Latest mRNA Technology Research Papers | Page 2 | OpenScience.ink

1 week ago • Small science

New Developments in Nano-Sized Drug Carriers Made from PolyethyleneimineAdvances in Polyethyleneimine-Derived Nanoformulations.

🥉 Top 5% JournalArticle

1 week ago • Animals : an open access journal from MDPI

A New ORFV F1L mRNA Vaccine: Development, Immune Response, and Comparison with a Commercial Live VaccineAn ORFV F1L mRNA Vaccine Candidate: Preparation, Immunogenicity, and Comparison with a Commercial Live Vaccine.

📖 Top 30% JournalArticle

1 week ago • Molecular therapy. Oncology

Oncolytic virus changes tumor environment to improve HPV-positive tumor vaccine targeting HPV16 proteinsOncolytic virus-mediated remodeling of tumor microenvironment enhances efficacy of an HPV16 E6/E7 mRNA vaccine in an HPV-positive tumor.

🎖️ Top 10% JournalArticle

1 week ago • Pharmaceutics

Improving delivery of therapeutic mRNA to the lungs to prevent lung scarringOptimization of Therapeutic modRNA Delivery to the Lung for Prevention of Pulmonary Fibrosis.

📖 Top 20% JournalArticle

1 week ago • International journal of molecular sciences

COVID-19 mRNA Vaccines Linked to Lower Immune Cell Death in Patients with Solid TumorsSARS-CoV-2 mRNA Vaccination Induces Reduced T-Cell Apoptosis in Patients with Solid Tumors.

📖 Top 20% JournalArticle

1 week ago • Advances in medical sciences

How RNA chemical changes relate to cancer growth and resistance to platinum drugsEpitranscriptomic regulation in the progression of cancer and platinum resistance.

📖 Top 30% JournalArticle

1 week ago • Journal of virology

Testing a vaccine targeting multiple proteins of EEHV1A in Asian elephantsEvaluation of a multiantigen mRNA vaccine against EEHV1A in Asian elephants.

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1 week ago • Pharmaceutics

Immune responses to PEG in mRNA lipid vaccines show changes across the populationAnti-PEG Immunogenicity of mRNA-LNP Vaccines in Humans: Evidence for Population-Level Changes in the Anti-PEG Antibody Repertoire.

📖 Top 20% JournalArticle

1 week ago • Current issues in molecular biology

Creating and Testing a Protected mRNA for Human Growth HormoneDesign, Synthesis, and Proof-of-Concept Bioassay of an Encapsulated mRNA for Human Growth Hormone.

📖 Top 30% JournalArticle

1 week ago • International journal of molecular sciences

Molecular methods for RNA and epigenome editing therapies beyond permanent gene changesBeyond Permanent Genome Editing: Molecular Delivery Strategies for RNA Editing and Epigenome-Editing Therapeutics.

📖 Top 20% JournalArticle

1 week ago • Current pharmaceutical design

Using Fat-Based Nanoparticles for Skin Cancer Treatment: Drug Delivery, Gene Therapies, and Clinical ProgressHarnessing Lipid-Based Nanocarriers for Skin Cancer Therapy: A Comprehensive Review of Drug Delivery, Gene-Based Strategies, and Clinical Translation.

📖 Top 50% JournalArticle

1 week ago • Critical reviews in oncology/hematology

Use of mRNA Vaccines in Immune Treatment for Head and Neck Cancer: Progress and ChallengesApplication of mRNA Vaccines in Head and Neck Cancer Immunotherapy: Current Progress and Challenges.

🎖️ Top 10% JournalArticle

1 week ago • Pharmaceutics

Analysis and Stability of RNA-Based VaccinesAnalytical Characterization and Stability Assessment of RNA-Based Vaccines.

📖 Top 20% JournalArticle

1 week ago • Molecular therapy. Nucleic acids

Testing lipid nanoparticle vaccine helpers with different PEG and phospholipid types in primatesEvaluation of lipid nanoparticle adjuvants with different PEG lipid ratios and phospholipid modifications in non-human primates.

🥉 Top 5% JournalArticle

1 week ago • Clinics and research in hepatology and gastroenterology

Personalized CRISPR gene editing tailored for rare genetic liver diseasesFrom one-size-fits-all to on-demand: personalized crispr gene editing for rare genetic liver diseases.

📖 Top 30% JournalArticle

1 week ago • Vaccine

Immune response, side effects, and safety of seven COVID-19 vaccines given as fifth or later booster doses in healthy adultsThe Platform trial In COVID-19 priming and BOOsting (PICOBOO): The immunogenicity, reactogenicity and safety of seven licensed COVID-19 vaccines delivered as fifth dose or subsequent boosters in immunocompetent adults.

📖 Top 20% JournalArticle

1 week ago • Molecular therapy. Nucleic acids

Lipid nanoparticles help deliver mRNA to different cell types inside the retinaLipid nanoparticles enable mRNA delivery to diverse cell types of the inner Retina.

🥉 Top 5% JournalArticle

1 week ago • Journal of virology

First signs that an mRNA vaccine can protect young elephants naturally infected with EEHV1AFirst evidence of clinical protection from an EEHV1A mRNA vaccine in naturally infected juvenile elephants.

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1 week ago • Pharmaceutics

Using Artificial Intelligence to Design and Develop Nanomedicine from Drug Formulation to Clinical UseArtificial Intelligence-Driven Nanomedicine: From Drug Formulation and Nanocarrier Design to Clinical Translation.

📖 Top 20% JournalArticle

1 week ago • Biomolecules

Shared Tumor-Specific Targets Based on Genetic Sequences for Ready-Made mRNA Cancer Vaccines Matched to Patient Immune Types Across Multiple CancersSequence-Anchored Shared Tumor-Specific Epitopes for Pre-Manufactured HLA-Matched mRNA Cancer Vaccine Libraries: A Pan-Cancer Framework.

🎖️ Top 10% JournalArticle

1 week ago • Vaccines

Minicircle DNA Vaccines and How They Improve Delivery and Protein Production for Advanced ImmunizationMinicircle DNA Vaccines: Overcoming Delivery and Expression Barriers in Next-Generation Immunization.

📖 Top 20% JournalArticle

1 week ago • Vaccines

Fast measurement of mRNA vaccine cap quality using precise RNA cutting and improved chromatographyRapid LC-MS Quantification of mRNA Vaccine Capping Efficiency via High-Specificity RNase H Cleavage and Metal Adduct Suppressed Chromatography.

📖 Top 20% JournalArticle

1 week ago • ACS nano

Understanding the Roles of Different Parts in mRNA Lipid NanoparticlesDecoding the Functional Roles of Individual Components in mRNA Lipid Nanoparticles.

🥈 Top 2% JournalArticle

1 week ago • Advanced materials (Deerfield Beach, Fla.)

Using Continuous Microfluidics to Explore and Build Lipid NanostructuresNavigating Lipid Nanostructure Design Space Through Continuous Microfluidic Automation.

🥇 Top 1% JournalArticle

1 week ago • Journal of chemical theory and computation

Branched ionizable fats cause cholesterol clustering and pH-related changes in lipid nanoparticlesBranched Ionizable Lipids Drive Cholesterol Domain Formation and pH-Dependent Remodeling in Lipid Nanoparticles.

🎖️ Top 10% JournalArticle

1 week ago • Diseases (Basel, Switzerland)

Development of mRNA Vaccines for Diseases Other Than COVID-19: A Review of Clinical and Laboratory StudiesFrom Pandemic Innovation to Platform Diversification: A Systematic Review of Clinical and Preclinical Development of Non-SARS-CoV-2 mRNA Vaccines.

📖 Top 20% JournalArticle

1 week ago • Journal of controlled release : official journal of the Controlled Release Society

Physical factors to consider when designing viruses and lipid nanoparticles for CRISPR genome editingBiophysical considerations for designing viruses, lipid nanoparticles and virus-like particles for CRISPR-based genome editing.

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1 week ago • American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

CD8 T-cell mRNA vaccines targeting viral proteins to prevent BK polyomavirus disease after kidney transplantDesigning CD8 T-cell mRNA vaccines targeting the viral large T antigen to prevent BK polyomavirus disease after kidney transplantation.

🥉 Top 5% JournalArticle

1 week ago • ACS applied materials & interfaces

Carefully Designed Polymer Carriers for Effective PTEN mRNA Treatment of Non-Small Cell Lung CancerPrecisely Engineered Block Copolymers for Efficient PTEN mRNA Therapy of Non-Small Cell Lung Cancer.

🎖️ Top 10% JournalArticle

1 week ago • Vaccines

A new tiny particle system that improves poultry vaccinesA Novel Effective Nanoadjuvant System for Poultry Vaccines.

📖 Top 20% JournalArticle

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