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3 weeks ago • Kidney medicine

Immune responses after two-strain COVID-19 mRNA vaccines in patients on kidney dialysisHumoral and Cellular Immune Responses Following Bivalent SARS-CoV-2 mRNA Vaccines in Patients Undergoing Hemodialysis: A Prospective Cohort Study.

📖 Top 20% JournalArticle

3 weeks ago • Cell reports

Genetic differences in immune system and blood cell genes influence antibody protection from COVID-19 mRNA vaccinesGenetic variation in HLA, IGKV, and HHEX loci influences mRNA vaccine-induced humoral protection against COVID-19.

🥈 Top 2% JournalArticle

3 weeks ago • Seminars in cancer biology

RNA changes and metabolism in cancer: how they interact and what this means for treatmentRNA modifications and metabolism in cancer: mechanisms, cross-talk and therapeutic implications.

🥈 Top 2% JournalArticle

3 weeks ago • ACS applied materials & interfaces

A Brain-Targeted Nanoparticle System to Reduce Brain Inflammation After Stroke Using Combined Antioxidant and Anti-Inflammatory ActionsA Brain-Targeted Nanozyme System for Alleviating Poststroke Neuroinflammation via Synergistic Antioxidant and Anti-inflammatory Mechanisms.

🎖️ Top 10% JournalArticle

3 weeks ago • Biomaterials advances

Using lab-made nanoparticle carriers to restore function in aged donor liversThe application of engineered exosome-mimetic lipid nanoparticles in the hepatic rejuvenation of aged donor livers.

📖 Top 20% JournalArticle

3 weeks ago • Nature biotechnology

Faster finding of heat-resistant mRNA vaccine nanoparticles using efficient AIAccelerated discovery of thermostable mRNA-lipid nanoparticle vaccines using data-efficient AI.

🏆 Top 0.1% JournalArticle

3 weeks ago • Trends in biotechnology

Improving mRNA treatments from creation to deliveryAdvancing mRNA therapeutics from design to delivery.

🥉 Top 5% JournalArticle

3 weeks ago • International journal of pharmaceutics

Dual-drug linked ionizable lipids for delivering genetic material and targeted treatment of brain tumorsDual-drug conjugated ionizable lipids for nucleic acid delivery and multidimensional targeted therapy of brain tumors.

📖 Top 20% JournalArticle

3 weeks ago • International journal of pharmaceutics

Physical, chemical, and biological testing of a pharmaceutical-grade lipid for reliable large-scale production of RNA-loaded lipid nanoparticlesPhysicochemical and biological evaluation of a GMP‑grade ionizable lipid for robust and scalable manufacturing of siRNA- and mRNA-loaded lipid nanoparticles.

📖 Top 20% JournalArticle

4 weeks ago • ACS physical chemistry Au

How pH Changes Affect T7 RNA Polymerase Activity Revealed by Molecular SimulationsMolecular Basis of pH-Dependent Activity in T7 RNA Polymerase Revealed by Constant pH Replica Exchange Molecular Dynamics.

📖 Top 20% JournalArticle

4 weeks ago • Journal of drug targeting

How Individual Building Blocks Help Cell-Penetrating Peptides Cross Cell BarriersOvercoming Cellular Barriers with Cell-Penetrating Peptides: Functional Roles of Individual Amino Acids.

📖 Top 20% JournalArticle

1 month ago • Molecular therapy. Nucleic acids

How codon choices in modified mRNA lower immune reactions but keep vaccine effectivenessCodon-dependent translation of N1-ethylpseudouridine-modified mRNA reduces innate immunity while preserving vaccine immunogenicity.

🥉 Top 5% JournalArticle

1 month ago • Pharmaceutical research

Computer-Designed mRNA Vaccine Targeting Three Types of Equine Encephalitis VirusesComputational Design of a Trivalent Multi-Epitope mRNA Vaccine Candidate Against Western, Eastern, and Venezuelan Equine Encephalitis Viruses.

📖 Top 20% JournalArticle

1 month ago • Current opinion in chemical biology

Peptide-based delivery of CRISPR from lab tests to bloodstreamPeptide-mediated CRISPR delivery: From dish to bloodstream.

🥉 Top 5% JournalArticle

4 days ago • BioImpacts : BI

RNA Vaccines: Understanding Their Design, How They Are Delivered, and How They Are UsedRNA vaccines in motion: A multidisciplinary exploration of design, delivery, and deployment.

📖 Top 50% JournalArticle

6 days ago • Bioanalysis

Challenges and possible solutions in analyzing new small-molecule drugs: a European industry perspectiveEuropean Bioanalysis Forum cross-industry perspective on emerging small-molecule modalities: bioanalytical challenges and potential mitigation strategies.

📖 Top 50% JournalArticle

1 week ago • Molecular biology reports

Why Delivering siRNA to Treat Brain Diseases Often Fails: Body Barriers, Nanoparticle Design, and Future ApproachesWhy does siRNA delivery still fail in neurodegenerative diseases? Biological barriers, nanocarrier engineering, and future translational directions.

📖 Top 30% JournalArticle

1 week ago • Therapeutic delivery

How the design of tiny fat-based carriers affects their drug releaseMechanistic insights into nanostructured lipid carriers: from lipid architecture to drug release behavior.

📖 Top 50% JournalArticle

1 week ago • Critical reviews in therapeutic drug carrier systems

Targeted Drug Delivery to Tumors: From Traditional to New TechnologiesTumor Specific Drug Delivery: Conventional to Advanced Technologies.

📖 Top 50% JournalArticle

1 week ago • Current gene therapy

Smart Tiny Carriers That Deliver siRNA and Respond to Signals for Targeted Gene SilencingSMART Nanocarriers for siRNA Delivery: Stimuli-Responsive Platforms for Targeted Gene Silencing.

📖 Top 30% JournalArticle

1 week ago • Human vaccines & immunotherapeutics

Development of mRNA Vaccines for ShinglesDevelopment of mRNA vaccines against herpes zoster.

📖 Top 20% JournalArticle

1 week ago • Current gene therapy

MicroRNA Treatments in Cancer: Reviewing Their Potential and Challenges for Medical UseMicroRNA Therapeutics in Cancer: Revisiting the Promise and Understanding the Limitations of Clinical Translation.

📖 Top 30% JournalArticle

1 week ago • Journal of liposome research

Key factors affecting accurate ultrasound creation of fat-based nanoparticlesCritical factors influencing the precise ultrasound-mediated production of lipid nanoparticles.

📖 Top 50% JournalArticle

2 weeks ago • Nanomedicine (London, England)

mRNA nanomedicine for healing diabetic wounds: progress in delivery, immune response, and tissue repairmRNA-based nanomedicine for diabetic wound repair: advances in LNP delivery, immune modulation, and regenerative pathways.

📖 Top 50% JournalArticle

2 weeks ago • Current drug targets

Graphene-based delivery systems carrying self-boosting RNA, circular RNA, and immune activators for cancer immunotherapyStimuli-responsive Graphene Nanoplatforms Co-delivering Self-amplifying RNA, circRNA, and cGAMP for Cancer Immunotherapy: A Narrative Review.

📖 Top 30% JournalArticle

3 weeks ago • Human vaccines & immunotherapeutics

Designed tiny particle vaccines for preventing and treating cancer and infectionsEngineered nanovaccines for prophylactic and therapeutic immunotherapy against cancer and infectious disease.

📖 Top 20% JournalArticle

3 weeks ago • Technology in cancer research & treatment

Ultrasound-Activated Bionic Nanoparticles for Combined Therapy Against Medullary Thyroid CancerIn Vitro Investigation of LIFU-Triggered, Visualizable Bionic Nanoparticles for a "Three-In-One" Therapy Against Medullary Thyroid Carcinoma.

📖 Top 30% JournalArticle

4 weeks ago • Current pharmaceutical design

New Developments in Using Emulsomes Nanoparticles for Cancer TreatmentEmulsomes in Cancer Therapy: Emerging Advances in Nanomedicine.

📖 Top 50% JournalArticle

4 weeks ago • Current drug delivery

Challenges and Future Approaches for Delivering microRNA Treatments from Lab to ClinicFrom Laboratory to Clinic: Translational Challenges, Lessons, and Future Strategies for microRNA Delivery Systems.

📖 Top 50% JournalArticle

4 weeks ago • Current pharmaceutical design

mRNA Medicines: Progress, Challenges, and Future Possibilities in HealthcareMessenger RNA (mRNA) Therapeutics: Advances, Challenges, and Future Perspectives in Modern Medicine.

📖 Top 50% JournalArticle

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