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4 weeks ago • Vaccines

Development and Future Uses of Circular RNA Vaccines for Viral DiseasesResearch Progress, Application, and Industrialization Prospects of Circular RNA Vaccines in Viral Diseases.

📖 Top 20% JournalArticle

4 weeks ago • Molecules (Basel, Switzerland)

Small Activating RNAs: A Organized Database and Guide to Designing ThemSmall Activating RNAs: A Curated Database and an Overview of Rational Design Principles.

📖 Top 20% JournalArticle

4 weeks ago • Vaccines

Immune-Boosting Effects of Human IFN-β mRNA in Primary Human Myeloid Cells Depend on TimingTiming-Dependent Immunostimulatory Activity of Human IFN-β mRNA in Primary Human Myeloid Cells.

📖 Top 20% JournalArticle

4 weeks ago • Frontiers in genome editing

Using CRISPR-Cas9 Gene Editing for Treating Cancer and Inherited Genetic DiseasesClinical translation of CRISPR-Cas9 therapeutics in cancer and inherited genetic disorders.

🎖️ Top 10% JournalArticle

1 month ago • Medical sciences (Basel, Switzerland)

COVID-19 mRNA Vaccines as Immune Modifiers Beyond Targeting Specific AntigensCOVID-19 mRNA Vaccines as Antigen-Agnostic Immunomodulators: A Repurposing Perspective.

🎖️ Top 10% JournalArticle

1 month ago • Cells

mRNA Vaccines as New Immune Treatments for Digestive System CancersmRNA Vaccines as Novel Immunotherapeutic Approaches in Gastrointestinal Cancers.

🎖️ Top 10% JournalArticle

1 week ago • Journal of toxicology

Safety Concerns and Risks of Modified mRNA Vaccine Technology Based on COVID-19 ExperienceToxicological Vulnerabilities and Emerging Safety Signals in Modified mRNA Vaccine Technology: A Narrative Review of the COVID-19 Experience.

📖 Top 30% JournalArticle

2 weeks ago • FEBS open bio

Using Fluorine to Adjust How Molecules and Tiny Systems Interact with Living ThingsFluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter.

📖 Top 20% JournalArticle

4 weeks ago • Micromachines

Combining Artificial Intelligence and Microfluidics for Drug DeliveryIntegration of Artificial Intelligence and Microfluidics for Drug Delivery Applications.

📖 Top 50% JournalArticle

1 month ago • Tropical medicine and infectious disease

Improving Mpox Vaccines with Targeted Antigen Design, New Delivery Methods, and Immune Protection MarkersToward Precision Vaccinology for Mpox: Rational Antigen Design, Next-Generation Platforms, and Immune Correlates of Protection.

📖 Top 30% JournalArticle

1 week ago • Journal of the Egyptian National Cancer Institute

Cancer nanomedicine and RNA/lipid nanoparticle systems in cancer treatment: development progress, challenges in use, and chances for precise therapiesCancer nanomedicine and RNA/Lipid nanoparticle platforms in oncology: developmental evolution, translational barriers, and precision-therapy opportunities.

📖 Top 50% JournalArticle

2 days ago • Molecular pharmaceutics

Using Stronger Fat-Based Nanoparticles to Lower PD-L1 Levels in Breast Cancer CellsReinforcement of Solid Lipid Nanoparticles for Targeted PD-L1 Downregulation in Breast Cancer.

📖 Top 20% JournalArticle

2 days ago • Kidney research and clinical practice

Clinical outcomes of third mRNA COVID-19 vaccine doses in patients on hemodialysis across the countryClinical effects of third doses of mRNA COVID-19 vaccines among hemodialysis patients: a nationwide retrospective cohort study.

📖 Top 20% JournalArticle

2 days ago • Journal of pharmaceutical sciences

Measuring how many particles are in mRNA lipid nanoparticles, what affects their production, and why it matters for product qualityParticle occupancy in mRNA lipid nanoparticles: Measurement, manufacturing determinants, and relevance to product quality.

📖 Top 30% JournalArticle

2 days ago • Mucosal immunology

Different control of flu vaccine B cell responses targeting the virus head versus stem in vaccinated and unvaccinated infant African green monkeysDistinct regulation of influenza HA head- versus stem-specific B cell responses in HA mRNA-LNP vaccinated and naïve infant African green monkeys.

🥉 Top 5% JournalArticle

4 days ago • Cancer discovery

Cancer Vaccines Targeting Common Tumor Markers Often Fail to WorkShared-Antigen Cancer Vaccines Keep Falling Short.

🥇 Top 1% JournalArticle

5 days ago • Molecular therapy. Nucleic acids

Detailed lab testing and body processing of RNA-made PGT121-LS antibody against HIVRNA-encoded PGT121-LS anti-HIV antibody: Comprehensive preclinical characterization and translational pharmacokinetics.

🥉 Top 5% JournalArticle

5 days ago • Advanced materials (Deerfield Beach, Fla.)

New Lipid Nanoparticle Methods for Delivering RNA Treatments Outside the LiverEmerging Lipid Nanoparticle Targeting Strategies for Extrahepatic Delivery of RNA Therapeutics.

🥇 Top 1% JournalArticle

5 days ago • Bioactive materials

Injectable mRNA-made short fibers send timed mechanical and genetic signals to reshape support cell structure for nerve healingInjectable mRNA-engineered short fibers deliver temporally coupled mechano-genetic signals to reprogram Schwann cell cytoskeleton for nerve repair.

🥈 Top 2% JournalArticle

6 days ago • International journal of pharmaceutics

Lipid-polymer nanoparticles stable for inhalation to deliver mRNA in advanced lab models of the lungsNebulization-stable lipid-polymer hybrid nanoparticles for mRNA delivery in advanced in vitro respiratory models.

📖 Top 20% JournalArticle

6 days ago • International journal of pharmaceutics

Measuring protein production from mRNA-LNPs: how dose and previous exposure affect resultsIVIS assessment of mRNA-LNP protein expression: effects of dosing parameters and prior LNP exposure.

📖 Top 20% JournalArticle

6 days ago • International journal of nanomedicine

Using Peptides to Deliver Active Substances Exactly Inside CellsPeptide-Mediated Precise Intracellular Delivery of Bioactive Substances.

🎖️ Top 10% JournalArticle

6 days ago • ACS applied materials & interfaces

Improving Cell Delivery for Aptamer-Driven Ubiquitin-Based Breakdown of c-Met ProteinOptimizing Endosomal Escape for Effective Aptamer-Based Ubiquitin-Mediated Degradation of c-Met.

🎖️ Top 10% JournalArticle

1 week ago • International journal of nanomedicine

Using Lipid Nanoparticles to Treat Brain Fungal Infections and Support the Immune ResponseLipid Nanoparticle-Mediated Antifungal and Immunomodulatory Therapy for Neuromycoses.

🎖️ Top 10% JournalArticle

1 week ago • China CDC weekly

Two mRNA Approaches for Dog Rabies Vaccines: Progress, Challenges, and Potential Use in the FieldTwo mRNA Platforms for Canine Rabies Vaccines: Advances, Limitations, and Field Application Prospects.

📖 Top 20% JournalArticle

1 week ago • Trends in pharmacological sciences

Designing monocytes and macrophages to improve medical treatmentsEngineering monocytes and macrophages for therapeutic control.

🥈 Top 2% JournalArticle

1 week ago • Clinical pharmacology and therapeutics

Modeling how unconjugated antisense oligonucleotides and GalNAc-linked small interfering RNAs spread in blood and tissues of animals and humansToward a Platform PBPK Model to Characterize the Plasma and Tissue Disposition of Unconjugated Antisense Oligonucleotides and GalNAc-Conjugated Small Interfering RNAs in Preclinical Species and Human.

🥉 Top 5% JournalArticle

1 week ago • Analytica chimica acta

Methods for Measuring How Efficiently mRNA Gets Its Protective CapAnalytical methods for estimation of the mRNA capping efficiency - A comprehensive review.

📖 Top 20% JournalArticle

1 week ago • International journal of biological macromolecules

Zein-based hybrid nanoparticles for delivering genes without viruses: A reviewZein-based hybrid nanocarriers for non-viral gene delivery: A review.

📖 Top 20% JournalArticle

1 week ago • Advanced materials (Deerfield Beach, Fla.)

Local mRNA Treatments Delivered to Accessible Body Areas for Targeting DiseasesAnatomically Accessible Local mRNA Therapeutics: From Anatomical Access to Disease-Focused Applications.

🥇 Top 1% JournalArticle

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