Latest Longevity & Aging Research Papers (Past Year) | Page 3

4 days ago • Cell death and differentiation

Shoc2 controls new lymphatic vessel growth by reducing immune responses linked to mTORC1Signaling scaffold Shoc2 regulates lymphangiogenesis by suppressing mTORC1-mediated IFN responses

🥇 Top 1% JournalArticle

4 days ago • Aging

Developing practical ways to address human aging (12th ARDD meeting, 2025)Toward actionable interventions in human aging (12th ARDD meeting, 2025)

📖 Top 20% JournalArticle

4 days ago • Journal of biochemical and molecular toxicology

How Cell Cleaning Processes Help and Harm in Heart Muscle DiseaseFrom Defence to Dysfunction: The Dual Role of Autophagy and Mitophagy in Cardiomyopathy

📖 Top 30% JournalArticle

4 days ago • Journal of advanced research

How the lymphatic system affects healing, cancer, and agingFrom repair to disease: lymphatic contributions to regeneration, cancer and ageing

🥉 Top 5% JournalArticle

4 days ago • Cytokine & growth factor reviews

The two roles of MIF in aging and cell agingDual role of MIF in aging and cellular senescence

🥉 Top 5% JournalArticle

4 days ago • Cell chemical biology

Different ways huntingtin protein clumps with varying polyQ lengths disrupt cell cleanupDistinct autophagy impairment mechanisms of huntingtin aggregates with different polyQ lengths

🥉 Top 5% JournalArticle

4 days ago • Critical reviews in food science and nutrition

Ginsenosides in food: their production, health benefits, and use for longer lifeDietary ginsenosides for longevity: from biosynthesis and bioactive potential to functional food applications

🥉 Top 5% JournalArticle

4 days ago • Apoptosis : an international journal on programmed cell death

SIRT1-controlled removal of damaged mitochondria reduces fat-induced cell death in diabetic kidney diseaseSIRT1-regulated mitophagy mitigates lipotoxicity-induced ferroptosis in diabetic kidney disease

🥉 Top 5% JournalArticle

4 days ago • Phytotherapy research : PTR

Hesperidin helps heal damaged nerves by activating cell recycling and preventing cell death through the STAT3/Bcl-2 pathwayHesperidin Promotes Peripheral Nerve Repair by Inducing Autophagy and Inhibiting Apoptosis via the STAT3 /Bcl‐2 Pathway

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4 days ago • GeroScience

Faster biological aging is linked to quicker development of multiple health conditionsAccelerated biological aging is associated with faster multimorbidity progression: a UK biobank study

🎖️ Top 10% JournalArticle

4 days ago • Chemical communications (Cambridge, England)

Fluorescent probes for tracking changes in mitochondrial thickness during mitophagySilicon rhodamine-based fluorescent probes for monitoring mitochondrial viscosity dynamics during mitophagy

📖 Top 20% JournalArticle

5 days ago • Materials today. Bio

Tiny mitochondria outside cells change the wound environment by removing harmful molecules without entering cellsExtracellular biogenic nanoscale mitochondria reprogram the wound microenvironment via ROS scavenging independent of cellular uptake

🥉 Top 5% JournalArticle

5 days ago • Genes & diseases

Interaction between cell recycling and iron-related cell death in diabetesCrosstalk between autophagy and ferroptosis in diabetes

🎖️ Top 10% JournalArticle

5 days ago • Genes & diseases

The role of cell aging and possible treatments in spine disc breakdownThe role and potential therapeutic intervention of cellular senescence in intervertebral disc degeneration

🎖️ Top 10% JournalArticle

5 days ago • Journal of cellular and molecular medicine

Molecular profiles reveal aging signs in bone-forming cells from Osteogenesis Imperfecta that are reduced by 4-PBAOMICS Profiling Identifies Signatures of Senescence in Osteogenesis Imperfecta Osteoblasts Counteracted by 4‐PBA

📖 Top 20% JournalFulltext (Open License)Article

5 days ago • Journal of cellular and molecular medicine

How DAPK1 Inactivates Parkin to Increase Nerve Cell Damage by Triggering MITOL-Dependent BreakdownDAPK1 ‐Mediated Parkin Inactivation Enhances Neurotoxicity via MITOL ‐Dependent Degradation

📖 Top 20% JournalFulltext (Open License)Article

5 days ago • Frontiers in endocrinology

Rethinking the adrenal stress index by studying immune cell-linked resistance to stress hormonesBeyond adrenal fatigue: reframing the adrenal stress index through neutrophil-mediated glucocorticoid resistance

🎖️ Top 10% JournalFulltext (Open License)Article

5 days ago • Frontiers in molecular biosciences

Gene activity changes from chlorogenic acid and taurine treatment reveal how human skin cells ageTranscriptomic profiling of chlorogenic acid and taurine treatment in human skin cells provides insights into cellular senescence mechanisms

📖 Top 20% JournalFulltext (Open License)Article

5 days ago • Journal of Alzheimer's disease : JAD

Time-Restricted Eating and Its Potential in Alzheimer's Disease: A Research InvitationTime-restricted eating in Alzheimer's disease (TREAD): A call for research

📖 Top 20% JournalArticle

5 days ago • Autophagy

Phase separation of C19orf12 controls BNIP3 protein quality and supports mitochondrial cleanup in neuronsPhase separation of C19orf12 regulates BNIP3 protein quality control and maintains neuronal mitophagy

🥈 Top 2% JournalArticle

5 days ago • Nature communications

ASO therapy may reverse DNA damage, 3D genome structure problems, and cell aging caused by NOTCH2NLC GGC repeat expansionASO therapy rescues NOTCH2NLC GGC repeat expansion-induced genomic damage, 3D chromatin structural abnormalities, and senescence

🥈 Top 2% JournalArticle

5 days ago • Journal of Alzheimer's disease : JAD

Shared Genetic Factors Linked to Muscle Loss and Alzheimer's DiseaseUncovering polygenic and local genetic overlap between sarcopenia and Alzheimer's disease

📖 Top 20% JournalArticle

5 days ago • Biochemistry

Mitochondrial Ubiquitination as a Key Signal Balancing Mitochondrial Cleanup, Inflammation, and Cell DeathMitochondrial Ubiquitination as a Signaling Hub: Balancing Mitophagy, Inflammation, and Cell Death

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5 days ago • Frontiers in immunology

Rapamycin reduces gut inflammation caused by HLA-B27 and changes gut bacteria in a model of spondyloarthritisRapamycin treatment ameliorates HLA-B27-mediated gut inflammation and alters the microbiome in experimental spondyloarthritis

🥉 Top 5% JournalFulltext (Open License)Article

5 days ago • Journal of neural transmission (Vienna, Austria : 1996)

Genetic and environmental factors linked to ParkinsonismGenetic and environmental risk factors of Parkinsonism

📖 Top 20% JournalArticle

5 days ago • Journal of neurochemistry

L-Leucine boosts cell cleaning processes to reduce plaques in an Alzheimer's mouse modelL‐Leucine Upregulates Lysosomal Biogenesis and Autophagy to Lower Plaques in 5XFAD Mouse Model of Alzheimer's Disease

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5 days ago • Proceedings of the National Academy of Sciences of the United States of America

Microvesicle release may cause repeated breakdown of damaged heart cell parts and increased inflammation in sepsis-related heart problemsMicrovesicle release drives cycles of mitophagy flux disruption and inflammatory amplification in sepsis-induced myocardial dysfunction

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5 days ago • Acta biomaterialia

Smart delivery of engineered cell messengers carrying peptides to break down a-synucleinIntelligent delivery of autophagy-targeting chimeric peptides by engineered exosomes for the degradation of a-synuclein

🥉 Top 5% JournalArticle

6 days ago • Journal of lipid research

Watching fat breakdown in living mice using a special fluorescent reporterIn vivo visualization of lipophagy dynamics using the tfLiveDrop reporter mice

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6 days ago • Neuroscience letters

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