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1 month ago • Inflammation research : official journal of the European Histamine Research Society ... [et al.]

Agmatine may boost cell cleaning processes to reduce gut cell death caused by sepsisAgmatine induces mitophagy via the PTS-I2R pathway to increase autophagic flux and attenuate sepsis-induced intestinal epithelial cell apoptosis.

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1 month ago • Cancer chemotherapy and pharmacology

How antibiotics may also fight leukemia: ways they work and treatment possibilitiesOff-target anti-leukemic effects of antibiotics: mechanisms and therapeutic insights.

1 month ago • Phytotherapy research : PTR

Leaf Flavonoids from Lycium barbarum May Slow Aging by Regulating Cell Protection and Adhesion PathwaysLycium barbarum Leaf Flavonoids Exert Anti-Aging Effects by Regulating the Keap1-Nrf2-HO-1 and Cell Adhesion Molecule Signaling Pathways.

1 month ago • Journal of cardiology

Mitochondrial Cleanup in Heart and Blood Vessel Disease: Understanding How It Works and Possible TreatmentsMitophagy in Cardiovascular Disease: From Mechanistic Insights to Therapeutic Horizons.

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1 month ago • The EMBO journal

SenFlag gene pattern identifies aging cells in mouse and human tissues through shared gene activitySenFlag gene signature identifies senescent cells in mouse and human tissues through a conserved core transcriptional program.

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1 month ago • ACS applied materials & interfaces

Using Tiny Droplets to Move Healthy Mitochondria into Aging Stem Cells to Reduce Cell AgingDroplet Microfluidics-Enabled Mitochondrial Transfer from Young to Senescent MSCs to Ameliorate Cellular Senescence.

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1 month ago • Ageing research reviews

Using multiple biological measures and imaging to understand differences in organ aging for personalized elderly careFrom organ age gaps to precision geromedicine: Multi-omic and imaging frameworks for heterogeneous biological aging.

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1 month ago • The Journal of pharmacy and pharmacology

Traditional Chinese Medicine Treatments for Chronic Heart Failure: From Key Ingredients to Herbal RemediesTherapeutic strategies of traditional Chinese medicine for chronic heart failure: from active ingredients to herbal formulations.

1 month ago • Archives of biochemistry and biophysics

Reducing a Protein from Immune Cells May Ease Lung Scarring After Radiation by Slowing Cell Aging and InflammationTargeting CD8+ T Cell-Derived Granzyme K Alleviates Radiation-Induced Pulmonary Fibrosis by Attenuating Senescence and SASP.

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1 month ago • International immunopharmacology

Berbamine improves behavior in Huntington’s disease mice by blocking a cell signaling path and restoring damaged mitochondria cleanupBerbamine improves behavioral impairments in Huntington's disease mice models through inhibiting Src/AKT1/NFκB signaling pathway and attenuating Src-mediated mitophagy suppression.

1 month ago • Ageing research reviews

Aging of Bone Stem Cells: Causes, Effects on Bone Aging, and Possible TreatmentsAging of mesenchymal stem cells in bone aging: Mechanisms, impact, and therapeutic perspectives.

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1 month ago • Brain research bulletin

Research trends and biological roles of sirtuins in Alzheimer's diseaseGlobal Research Trends and Mechanistic Insights of Sirtuins in Alzheimer's Disease: A Bibliometric and Translational Review.

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1 month ago • Biogerontology

Emodin may reduce lung scarring after radiation by targeting cell aging through the mitochondrial DNA immune response pathwayEmodin alleviates radiation-induced pulmonary fibrosis by targeting cellular senescence via the mtDNA-cGAS-STING axis.

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1 month ago • Neurobiology of disease

CDKN1A helps protect movement-related neurons from Huntington's disease damageCDKN1A protects medium spiny neurons from Huntington's disease pathology.

1 month ago • Molecular biomedicine

Lack of Sirtuin 1 links long-term kidney disease inflammation to heart and blood vessel hardeningSirtuin 1 deficiency mediates chronic kidney disease-induced inflammaging cardiovascular calcification.

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1 month ago • Nature communications

A human-specific microRNA controls the timing of forming excitatory brain connectionsA human-specific microRNA controls the timing of excitatory synaptogenesis.

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1 month ago • Biochemical genetics

How Exercise May Influence Gene Control and RNA in Muscle Aging and LossThe Role of Exercise in Regulating Histone Modifications and Non-coding RNAs in Muscle Aging and Sarcopenia.

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1 month ago • Food research international (Ottawa, Ont.)

Butyrate from Lycium ruthenicum polysaccharide reduces chronic fatigue from sleep loss in mice by boosting brain immune cell cleanupWIPButyrate produced by the Lycium ruthenicum polysaccharide alleviated sleep deprivation-induced chronic fatigue syndrome in mice through promoting microglial autophagy.

🎖️ Top 10% Journal

1 month ago • Molecular neurobiology

Curcumin may reduce copper-related cell death by boosting cell cleanup through blocking a key growth signaling pathway in Parkinson's disease modelsCurcumin Attenuates Cuproptosis via Activating Autophagy Through Inhibition of the AKT/mTOR/P70S6K-Signaling Pathway in Parkinson's Disease Models.

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1 month ago • Molecular neurobiology

A Unified Cell-Death Process in the Nervous System Linked to Immune Activation and Long-Term Brain InflammationDissecting PANoptosis in the Nervous System: A Unified Cell-Death Mechanism Driving Neuroimmune Activation and Chronic Neuroinflammation.

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