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1 week ago • ACS pharmacology & translational science

New RNA Treatments Targeting Inflammation in the Front Part of the Eye: How They Work and Their Medical PromiseEmerging RNA-Based Therapeutic Strategies for Inflammatory Ophthalmic Disorders of the Anterior Segment: Mechanistic Insights and Translational Potential.

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1 week ago • ACS chemical biology

Functions of Non-Double-Layer Lipids in Biology, Disease, and Drug DeliveryLipid Chemistry beyond the Bilayer: Roles for Nonbilayer Lipids in Biology, Disease, and Delivery.

🎖️ Top 10% JournalArticle

1 week ago • Biomaterials

Specially designed lipids control RNA assembly in mineral-rich environmentsChemically tailored lipids mediate solid-phase RNA programming of mineralized microenvironments.

🥉 Top 5% JournalArticle

1 week ago • Biomaterials advances

pH-sensitive polymer that changes from water-attracting to water-repelling to help cells take in mRNA using lightPolymer-photosensitizer conjugate exerting pH-responsive hydrophilic-to-hydrophobic conversion for cell-specific photochemical internalization of mRNA.

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1 week ago • Science China. Life sciences

Improving fat-based particles to lower liver buildup and boost mRNA delivery at target sitesOptimization of lipid nanoparticles reduces hepatic accumulation and enhances local delivery of mRNA.

🥉 Top 5% JournalArticle

1 week ago • European journal of pharmacology

Survivin mRNA lipid nanoparticles activate killer T cells and memory response for effective oral cancer immunotherapySurvivin mRNA-lipid nanoparticles promote activation of CD8+Granzyme B+ T cells and effector memory formation for effective oral cancer immunotherapy.

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1 week ago • International journal of pharmaceutics: X

Distribution of mRNA-carrying lipid nanoparticles in the inner ear of newborn miceExploration of biodistribution of mRNA-delivering lipid nanoparticles in the neonatal mouse inner ear.

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1 week ago • Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology

Lipid-Based Nanomedicines for Inflammatory Diseases: Current Advances and Future OutlookLipid-Based Nanotherapeutics for Inflammatory Disorders: Current Progress and Future Perspectives.

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2 weeks ago • Current opinion in chemical biology

Fluorescent tagging methods for genetic material and their use in studying RNA deliveryFluorescence labelling strategies for nucleic acids and current applications in studying RNA delivery.

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2 weeks ago • Vaccine

Circular RNA Vaccines for Pvs25 Trigger Antibodies That May Block Malaria TransmissionCircular RNA vaccines encoding Pvs25 induce antibodies that block Plasmodium vivax transmission.

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2 weeks ago • Vaccine

SARS-CoV-2 mRNA vaccine immune response over time in inflammatory bowel disease patients, linked to anti-TNF treatment and ageLongitudinal SARS-CoV-2 mRNA vaccine immunogenicity in inflammatory bowel disease in relation to anti-TNF therapy and age: a prospective cohort study.

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2 weeks ago • Lab on a chip

Designing microfluidic channels for mRNA lipid nanoparticles: review of mixing methods, particle structures, and biological resultsMicrofluidic channel engineering for mRNA-LNPs: a systematic review of mixing strategies, nanostructures, and biological performance.

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2 weeks ago • Signal transduction and targeted therapy

Bioengineering methods to boost the immune response of mRNA vaccinesBioengineering strategies for improving the immunogenicity of mRNA vaccines.

🥇 Top 1% JournalArticle

2 weeks ago • Angewandte Chemie (International ed. in English)

Lipid Nanoparticles Using Molecular Recognition Boost Cancer Immunotherapy by Changing the Tumor EnvironmentSupramolecular Pretargeting Lipid Nanoparticles Based on Host-Guest Recognition Potentiate Cancer Immunotherapy by Reprogramming Tumor Microenvironment.

🥇 Top 1% JournalArticle

2 weeks ago • Journal for immunotherapy of cancer

IL7R mRNA treatment boosts cancer-fighting T cells and slows tumor growth in animal modelsIL7R mRNA therapy enhances antitumor T cell immunity and suppresses tumor growth in preclinical tumor models.

🥈 Top 2% JournalArticle

2 weeks ago • International journal of nanomedicine

Using DNA Barcodes to Find Lipid Nanoparticles That Deliver TRAIL-mRNA to Lungs to Kill Tumor Cells in a Metastasis ModelHigh-Throughput DNA Barcoding Identifies Lipid Nanoparticles for Lung Delivery of TRAIL-mRNA to Induce Tumor Cell Death in Experimental Metastasis Model.

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2 weeks ago • ACS applied bio materials

Fluorescent lipid nanoparticles designed to target two sites for improved small activating RNA deliveryReactive Polymer-Engineered Dual-Targeting Fluorescent Lipid Nanoparticles for Enhanced saRNA Delivery.

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2 weeks ago • International journal of nanomedicine

Challenges in Nanoparticle Delivery for Immune Cell Engineering: From Cell Uptake to Escaping Internal CompartmentsThe Nanoparticle Delivery Gap in Immune Cell Engineering: From Uptake to Endosomal Escape.

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2 weeks ago • ACS applied bio materials

C-5 Induction Boosts Uracil-Based Lipid Nanoparticles to Improve Redox-Driven Treatment in Liver CancerCorrelating the C-5 Induction Effect on Uracil-Based Nucleoside Lipid Nanoparticles for Enhanced Redox-Mediated Therapeutic Efficacy in Hepatocellular Carcinoma.

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2 weeks ago • Small (Weinheim an der Bergstrasse, Germany)

Fast and Efficient Capture of Engineered Cell Particles Carrying Functional Proteins Using Internal Twin-Strep TagsRapid and Efficient Affinity Isolation of Engineered Extracellular Vesicles Encapsulating Functional Proteins via Internal Twin-Strep Tetraspanin Tagging.

🥈 Top 2% JournalArticle

3 weeks ago • International journal of pharmaceutics

Designing smart lipid nanoparticles for breast cancer using AI and personalized medicine to improve safety and effectivenessEngineering smart polymeric lipid nanoparticles for breast cancer: The convergence of AI and medical personalization to enhance efficacy and safety.

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3 weeks ago • Nanomedicine : nanotechnology, biology, and medicine

Liver delivery of FXR mRNA using lipid nanoparticles improves low-dose FXR drug treatment for MASLDHepatic delivery of FXR mRNA via lipid nanoparticles enhances the efficacy of a low-dose FXR agonist in the treatment of MASLD.

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3 weeks ago • Biomaterials

Designing tiny cell particles to deliver multiple treatments for silicosis and similar scarring lung diseasesEngineering extracellular vesicles for multi-cargo co-delivery in silicosis and related fibrotic diseases: design strategies and translational prospects.

🥉 Top 5% JournalArticle

3 weeks ago • Vaccine

A clade 2.3.4.4b HA mRNA vaccine may protect mice against different types of human H5N1 flu virusesCross-clade protection against human H5N1 isolates by a clade 2.3.4.4b HA mRNA vaccine in mice.

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3 weeks ago • Antibody therapeutics

Llama mRNA-LNP vaccination allows quick isolation of specific nanobodies using cell-based selectionLlama mRNA-LNP immunization enables rapid isolation of target specific nanobodies using cell-based panning.

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3 weeks ago • Cell stem cell

Targeted gene editing of blood-forming stem cells inside the bodyEditing cells in place: Targeted in vivo gene editing of hematopoietic stem cells.

🥇 Top 1% JournalArticle

3 weeks ago • Journal of materials chemistry. B

How the changing biological identity and movement of targeted nanomedicines affect precise delivery in the bodyFate-informed chemistry of targeted nanomedicines: dynamic biological identity, barrier redistribution, and precision delivery.

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3 weeks ago • Vaccine

Summary of the 2025 Workshop on Vaccine Safety After COVID-19Summary of 2025 Society of Toxicology Workshop "Vaccine Toxicology in the Post-COVID Era".

📖 Top 20% JournalConference Proceedings

3 weeks ago • International journal of pharmaceutics

Using artificial intelligence to design eco-friendly, biodegradable, and responsive tiny drug carriers for precise treatmentArtificial intelligence-guided green and circular nanotechnology: designing sustainable, biodegradable, and bioresponsive nanocarriers for next-generation precision drug delivery.

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3 weeks ago • International journal of pharmaceutics

New nanomedicine methods that wake dormant cells to help tissue repairEmerging nanomedicine upshot: Reprogramming cellular dormancy for tissue regeneration.

📖 Top 20% JournalArticle

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