OpenScience.ink

4 weeks ago • The EMBO journal

Local problems with cell cleanup cause widespread changes in nerve endings and increase brain resilienceLocal autophagy impairment triggers brain-wide presynaptic remodeling and resilience.

🥇 Top 1% Journal

4 weeks ago • Inflammopharmacology

Control of inflammatory signaling in Alzheimer's disease and the potential protective role of plant compoundsRegulation of NLRP3 inflammasome signaling in Alzheimer's disease: emerging neuroprotective role of phytochemicals.

📖 Top 20% Journal

4 weeks ago • Translational psychiatry

The genetic link between ADHD and shorter cell aging markers suggests brain development involvementThe genetic relationship between ADHD and shortened telomeres points to neurodevelopmental mechanisms.

🥉 Top 5% Journal

4 weeks ago • Molecular biology reports

How baicalein may help Parkinson's by reducing brain inflammation and cell death while boosting nerve growth and connectionsMechanistic insights into anti-parkinson effect of baicalein: from neuroinflammation and cell death to neurogenesis and synaptic plasticity.

📖 Top 30% Journal

4 weeks ago • American journal of physiology. Lung cellular and molecular physiology

DNA methylation linked to aging of lung repair cells in COPDDNA methylation as a driver of lung fibroblast senescence in COPD.

📖 Top 20% Journal

4 weeks ago • Molecular neurobiology

How Telomerase Location Inside Neurons Affects Control of Mitochondrial DNA Amount in Specific GenesSubcellular Localization of Telomerase Reverse Transcriptase Regulates Gene-Specific Modulation of Mitochondrial DNA Copy Number in Neuronal Cells.

🎖️ Top 10% Journal

4 weeks ago • Ageing research reviews

The Role of Cell Recycling, Aging, and Inflammation in Brain DegenerationThe Autophagy-Senescence-Inflammasome Axis: A Novel Triad in Neurodegenerative Diseases?

🥈 Top 2% Journal

4 weeks ago • Biochimica et biophysica acta. Reviews on cancer

How cell aging controls tumor growth in liver and bile duct cancers: key processes and pathwaysRegulation of tumorigenesis by cellular senescence: Mechanisms and pathways in liver cancer and cholangiocarcinoma.

4 weeks ago • Diabetes

Higher Levels of a Key Enzyme in Fat Tissue May Protect Obese Mice from Metabolic Problems Through Tiny Messenger ParticlesAdipose Tissue Overexpression of Nicotinamide Phosphoribosyltransferase Prevents Metabolic Dysfunction in Obese Mice via Extracellular Vesicles.

🥉 Top 5% Journal

4 weeks ago • BMC pulmonary medicine

Differences in genetic testing, screening, team care, and lung transplant treatment for inherited lung disease across locations and workplacesGeographical, institutional and workplace variability in genetic evaluation, screening practices, multidisciplinary care, and lung transplantation management for familial interstitial lung disease.

📖 Top 20% Journal

4 weeks ago • Chemico-biological interactions

Sulforaphane helps heart muscle cells survive low-oxygen stress by boosting energy system and cell recycling communicationSulforaphane protects cardiomyoblasts against chemical hypoxia by increasing mitochondrial-ER communication and autophagy.

📖 Top 20% Journal

4 weeks ago • Mechanisms of ageing and development

Elastin Fragments in the Blood May Promote Body-Wide Aging: Sources of These Aging-Related FragmentsCirculating elastin fragments drive systemic aging: Where do pro-aging elastin fragments come from? A mini-review.

4 weeks ago • Current biology : CB

Coumarins connect low iron levels to growth regulation in plantsCoumarins link iron deficiency to TOR inhibition in plants.

4 weeks ago • Clinical epigenetics

A DNA-based aging clock linked to death risk as a possible marker for frailtyExploring a targeted epigenetic clock based on mortality-associated CpGs as a potential biomarker for frailty.

🎖️ Top 10% Journal

4 weeks ago • The Journal of cell biology

Mitochondria moving between cells and being recycled when protein import failsIntercellular mitochondrial transfer and trans-mitophagy in response to protein import dysfunction.

4 weeks ago • Pediatric research

Using both cannabinoids and nicotine during pregnancy may increase aging in developing human lungsCo-exposure to cannabinoids and nicotine increases senescence in prenatal human lung development.

📖 Top 20% Journal

4 weeks ago • Odontology

How Changes in Gene Regulation Affect Gum Aging, Gum Disease, and Possible TreatmentsEpigenetic mechanisms of gingival aging: biological basis, periodontal implications, and therapeutic perspectives.

📖 Top 30% Journal

4 weeks ago • Free radical biology & medicine

Blocking VDAC1 grouping may reduce brain damage after blood flow returns by boosting removal of damaged mitochondria through less interaction with LONP1Inhibiting VDAC1 oligomerization attenuated cerebral ischemia-reperfusion injury by promoting mitophagy via reduced LONP1 interaction.

🥉 Top 5% Journal

4 weeks ago • Neuroscience bulletin

Faulty Energy Producers in Brain Immune Cells May Cause Memory Decline and Brain Cell Damage Through Immune SignalingDysfunctional Mitochondria in Microglia Drive Cognitive Aging and Neurodegeneration via cGAS-STING.

🎖️ Top 10% Journal

4 weeks ago • Life sciences

Targeting a specific cell death process controlled by PARP1 in Alzheimer's disease: how it works and possible treatmentsTargeting PARP1-dependent parthanatos in Alzheimer's disease: Mechanisms and therapeutic opportunities.

4 weeks ago • Scientific reports

Biological age predicts spread and survival in gastrointestinal cancer differently depending on patient ageAge-dependent prognostic value of biological age for metastasis and survival in gastrointestinal cancer.

📖 Top 20% Journal

4 weeks ago • Molecular brain

Zinc-driven lysosome activation by 1H10 boosts cell cleanup and reduces tau build-up in Alzheimer's modelsZinc-mediated lysosomal activation by 1H10 enhances autophagy and attenuates tau pathology in Alzheimer's disease models.

📖 Top 20% Journal

4 weeks ago • Metabolic brain disease

Transthyretin's protective role in Parkinson's disease and brain degenerationTransthyretin at the crossroads of neurodegeneration: a silent guardian in Parkinson's disease.

📖 Top 20% Journal

4 weeks ago • The Journal of steroid biochemistry and molecular biology

β-sitosterol and new neuroprotection approaches targeting multiple systems and the gut-brain connection in neurodegenerative diseasesβ-sitosterol and next-generation neuroprotection for multi-target strategies and the gut-brain axis in neurodegenerative diseases.

📖 Top 30% Journal

4 weeks ago • Acta pharmacologica Sinica

Targeted protein breakdown connecting chemical biology and medical applicationsTargeted protein degradation: bridging chemical biology and clinical translation.

🥉 Top 5% Journal

4 weeks ago • Autophagy

Restoring cell recycling to slow eye tissue breakdown by targeting the SNAI1-LAMP3 pathwayTargeting the SNAI1-LAMP3 axis to restore lysosomal function and alleviate autophagic flux impairment to delay retinal degeneration.

🥈 Top 2% Journal

4 weeks ago • Inflammation

Cellular Cleanup of Damaged Mitochondria in Fatty Liver Disease Linked to Metabolism: How It Works, Controls, and Treatment PossibilitiesMitophagy in Metabolic Dysfunction-Associated Fatty Liver Disease: Mechanisms, Regulatory Networks, and Therapeutic Perspectives.

📖 Top 20% Journal

4 weeks ago • American journal of physiology. Endocrinology and metabolism

Multiple biological changes linked to exercise in post-menopausal womenBridging the gap: Multi-omic Insights into Exercise Responses in Post-Menopausal Women.

🎖️ Top 10% Journal

1 month ago • PLoS pathogens

Staphylococcus aureus changes arginine use to promote mammary gland aging through immune and tissue cell interactionStaphylococcus aureus rewires arginine metabolism to drive mammary aging via macrophage-epithelial crosstalk.

🥉 Top 5% Journal

1 month ago • Current pharmaceutical design

Resveratrol's potential to reduce inflammation by affecting the NLRP3 immune responseResveratrol and the NLRP3 Inflammasome: Unlocking the Anti-inflammatory Potential of a Natural Compound.

📖 Top 50% Journal

← prevpage 17 of 18next →

Latest Longevity & Aging Research Papers