffitt Cancer Center

Links Between Diabetes Drugs Called GLP-1 Receptor Agonists and Cancer Risk: A Review and AnalysisAssociations Between Glucagon-Like Peptide-1 Receptor Agonists (GLP-1RAs) and Cancer Risk: A Systematic Review and Meta-Analysis.

📖 Top 20% JournalSystematic Review

2 weeks ago • Diabetes therapy : research, treatment and education of diabetes and related disorders

Combined SGLT2 Inhibitors and GLP-1 Receptor Agonists and Their Link to Heart Attacks and Strokes in Type 2 DiabetesEffect of Combination Therapy with SGLT2 Inhibitors and GLP-1 Receptor Agonists on Myocardial Infarction and Stroke in Type 2 Diabetes: A Systematic Review and Meta-Analysis.

📖 Top 20% JournalSystematic Review

5 days ago • Diabetes/metabolism research and reviews

Low Levels of Active Thyroid Hormone Before Surgery, Especially in Women, Are Linked to Less Weight Loss and Diabetes Improvement After Bariatric Surgery in Adults with Normal Thyroid FunctionLow Preoperative Free Triiodothyronine, Particularly in Females, Is Associated With Reduced Weight Loss and Diabetes Remission After Bariatric Surgery in Euthyroid Adults.

🎖️ Top 10% JournalFulltext (Open License)Article

1 week ago • Frontiers in pharmacology

Oral small-molecule drugs that activate GLP-1 receptors: a new approach in heart and metabolism healthOral small-molecule GLP-1 receptor agonists: a new Frontier in cardiometabolic medicine.

📖 Top 20% JournalFulltext (Open License)Article

4 days ago • Medicine

Health outcomes linked to GLP-1 receptor agonist use in fatty liver disease with metabolism problems: A multinational studyClinical outcomes associated with GLP-1 receptor agonist use in metabolic dysfunction-associated steatohepatitis: A multinational cohort study.

📖 Top 50% JournalMulticenter Study

3 weeks ago • Frontiers in endocrinology

Tirzepatide’s effects on weight gain and blood sugar control after stomach surgery in people with type 2 diabetes and obesityClinical efficacy of tirzepatide for weight regain and suboptimal glycemic control following laparoscopic sleeve gastrectomy: a case series of three patients with obesity-associated type 2 diabetes.

🎖️ Top 10% JournalCase Reports

2 weeks ago • Pediatrics

Changes in Prescriptions of GLP-1 Medicines for Children Ages 8 to 11 with Obesity from 2019 to 2026Trends in GLP-1 Receptor Agonist Prescriptions for Children Ages 8 to 11 With Obesity: 2019-2026.

🥉 Top 5% JournalArticle

3 weeks ago • JAMA health forum

How Out-of-Pocket Costs Relate to Taking Semaglutide for Obesity in Adults with Private InsuranceOut-of-Pocket Costs and Adherence to Semaglutide for Obesity Among Commercially Insured Adults.

🥉 Top 5% JournalArticle

3 weeks ago • Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery

Comparing weight-loss surgeries and GLP-1 drugs for effectiveness: a review and analysisThe comparative effectiveness of bariatric operations versus GLP-1 RAs: a systematic review and meta-analysis.

📖 Top 20% JournalArticle

3 weeks ago • JAMA psychiatry

Glucagon-Like Peptide 1 Drugs, Death Rates, and Heart Health in Serious Mental IllnessGlucagon-Like Peptide 1 Receptor Agonists, Mortality, and Cardiovascular Outcomes in Serious Mental Illness.

🥇 Top 1% JournalArticle

3 weeks ago • Science advances

Designing long-lasting and brain-stable GLP-1 receptor drugs based on how IDE breaks down GLP-1IDE-mediated GLP-1 degradation as the basis for designing long-acting and CNS-stable GLP-1 receptor agonists.

🥈 Top 2% JournalArticle

4 weeks ago • The lancet. Diabetes & endocrinology

Mazdutide's safety and effectiveness in US adults with obesity or overweight: a phase 2 clinical trialEfficacy and safety of mazdutide in adults with obesity or overweight: a US-based, multicentre, phase 2, randomised, placebo-controlled clinical trial.

🥇 Top 1% JournalArticle

yesterday • Frontiers in endocrinology

Using Artificial Intelligence in Obesity Care: Current Evidence, Missing Links, and Key Steps for PracticeArtificial intelligence in obesity management: clinical evidence, translational gaps, and implementation priorities-a structured narrative review.

🎖️ Top 10% JournalArticle

yesterday • Diabetologia

Single molecule activating GLP-1 and APJ receptors improves metabolism, reduces abnormal blood fats, and normalizes liver fat and enzyme levels in high-fat diet miceUnimolecular GLP-1/APJ receptor co-agonism improves metabolism and dyslipidaemia as well as normalising hepatic triglyceride and aminotransferase elevation in high-fat-fed mice.

🥈 Top 2% JournalArticle

yesterday • PloS one

Different effects of semaglutide and CRV431 combined treatment on liver scarring and liver cancer in a fatty liver disease mouse modelDivergent effects of semaglutide and CRV431 Co-therapy on liver fibrosis and HCC in MASLD mouse model.

📖 Top 30% JournalArticle

2 days ago • Diabetologia

GPCRVP score reliably predicts how human GLP1R variants affect receptor functionThe GPCRVP score reliably predicts the impact of GLP1R human variants on receptor function.

🥈 Top 2% JournalArticle

3 days ago • Anaesthesia

Use of glucagon-like peptide-1 receptor drugs around surgery and patient outcomes in a national studyPeri-operative glucagon-like peptide-1 receptor agonist use and outcomes: a national prospective multicentre cohort study.

🥉 Top 5% JournalArticle

4 days ago • Journal of clinical medicine

How GLP-1 Medicines Affect Body Fat and Muscle in People with Overweight and ObesityThe Impact of Glucagon-like Peptide-1 (GLP-1) Receptor Agonists on Body Composition in Individuals with Overweight and Obesity: A Systematic Review and Meta-Analysis.

📖 Top 20% JournalArticle

4 days ago • International journal of molecular sciences

Combined GLP-1RA and Low-Dose IL-2 Reduce Immune Activation and Brain Inflammation Signals in Living OrganismsCombination GLP-1RA and Low-Dose IL-2 Modulates Peripheral Immune Activation and Attenuates CNS Inflammatory Transcript Signatures In Vivo.

📖 Top 20% JournalArticle

4 days ago • Frontiers in pharmacology

New advances and challenges in treating fatty liver disease linked to metabolism problemsA new era in the treatment of metabolic dysfunction-associated steatotic liver disease (MASLD): clinical breakthroughs and challenges.

📖 Top 20% JournalArticle

4 days ago • International journal of molecular sciences

Metabolic Fatty Liver Disease: From Molecular Causes to Treatment ApproachesFrom Molecular Mechanisms to Clinical Strategies: A Comprehensive Overview of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD).

📖 Top 20% JournalArticle

4 days ago • Nutrients

Using Lifestyle Changes with Incretin-Based Weight Loss Drugs: Combining Exercise, Diet, and Behavior for Lasting ResultsLifestyle Medicine as Co-Therapy During Incretin-Based Anti-Obesity Pharmacotherapy: Integrating Physical Activity, Nutrition, and Behavioral Strategies for Long-Term Success.

🎖️ Top 10% JournalArticle

4 days ago • Nutrients

Hidden Malnutrition in the GLP-1 Treatment Era: Micronutrient Levels, Protein Intake, and Muscle Mass as Important Nutritional FactorsHidden Malnutrition in the GLP-1 Era: Micronutrient Status, Protein Adequacy, and Lean Mass as Emerging Nutritional Considerations-A Narrative Review.

🎖️ Top 10% JournalArticle

4 days ago • Biology

Combined Exendin-4 and Rituximab Treatment Improves Insulin-Producing Cell Function and Slows Diabetes Progression in NOD MiceCombined Exendin-4 and Rituximab Treatment Improves β-Cell Function and Delays Disease Progression in NOD Mice.

📖 Top 20% JournalArticle

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GLP-1 Therapies Research Papers