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3 weeks ago • Drug testing and analysis

Making and analyzing two LSD-related compounds (1D-LSD and 1T-LSD) and how to tell them apartSynthesis and Analytical Characterization of 1-(1,2-Dimethylcyclobutane-1-Carbonyl)-Lysergic Acid Diethylamide (1D-LSD) and Differentiation From 1-(Thiophene-2-Carbonyl)-LSD (1T-LSD).

📖 Top 30% JournalArticle

3 weeks ago • Life (Basel, Switzerland)

Safety and clinical effects of psychedelics across different use patternsPsychedelic Safety and Clinical Outcomes Across Exposure Patterns: A Structured Narrative Review.

📖 Top 30% JournalArticle

3 weeks ago • Psychopharmacology

Ketamine’s effectiveness and side effects in moderate to severe obsessive-compulsive disorderEfficacy and tolerability of ketamine in moderate to severe obsessive-compulsive disorder: a systematic review.

📖 Top 20% JournalArticle

3 weeks ago • Journal of neurophysiology

Brainwave Study of Antidepressant Effects of Ketamine Forms and Their Breakdown Products in MonkeysAn EEG-Based Evaluation of Antidepressant Effects of Ketamine Enantiomers and Metabolites in Monkeys.

Article

3 weeks ago • CNS drugs

New Drug Developments for Treating Unipolar Mood Disorders Using Different ApproachesNext-Generation Pharmacotherapies for Unipolar Mood Disorders: A Leading Article on Phase II/III Drug Development Across Diverse Mechanisms.

Article

3 weeks ago • Psychopharmacology

Comparing high doses of THC, psilocybin, and placebo during a classic psychedelic therapy sessionPilot study comparing the effects of high dose THC to high dose psilocybin and placebo in the set and setting of a classic psychedelic therapy session.

📖 Top 20% JournalArticle

3 weeks ago • The Journal of legal medicine

Comparing State Rules to Find the Best Way to Regulate PsilocybinToward an Optimal Framework for Psilocybin Regulation: A Comparison of State Regulatory Approaches Across Key Dimensions.

Article

3 weeks ago • Chemical senses

How a psychedelic drug changes mice’s sense of smell and searching behaviorThe impact of a psychedelic drug on olfactory search behavior by mice.

📖 Top 30% JournalArticle

3 weeks ago • Journal of psychopharmacology (Oxford, England)

Psilocybin changes rats' natural behaviors depending on the dose, beyond just causing head twitchesBeyond head-twitch response: Acute psilocybin affects spontaneous behaviors in rats in a dose-dependent manner.

Article

3 weeks ago • Journal of psychopharmacology (Oxford, England)

Salvinorin A in humans: How it is processed, affects the body, and its safetySalvinorin A in humans: A systematic review of pharmacokinetics, pharmacodynamics, and safety.

Article

3 weeks ago • Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater

S-ketamine as a treatment for suicidal thoughts and hard-to-treat depression in teens with early psychosisCase report of S-ketamine as treatment option for suicidal ideation and treatment-resistant depression in adolescents with early-onset psychosis.

📖 Top 50% JournalArticle

3 weeks ago • Journal of pain research

One-Day IV Ketamine Treatment for Fibromyalgia with Long-Term Follow-Up in a Large Patient GroupA Single-Day Intravenous Ketamine Infusions for Fibromyalgia, a Large Retrospective Study with a Long-Term Assessment.

📖 Top 30% JournalArticle

3 weeks ago • Academic forensic pathology

Serious Self-Harm During Psilocybin Use: Is It Suicide or Not?Complex Fatal Self-Harm Under Psilocybin Intoxication: Suicidal Manner of Death or Not?

Article

4 weeks ago • Journal of studies on alcohol and drugs

Negative Effects Described in Reports of Recreational Psychedelic and Non-Psychedelic Drug UseAdverse Effect-Related Language in Recreational Psychedelic and non-Psychedelic Substance Experience Reports.

📖 Top 30% JournalArticle

4 weeks ago • The Journal of pharmacology and experimental therapeutics

Body Awareness Effects of Modified Lysergamides in Rats Linked to Serotonin Receptor Binding and Breakdown into LSDInteroceptive effects of N1-substituted lysergamides in rats: Role of agonist affinity at 5-hydroxytryptamine receptors and in vivo metabolism to lysergic acid diethylamide.

Article

4 weeks ago • Frontiers in public health

Key public health needs for psychedelics: education, trained workers, and information in a fast-changing environmentPriorities for public health preparedness for psychedelics: education, workforce readiness, and strategic information needs in a rapidly changing landscape.

📖 Top 20% JournalArticle

4 weeks ago • Frontiers in psychiatry

Challenges and priorities in combining methods to assess psychedelic-assisted therapyMethodological fragmentation and integration priorities in psychedelic-assisted therapy assessment: a scoping review.

📖 Top 20% JournalSystematic Review

4 weeks ago • Neuroscience of consciousness

Low-dose LSD changes how people see visuals without affecting visual contrast processingLow-dose lysergic acid diethylamide alters subjective visual perception but not visual contrast surround suppression.

🎖️ Top 10% JournalArticle

4 weeks ago • World journal of methodology

How Different Anesthetics (Propofol, Etomidate, Ketamine) Affect Seizure Length and Thinking Recovery During Electroconvulsive TherapyImpact of different anesthetic agents (propofol, etomidate, ketamine) on seizure duration and cognitive recovery in electroconvulsive therapy.

Article

1 month ago • Npj mental health research

Using ketamine or esketamine with psychotherapy to manage depression in adultsA scoping review: ketamine or esketamine when used to assist psychotherapy or in combination with psychotherapy for the management of depression in adults.

Article

1 month ago • ACS medicinal chemistry letters

Improving new psychedelic treatments by targeting specific brain receptors with precise inhaled doses and better 5-MeO-DMT use methodsAdvancing Next-Generation Psychedelic Therapeutics through Selective 5‑HT2A Activation, Precision Aerosol Delivery, and Optimized 5‑MeO-DMT Treatment Paradigms.

📖 Top 30% JournalEditorial

1 month ago • Military medicine

Combining Ketamine and Relaxation Training to Manage Chronic Pain: A Case Study at Walter Reed Medical CenterIntegrating Ketamine and Autogenic Training for Chronic Pain: A Case Study at Walter Reed National Military Medical Center.

📖 Top 50% JournalArticle

1 month ago • bioRxiv : the preprint server for biology

Ultrasound boosts ketamine's effects on brain activityUltrasonic potentiation of ketamine neuromodulation.

Preprint

1 month ago • Progress in neuro-psychopharmacology & biological psychiatry

Changes in memory system activity and adjustment during psychedelic therapyFrom network destabilisation to adaptive reconfiguration: A hippocampal longitudinal Axis model of psychedelic therapy.

Article

1 month ago • Nature

Psychedelics make brain activity match the surrounding situationPsychedelics align brain activity with context.

Article

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