OpenScience.ink

1 week ago • Journal of pharmaceutical and biomedical analysis

Using higher temperatures to improve and speed up CRISPR detection of SARS-CoV-2 and its Omicron variantLeveraging high temperature for enhanced and faster detection of SARS-CoV-2 and its Omicron variant with CRISPR-AsCas12a.

📖 Top 30% JournalArticle

2 weeks ago • Analytical methods : advancing methods and applications

Highly sensitive detection of Staphylococcus aureus using a programmable DNA sensor and CRISPR amplificationA programmable aptamer-triggered B-PER/CRISPR cascade amplification platform for ultrasensitive detection of Staphylococcus aureus.

📖 Top 50% JournalArticle

2 weeks ago • Human gene therapy

Using Mobile DNA and CRISPR-Based Tools Beyond Viruses for Genome EditingBeyond Viruses: Transposons and CRISPR-Programmable Nonviral Systems for Genome Engineering.

📖 Top 20% JournalArticle

3 weeks ago • Blood research

Targeting a specific viral protein triggers inflammatory cell death and may offer a new treatment for acute myeloid leukemiaCorrespondence on: "Targeting the HERV-K102 envelope elicits pyroptosis and represents a novel therapeutic strategy for acute myeloid leukemia".

📖 Top 30% JournalComment

3 weeks ago • Journal of visualized experiments : JoVE

Computer Modeling of Gene Editing to Restore Factor VII Production in Inherited DeficiencyIn Silico CRISPR Restoration of F7 Promoter Activity in Hereditary Factor VII Deficiency.

📖 Top 50% JournalVideo-Audio Media

1 week ago • Stem cell research

Creating Stem Cell Lines for Spinocerebellar Ataxia 27B and Matching ControlsGeneration of Spinocerebellar Ataxia 27B iPSC Lines and Isogenic Controls.

📖 Top 50% JournalArticle

3 weeks ago • Physical activity and nutrition

Combining gene editing and exercise to improve function in ALSIntegrative ALS therapy: gene targeted therapy by base editing and potential exercise rehabilitation as synergistic strategies for functional recovery.

📖 Top 50% JournalArticle

3 weeks ago • Stem cell research

Creating a human stem cell line with a specific PKP2 gene mutation using precise DNA editingGeneration of a PKP2 (c.1171-2 A > G) mutant human embryonic stem cell line using adenine base editing.

📖 Top 50% JournalArticle

5 days ago • Methods in molecular biology (Clifton, N.J.)

Light-Controlled Method to Regulate the p53 Cell Stress PathwayOptogenetic Tool for Controlling p53 Signaling Pathway.

📖 Top 50% JournalArticle

1 week ago • Methods in molecular biology (Clifton, N.J.)

Creating Melanoma Cell Lines with Specific Genes Disabled Using CRISPR-Cas9Generation of Functional Gene Knockout Melanoma Cell Lines by CRISPR-Cas9 Gene Editing.

📖 Top 50% JournalArticle

1 week ago • Methods in molecular biology (Clifton, N.J.)

Reducing Long Noncoding RNAs Using Cas13dCas13d-Mediated Knockdown of Long Noncoding RNAs.

📖 Top 50% JournalArticle

2 weeks ago • Methods in molecular biology (Clifton, N.J.)

Using CRISPR to Change Genes and Gene Activity in Ewing SarcomaGenetic and Epigenetic Manipulation Using CRISPR Techniques in Ewing Sarcoma.

📖 Top 50% JournalArticle

3 weeks ago • Die Ophthalmologie

Gene-based treatments for Stargardt disease[Genetic therapies for Stargardt disease].

English Abstract

3 weeks ago • bioRxiv : the preprint server for biology

Genome-wide activation map of surface protein levels in human helper T cellsA genome-wide CRISPR activation map of surface protein expression in human CD4 T cells.

Preprint

3 weeks ago • bioRxiv : the preprint server for biology

A gene-editing method for human liver cells allows testing and confirming factors that affect hepatitis B virusA CRISPR-Cas9 platform for primary human hepatocytes enables arrayed screening and in vivo validation of HBV host factors.

Preprint

1 week ago • bioRxiv : the preprint server for biology

A new mouse model for a high-risk age-related macular degeneration gene variant, ARMS2 A69SA new mouse model for a high-risk AMD variant, ARMS2 A69S.

Preprint

1 week ago • bioRxiv : the preprint server for biology

SLC25A28 is a critical weakness in cancers lacking a DNA repair systemSLC25A28 is a synthetic lethal vulnerability in nucleotide excision repair-deficient cancers.

Preprint

1 week ago • bioRxiv : the preprint server for biology

How tRNA Needs Change in Different Tumor EnvironmentsThe adaptive architecture of tRNA dependencies across physiological tumor environments.

Preprint

3 weeks ago • bioRxiv : the preprint server for biology

Genes that help Epstein-Barr virus infect human B cells found using a genome-wide CRISPR screenA Human Genome-wide CRISPR-Cas9 Screen Reveals Host Factors That Support Epstein-Barr Virus B cell infection.

Preprint

3 weeks ago • bioRxiv : the preprint server for biology

How plasmid design affects the stability of end DNA repeats in adeno-associated virus vectorsPlasmid architecture determines the stability of inverted terminal repeats in adeno-associated virus vectors.

Preprint

3 weeks ago • Neuron

A gene delivery system for studying immune cells in the brain across different speciesA cross-species AAV platform for precise microglial interrogation.

Article

1 week ago • Biochemistry

Programmable Genome Detection Using RNA Switch and CRISPR with Visual, Fluorescent, and Glucose Meter Readouts in a Cell-Free SystemProgrammable Genome Sensing with Visual, Fluorescence, and Glucometer Readings: Cell-Free In Vitro Translation Approach Using RNA Switch-CRISPR.

Article

1 week ago • Biochemistry

A DNA Pyramid That Responds to CRISPR-Cas12aA CRISPR-Cas12a-Responsive DNA Tetrahedron.

Article

1 week ago • bioRxiv : the preprint server for biology

Mapping DNA regions that activate, silence, or organize genes using precise deletion editingSystematic mapping of enhancers, silencers, and topological elements with prime editing deletion screens.

Preprint

1 week ago • bioRxiv : the preprint server for biology

Virus-like particles carrying mRNA enable accurate mitochondrial DNA editing in cells and living organismsEngineered mRNA-packaging virus-like particles enable efficient and precise mitochondrial base editing in vitro and in vivo.

Preprint

1 week ago • bioRxiv : the preprint server for biology

Prime editing allows fast testing and understanding of selective MutSβ blockersPrime editing enables high-throughput identification and characterization of selective MutSβ inhibitors.

Preprint

3 weeks ago • bioRxiv : the preprint server for biology

Activation of gene regions by CRISPRa creates lasting chromatin states showing gene-specific memory effectsInduction of hysteretic chromatin states by CRISPRa reveals locus-specific encoding of transcriptional memory.

Preprint

3 weeks ago • bioRxiv : the preprint server for biology

Engineering human immune cells to carry gene editing toolsProgramming primary human T cells to deliver gene editing machinery.

Preprint

3 weeks ago • bioRxiv : the preprint server for biology

Using base editing to map chemical and genetic interactions in the MAPK signaling pathwayPathway-wide base editing charts chemical-genetic interactions in MAPK signaling.

Preprint

3 weeks ago • bioRxiv : the preprint server for biology

Measuring how dCas9 finds DNA to identify what affects guide RNA effectivenessQuantitative profiling of intrinsic dCas9-DNA recognition reveals key determinants of guide RNA performance.

Preprint

← prevpage 5 of 6next →

CRISPR Gene Editing Research Papers