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3 weeks ago • Biotechnology journal

Advances and Future Directions of Tiny Particle Delivery Systems for mRNA Vaccines Controlled by MetabolismProgress and Prospects of Nanodelivery Systems in Metabolism-Regulated mRNA Vaccines.

📖 Top 30% Journal

1 month ago • Human vaccines & immunotherapeutics

New vaccine boosters combining nanotechnology, immune system understanding, and computer methods for precise vaccinesNext-generation vaccine adjuvants: Integrating nanotechnology, systems immunology, and computational approaches for precision vaccinology.

📖 Top 20% Journal

1 week ago • Journal of applied genetics

A new mRNA vaccine targeting multiple parts of E. coli designed using computer methodsA novel multi-epitope mRNA vaccine against Escherichia coli using an in silico reverse vaccinology approach.

📖 Top 50% JournalArticle

3 weeks ago • Mass spectrometry (Tokyo, Japan)

Using the Peptide Barcode Method to Quickly Screen mRNA Control SequencesUse of the Peptide Barcode Method for Efficient Screening of mRNA Expression Control Sequence.

3 weeks ago • Central nervous system agents in medicinal chemistry

Lipid Nanoparticles That Respond to Stimuli for Targeted Brain Disease Treatment: Current Challenges and Future ProspectsStimuli-responsive Lipid-based Nanoplatforms for Targeted Therapy of Brain Diseases: Current Challenges and Future Directions.

📖 Top 50% Journal

4 days ago • bioRxiv : the preprint server for biology

Loading RNA into fat-based nanoparticle carriersPost-loading ribonucleic acid into lipid nanoparticle carriers.

Preprint

1 week ago • Research square

Improving HPV16 E6/E7 mRNA Vaccine by Adding HSV-1 gD Epitope and Immune-Boosting Agents in StepsStepwise Enhancement of HPV16 E6/E7 mRNA Vaccine Efficacy Using HSV-1 gD Epitope Incorporation and Immune-Modulating Agents.

Preprint

1 week ago • Molecular therapy. Advances

Restoring eye cell function in choroideremia by delivering mRNA to the retinamRNA delivery to the retina restores REP1 function in choroideremia.

2 weeks ago • Journal of controlled release : official journal of the Controlled Release Society

The often overlooked later steps in making lipid nanoparticlesThe hidden half of lipid nanoparticle manufacturing: Downstream processing.

2 weeks ago • Proceedings of the National Academy of Sciences of the United States of America

Fast production of personalized cancer vaccines using lab-made RNA that makes proteins without cell-based methodsIVT-free, chemically synthesized protein-encoding RNA oligonucleotides for rapid production of personalized cancer vaccines.

3 weeks ago • Cell biomaterials

mRNA-based MRI agent for accurate diagnosis of brain tumors and treatment-related changesmRNA-based MRI contrast agent for precise diagnosis of glioma and pseudoprogression.

1 week ago • Journal of virology

Testing a vaccine targeting multiple proteins of EEHV1A in Asian elephantsEvaluation of a multiantigen mRNA vaccine against EEHV1A in Asian elephants.

Article

1 week ago • Journal of virology

First signs that an mRNA vaccine can protect young elephants naturally infected with EEHV1AFirst evidence of clinical protection from an EEHV1A mRNA vaccine in naturally infected juvenile elephants.

Article

1 week ago • Journal of medical virology

COVID-19 mRNA Vaccines Trigger Neutralizing Antibodies and Change Immune Responses in People with HIVSARS-CoV-2 mRNA Vaccination Induces Neutralizing Antibodies and Type I IFN Changes in People Living With HIV.

Article

3 weeks ago • bioRxiv : the preprint server for biology

Special Thyclotides Help Deliver Active Peptides Efficiently into CellsCell Penetrating Thyclotides Facilitate Efficient Delivery of Bioactive Peptides into Cells.

1 week ago • bioRxiv : the preprint server for biology

mRNA Nanoparticles Producing a Key Bacterial Protein Trigger Wide-Ranging Systemic and Mucosal Antibodies Against Drug-Resistant GonorrheaAn mRNA-Lipid Nanoparticle Platform Encoding the Conserved Outer Membrane Protein BamA Elicits Broadly Cross-Reactive Systemic and Mucosal Antibodies Against Antimicrobial-Resistant Neisseria gonorrhoeae.

Preprint

1 week ago • bioRxiv : the preprint server for biology

Peptides change lipid nanoparticles and improve gene delivery to lung cells without serumPeptide additives reprogram the lipid nanoparticle corona and enhance gene delivery in a serum-free environment for lung epithelium.

Preprint

2 days ago • Marine biotechnology (New York, N.Y.)

A Reliable Method to Deliver Gene Editing Tools and Instructions into Fish EmbryosA Reproducible Electroporation Strategy for CRISPR-Cas9 RNP and mRNA Delivery in Fish Embryos.

Article

5 days ago • Advances in colloid and interface science

Using tiny fat-based carriers to deliver genetic material for protecting plants and crops by applying medical nanotechnology ideasLipid nanocarriers for nucleic acid delivery in plants and crop protection: bridging nanomedicine concepts with agricultural applications.

Article

5 days ago • DNA and cell biology

Current and Future Advances in Using Molecular Replacement to Treat DiseasesMolecular Restoration Through Replacement Therapies: Current Advances and Future Directions in Treating Diseases.

Article

1 week ago • Journal of controlled release : official journal of the Controlled Release Society

Physical factors to consider when designing viruses and lipid nanoparticles for CRISPR genome editingBiophysical considerations for designing viruses, lipid nanoparticles and virus-like particles for CRISPR-based genome editing.

Article

1 week ago • British journal of pharmacology

Immediate allergic and widespread inflammation effects of Comirnaty in pigs linked to spike protein mRNA and increased inflammatory signalsAcute anaphylactic and multiorgan inflammatory effects of Comirnaty in pigs: evidence of spike protein mRNA transfection and paralleling inflammatory cytokine upregulation.

1 week ago • Drug metabolism and bioanalysis

Using Tiny Fat Particles to Improve Diabetes TreatmentLipid Nanoparticles: A New Frontier in Diabetes Treatment.

2 weeks ago • Journal of controlled release : official journal of the Controlled Release Society

A ready-to-use delivery system targeting specific immune cells for personalized mRNA cancer vaccines with strong immune response in primatesNanoReady: A ready-made DC-selective delivery platform for personalized mRNA cancer vaccines with strong NHP immunogenicity.

2 weeks ago • Journal of immunology (Baltimore, Md. : 1950)

T-cell microRNA-155 influences response to tumor-targeting mRNA vaccines in a mouse model of acute leukemiaT-cell miR-155 regulates the response to tumor-specific mRNA vaccines in a murine model of acute myeloid leukemia.

2 weeks ago • medRxiv : the preprint server for health sciences

COVID-19 mRNA Vaccines May Lower the Risk of Guillain-Barré Syndrome in a Large Long-Term StudyCOVID-19 mRNA Vaccination Reduces Guillain-Barré Syndrome Risk: Evidence from a Large Longitudinal Cohort Study.

3 weeks ago • Molecular cell

SMD2 recognizes RNA modifications to control mRNA processing and support tumor growthSMD2 reads pseudouridines to regulate mRNA splicing and promote tumorigenesis.

3 weeks ago • Journal of controlled release : official journal of the Controlled Release Society

Improved methods for delivering RNA to tissues and cells outside the liverAdvances in RNA delivery to extrahepatic tissues and cells.

3 weeks ago • Journal of controlled release : official journal of the Controlled Release Society

Design and early testing of non-viral, non-fat-based nanoparticles for RNA treatmentsNon-viral and non-lipid nanoparticles for RNA therapeutics: Design, applications, and preclinical studies.

3 weeks ago • Journal of controlled release : official journal of the Controlled Release Society

A new mRNA vaccine targeting two cancer markers removes liver cancer in miceA novel bivalent neoantigen vaccine based on mRNA-loaded lipid nanoparticles eradicates hepatocellular carcinoma in mice.

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