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4 days ago • The Journal of clinical investigation

A specific brainstem circuit controls the unpleasant and appetite-reducing effects of GLP1R activatorsA single dorsal vagal complex circuit mediates the aversive and anorectic responses to GLP1R agonists.

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4 days ago • Cells

🎖️ Top 10% JournalArticle

4 days ago • Frontiers in medicine

Glucagon-like peptide-1 receptor drugs and tirzepatide linked to lower death, heart, and mental health risks in people with hidradenitis suppurativa and type 2 diabetes or obesityGlucagon-like peptide-1 receptor agonists and tirzepatide are associated with reduced mortality, cardiovascular, and psychiatric risks in patients with hidradenitis suppurativa and type 2 diabetes and/or obesity: a retrospective cohort study.

📖 Top 20% JournalArticle

5 days ago • Nature communications

Gene activity in human brain neurons that control energy balanceTranscriptome profiling of human hypothalamic agouti-related protein and proopiomelanocortin neurons regulating energy homeostasis.

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1 week ago • Frontiers in pharmacology

Reports of suicide and self-injury linked to liraglutide, semaglutide, and tirzepatide from European drug safety dataReporting patterns of suicide- and self-injury-related events involving liraglutide, semaglutide, and tirzepatide: data from the European pharmacovigilance database.

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1 week ago • Frontiers in endocrinology

GLP-1 drugs and the risk of kidney injury after heart procedures in people with Type 2 diabetesEffects of GLP-1 receptor agonists on the incidence of contrast-induced acute kidney injury in patients with Type 2 diabetes mellitus undergoing coronary interventions.

🎖️ Top 10% JournalArticle

1 week ago • F1000Research

Liraglutide's effects on weight and reproductive health in women with obesity and PCOSRole of Liraglutide in weight management and reproductive health in women with obesity and PCOS- A critical review of the evidence.

📖 Top 50% JournalArticle

1 week ago • Journal of eating disorders

Fasting gut hormone levels after long-term recovery from Anorexia NervosaFasting gut hormone levels following long-term recovery from Anorexia Nervosa: A cross-sectional study.

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1 week ago • Frontiers in endocrinology

Saudi doctors' knowledge, views, and use of diabetes medicines SGLT-2 inhibitors and GLP-1 receptor agonistsKnowledge, attitudes, and practices of Saudi physicians toward the use of SGLT-2 inhibitors and GLP-1 receptor agonists in patients with type 2 diabetes mellitus: a nationwide cross-sectional study.

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1 week ago • Current obesity reports

Changes in Fat Tissue After Incretin Treatments and Weight-Loss Surgery Beyond Just Losing WeightAdipose Tissue Remodeling Beyond Weight Loss: New Insights Into Incretin-Based Therapies and Bariatric Surgery.

🥉 Top 5% JournalArticle

1 week ago • Frontiers in endocrinology

Electroacupuncture may allow lower semaglutide doses in type 2 diabetes by increasing drug levels and reducing insulin cell deathElectroacupuncture enables semaglutide dose sparing in type 2 diabetes by boosting drug concentration and suppressing β-cell apoptosis.

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1 week ago • Frontiers in endocrinology

Tirzepatide and the risk of asthma attacks in people with type 2 diabetesTirzepatide and the risk of asthma exacerbations in patients with type 2 diabetes.

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1 week ago • Frontiers in endocrinology

Social and mental health challenges in children with fatty liver diseasePsychosocial aspects and mental health burden of pediatric MASLD.

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1 week ago • Frontiers in pharmacology

How Gut Bacteria, Medicines, and the Body Interact in Metabolic Syndrome and Type 2 DiabetesPharmacomicrobiomics in metabolic syndrome and type 2 diabetes: the microbiome-drug-host triad.

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2 weeks ago • Frontiers in endocrinology

Use of glucagon-like peptide-1 drugs before hospital does not lower opioid use but is linked to shorter hospital stays after joint replacement surgeryPrehospital glucagon-like peptide-1 receptor agonists are not associated with reduced inpatient opioid exposure but with shorter hospital length of stay after total joint arthroplasty.

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2 weeks ago • Frontiers in endocrinology

Unexplored Receptors in Diabetes: Their Role in Metabolism, Inflammation, and Drug DiscoveryOrphan GPCRs in diabetes mellitus: metabolic control, inflammation, and drug development.

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2 weeks ago • Endocrinology

IL-22 raises hormone-producing gut cells through STAT3 in human stem cell-based intestinal tissueIL-22 Increases Proglucagon-expressing Enteroendocrine Cells via STAT3 in Human iPSC-derived Intestinal Epithelium.

🎖️ Top 10% JournalArticle

2 weeks ago • Frontiers in pharmacology

How Tirzepatide may help treat obesity without diabetes: underlying actions, clinical results, and future possibilitiesTirzepatide for obesity without diabetes: mechanistic insights, clinical evidence, and future directions.

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2 weeks ago • Journal of internal medicine

New treatments for fatty liver disease and how they could be used in healthcareUpcoming therapies for steatotic liver disease: Translating breakthroughs into clinical practice.

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3 weeks ago • Frontiers in nutrition

Nutrition therapy in obesity-related heart failure treated with incretin drugsMedical nutrition therapy in incretin-treated obesity-related heart failure with preserved ejection fraction.

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3 weeks ago • Obesity surgery

Barriers to Getting Metabolic and Weight Loss Surgery in the United StatesWeighed Down by Paperwork: Identifying Barriers to Metabolic and Bariatric Surgery Evaluation in the United States.

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3 weeks ago • Journal of gastroenterology

Semaglutide effects in Japanese people with fatty liver disease linked to metabolism: a subgroup analysis of the ESSENCE trialSemaglutide in Japanese participants with metabolic dysfunction-associated steatohepatitis: a subgroup analysis of the ESSENCE trial.

🥉 Top 5% JournalArticle

3 weeks ago • ACS omega

Uneven Electric Charges Affect the Stability of GLP-1 Drug Clusters Under Different Salt, Chemical, pH, and Temperature ConditionsAnisotropic Electrostatics in the Instability of GLP‑1 Analog Micelles: Effects of Electrolytes, Denaturants, pH, and Temperature.

📖 Top 30% JournalArticle

3 weeks ago • Pharmaceuticals (Basel, Switzerland)

Combining Personalized Diets with GLP-1 Receptor Agonist Treatment: How It Works, Health Results, and Cost ConsiderationsIntegrating Precision Nutrition with GLP-1 Receptor Agonist Therapy: Mechanisms, Clinical Outcomes, and Pharmacoeconomic Implications.

📖 Top 20% JournalArticle

3 weeks ago • Nutrients

Why Fully Reporting Diet Matters in Studies of GLP-1 Receptor Agonist TreatmentsDietary Intake as an Undermeasured Potential Mediator: The Ethical Case for Complete and Transparent Dietary Reporting in GLP-1 Receptor Agonist Trials.

🎖️ Top 10% JournalArticle

3 weeks ago • Biomedicines

Different Protective Effects of Dulaglutide and Dexamethasone on Lung Scarring Caused by Methotrexate Linked to Energy and Cell Cleanup ProteinsDifferential Protective Actions of Dulaglutide and Dexamethasone in Methotrexate Induced Pulmonary Fibrosis: Relationship with AMPK and Beclin-1 Levels.

📖 Top 20% JournalArticle

3 weeks ago • Cancers

Use of GLP-1 Receptor Drugs in Cancer Survivors: Challenges and OpportunitiesGLP-1 Receptor Agonist Use in Cancer Survivors-Challenges and Opportunities: A Narrative Review.

🎖️ Top 10% JournalArticle

3 weeks ago • Biomedicines

Semaglutide’s effectiveness and safety in people with polycystic ovary syndromeEfficacy and Safety of Semaglutide in Patients with Polycystic Ovary Syndrome: A Scoping Review.

📖 Top 20% JournalArticle

3 weeks ago • Life (Basel, Switzerland)

Semaglutide may reduce brain damage caused by type 2 diabetes by lowering brain inflammation, stress, and cell deathSemaglutide Attenuates Type 2 Diabetes-Induced Neurotoxicity by Modulating Neuroinflammation, Oxidative Stress, and Neuroapoptosis.

📖 Top 30% JournalArticle

3 weeks ago • Pharmaceuticals (Basel, Switzerland)

Incretin-based treatments and their links to testosterone and hormone responses in men with low testosteroneEffects of Incretin-Based Therapies on Testosterone Levels and Incretin Response in Men with Hypogonadism: A Systematic Literature Review Following PRISMA 2020 Guidelines.

📖 Top 20% JournalArticle

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GLP-1 Therapies Research Papers