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2 weeks ago • Asian journal of psychiatry

Ketamine's actions in major and treatment-resistant depression: Could changes in brain network organization explain its effects?Ketamine's mechanisms of action in major depressive disorder and treatment-resistant depression: Is brain topological change a candidate convergent systems-level pathway?

📖 Top 20% JournalArticle

2 weeks ago • Psychopharmacology

How psychedelic drugs affect timing behavior and brain circuits in miceInvestigation of the pharmacological and circuit basis for psychedelic drug effects on interval timing in mice.

📖 Top 20% JournalArticle

2 weeks ago • Psychopharmacology

Serotonin 1B receptors on forebrain excitatory neurons may help reduce anxiety after psilocybin in miceSerotonin 1B receptors expressed on forebrain excitatory neurons mediate the post-acute anxiolytic response to psilocybin in mice.

📖 Top 20% JournalArticle

2 weeks ago • Progress in neuro-psychopharmacology & biological psychiatry

Ketamine reduces learned defensive reactions and increases brain plasticity proteins in flatworms recalling unpleasant memoriesKetamine administration reduced conditioned defensive behaviour and upregulated protein expression associated with neuroplasticity in a planarian model of aversive memory reactivation.

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2 weeks ago • Psychopharmacology

How common are MDMA aftereffects, what are their features, and how do people cope with themWhat goes up must comedown: prevalence rates, characteristics, and coping strategies concerning MDMA aftereffects.

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2 weeks ago • Psychopharmacology

How Combining Meditation and Psychoactive Substances Relates to Well-BeingBeyond psychedelic exceptionalism: how people combine meditation with psychoactive substances, and how this relates to well-being.

📖 Top 20% JournalArticle

2 weeks ago • Molecules (Basel, Switzerland)

Anxiety- and depression-reducing effects of α,α-Trehalose, a natural compound found in Psilocybe cubensisPreclinical Anxiolytic- and Antidepressant-like Effects of α,α-Trehalose, a Bioactive Compound Identified in Psilocybe cubensis.

📖 Top 20% JournalArticle

2 weeks ago • Journal of psychoactive drugs

How Psychedelic Drug Use Relates to Romantic Relationship HealthPsychedelic Drug Use and Romantic Relationship Functioning.

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2 weeks ago • Brain and behavior

Body Movement Experiences After Taking Different Amounts of Psilocybin in Healthy PeopleAfter the Trip: A Qualitative Study of Healthy Individuals' Motor Experiences Following Different Doses of Psilocybin.

📖 Top 20% JournalArticle

2 weeks ago • L'Encephale

French Mental Health Workers' Views on Psychedelic Drugs: A National SurveyFrench psychiatric caregivers' perceptions of psychedelics: A national survey.

📖 Top 50% JournalArticle

2 weeks ago • Nature neuroscience

Specific brain receptors in deep thinking neurons support psilocybin’s brain plasticity effects but not its hallucinogenic effects5-HT2A receptors in layer 5 pyramidal neurons mediate the neuroplastic but not the hallucinogenic effects of psilocybin.

🥇 Top 1% JournalArticle

2 weeks ago • Neuropsychiatric disease and treatment

Ketamine and Esketamine for Sudden Suicidal Crises: What We Know, Their Limits, and a New Recovery ApproachKetamine and Esketamine in Acute Suicidal Presentations: Evidence, Limits, and a Conceptual Recovery-Enabling Downstaging Framework.

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2 weeks ago • Epigenetics

Changes in blood DNA methylation over time after ketamine-assisted therapy in major depressionLongitudinal peripheral DNA methylation remodeling following ketamine-assisted psychotherapy in major depressive disorder.

📖 Top 20% JournalArticle

2 weeks ago • Frontiers in psychiatry

Long-lasting ketamine abstinence after ibogaine treatment: a case reportCorrection: Sustained abstinence in severe ketamine use disorder following ibogaine treatment case report.

📖 Top 20% JournalPublished Erratum

2 weeks ago • Frontiers in pharmacology

Using flashing light to study and test how psilocybin affects the brainStroboscopic light stimulation as a controllable probe of the psilocybin state: a mechanistic framework and a falsifiable prediction.

📖 Top 20% JournalArticle

2 weeks ago • The oncologist

Personal Control and Psychedelic Therapy in Advanced Cancer: Ethical Lessons from Patient CasesAspirational autonomy and psychedelic-assisted therapy in advanced cancer: ethical lessons from clinical cases.

🥉 Top 5% JournalArticle

2 weeks ago • Paediatric drugs

Drugs for Treating Acute Stress and Preventing or Treating PTSD in Children and Teens: A ReviewPharmacological Interventions for Acute Stress Disorder and for the Prevention and Treatment of Post-traumatic Stress Disorder in Children and Adolescents: A Narrative Review.

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2 weeks ago • BMC medical ethics

Feeling Safe: Understanding Vulnerability in (Es)Ketamine TreatmentFeeling safe: an empirical-ethical analysis of vulnerability in (es)ketamine treatment.

📖 Top 20% JournalArticle

2 weeks ago • Frontiers in public health

Creating a system to evaluate ways to reduce psychedelic harm at events using mixed research methodsDesigning evaluation infrastructure for psychedelic harm reduction at events: a methodological framework with formative mixed-methods field application.

📖 Top 20% JournalArticle

2 weeks ago • European journal of pharmacology

Ibogaine may support brain cell repair and flexibility by changing cell metabolismExtracellular flux analysis and proteomic profiling indicate ibogaine promotes synaptic plasticity and neural repair by a metabolic preconditioning mechanism.

📖 Top 20% JournalArticle

2 weeks ago • Advances in therapy

Ibogaine as a Treatment for Substance Use DisordersIbogaine for Substance Use Disorders.

📖 Top 20% JournalArticle

2 weeks ago • ACS pharmacology & translational science

Understanding the Gap Between Drug Effects and Personal Experience in Psychedelic ResearchStudying the Molecule, Assuming the Experience: The Pharmacology-Experience Asymmetry Framework for Psychedelic Research.

📖 Top 20% JournalArticle

2 weeks ago • Canadian family physician Medecin de famille canadien

Therapy Using Psychedelic Drugs: A New ApproachPsychedelic-assisted psychotherapy: Emerging paradigm.

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2 weeks ago • Health affairs scholar

Who qualifies for psilocybin therapy? A secret shopper study of Oregon mushroom service centers"Am I a candidate for magic mushrooms?" A mystery shopper study of Oregon psilocybin service centers.

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3 weeks ago • Social science & medicine (1982)

How Talking About Trauma Helps and Limits Healing in Psychedelic Experiences'The only way out is through': The flexibility and limits of trauma discourse in psychedelic contexts.

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3 weeks ago • Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists

Ketamine’s effectiveness in hard-to-treat depression may vary by depression type and childhood trauma historyKetamine administered biomedically or as psychedelic-assisted therapy in treatment-resistant depression: Differing efficacy based on depressive subtype or presence of childhood trauma?

📖 Top 50% JournalArticle

3 weeks ago • International journal of medicinal mushrooms

Lion's Mane Mushroom Root May Reduce the Risk of Ketamine AbuseCulinary-Medicinal Lion's Mane Mushroom Hericium erinaceus (Agaricomycetes) Mycelium Mitigates Ketamine Abuse Potential.

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3 weeks ago • Psychopharmacology

Short-term anxiety-causing effects of psilocybin and a related compound in male and female ratsAcute anxiogenic effects of psilocybin and the related tryptamine, norbaeocystin, in male and female rats.

📖 Top 20% JournalArticle

3 weeks ago • Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

Boosting cGMP signaling with psilocybin reduces head twitch behavior and changes synapse proteins while keeping antidepressant effectsEnhancing cGMP signaling with psilocybin reduces head twitch and restructures the synaptic proteome while maintaining antidepressant response.

🥉 Top 5% JournalArticle

3 weeks ago • Molecular neurobiology

Ayahuasca weakens fear memory and quickly changes brain structure in memory and decision areasAyahuasca Impairs Fear Memory Reconsolidation and Promotes Rapid Structural Plasticity in the Hippocampus and Prelimbic Cortex.

🎖️ Top 10% JournalArticle

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