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2 weeks ago • Methods in molecular biology (Clifton, N.J.)

Producing Rice Plants with Only One Set of Genes by Removing a Protein Active in Egg CellsIn Vivo Rice Haploid-Induction System by an Egg Cell-Specific Peptidase Knockout.

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4 weeks ago • Methods in molecular biology (Clifton, N.J.)

Designing Switchable Guide RNAs to Control Gene ActivityDesign of Conditional Guide RNAs for the Logical Regulation of Gene Expression.

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4 weeks ago • Methods in molecular biology (Clifton, N.J.)

Using CRISPRi Between Cells to Build Distributed Genetic CircuitsIntercellular CRISPRi for Distributed Genetic Circuits.

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4 weeks ago • Methods in molecular biology (Clifton, N.J.)

Building a Genetic Switch in Bacteria to Reduce Protein ProductionConstruction of a Tl-CRISPRi Genetic Circuit in Bacteria for Translation-Level Gene Knockdown.

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4 weeks ago • Methods in molecular biology (Clifton, N.J.)

Designing Synthetic Gene Control Systems Using CRISPRi in BacteriaDesign of CRISPRi-Based Synthetic Gene Circuits in Bacteria.

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4 weeks ago • Methods in molecular biology (Clifton, N.J.)

Using CRISPRi Competition to Build Multi-Part Controllers for Managing Resources in Genetic CircuitsHarnessing CRISPRi Competition to Develop Multimodule Controllers for Resource-Aware Circuit Design.

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2 weeks ago • Nature

Accurate DNA base editing guided by AlphaFold3 protein contact predictionsPrecise DNA base editing using AlphaFold3-based contact modelling.

1 week ago • bioRxiv : the preprint server for biology

Identifying essential genes in Streptococcus mutans and finding a working equivalent of the cell division regulator RocSDeciphering the Streptococcus mutans essentialome: multi-omic resolution of hypothetical genes and identification of a functional RocS equivalent.

Preprint

5 days ago • International immunopharmacology

Live CRISPR screening finds LTA4H may boost immunotherapy by affecting LTB4-driven neutrophil responseIn vivo CRISPR screening identifies LTA4H as a target for potentiating immunotherapy efficacy via the LTB4-neutrophil axis.

Article

2 weeks ago • Nature

CRISPR-Cas controls activity of built-in anti-virus defense systemsCRISPR-Cas regulates expression of embedded anti-phage defence systems.

2 weeks ago • Molecular cell

CRISPR-Cas12a2 kills cells by recognizing specific RNAProgrammable cell killer: CRISPR-Cas12a2 eliminates cells via RNA identity.

4 weeks ago • Nature

Safe cell transplantation and selection inside the body using targeted surface marker changesNon-genotoxic transplantation and in vivo selection through epitope editing.

2 weeks ago • Advanced genetics (Hoboken, N.J.)

Small Cas12 Tools for Editing Multiple Plant Systems That Handle Environmental StressCompact Cas12 Systems for Multiplex Engineering of Plant Abiotic-Stress Networks.

2 weeks ago • bioRxiv : the preprint server for biology

Design and Analysis of CRISPR Gene Editing Tests Focused on Specific Genome Areas Using FRACTELRegion-Level Design and Analysis of CRISPR Perturbation Screens with FRACTEL.

3 weeks ago • bioRxiv : the preprint server for biology

Key proteins control how heparan sulfate is modified and binds to other molecules, found using CRISPR activation screensCRISPR activation screens identify core protein-dependent regulation of heparan sulfate sulfation and ligand specificity.

1 month ago • The Plant journal : for cell and molecular biology

Efficient gene editing of plants without added genes using virus-based deliveryEfficient CRISPR-Cas9 delivery and transgene-free multiplex genome editing in plants using cymbidium mosaic virus-derived vectors.

4 days ago • bioRxiv : the preprint server for biology

CRISPR tests and humanized liver mice identify host factors for hepatitis B virusOrthogonal CRISPR screens and human liver chimeric mice identify hepatitis B virus host factors.

Preprint

2 days ago • Marine biotechnology (New York, N.Y.)

A Reliable Method to Deliver Gene Editing Tools and Instructions into Fish EmbryosA Reproducible Electroporation Strategy for CRISPR-Cas9 RNP and mRNA Delivery in Fish Embryos.

Article

2 weeks ago • bioRxiv : the preprint server for biology

Improved β-thalassemia treatment using protected blood stem cell transplant with toxin-free preparation and natural selection inside the bodyCD117 epitope-shielded hematopoietic stem cell transplantation with toxin-free conditioning and in vivo selection ameliorates a β-thalassemia model.

3 weeks ago • The Plant cell

Editing the MYB factor APL to change flowering timeThe MYB transcription factor APL is a rational target for base editing to engineer flowering time.

3 weeks ago • BMC methods

An Easy Fluorescent Method to Improve Gene Editing in Human Stem CellsA simple and versatile fluorescence-based method to enhance prime editing in human pluripotent stem cells.

3 weeks ago • microPublication biology

Using zebrafish with altered leiomodin 2b gene to model dilated heart diseaseNovel leiomodin 2b crispant zebrafish as a model for dilated cardiomyopathy.

3 weeks ago • bioRxiv : the preprint server for biology

Detailed CRISPR Study of the WAVE Complex Finds Drugs That Affect Movement of Brain Immune Cells Linked to Alzheimer’sDense CRISPR Mapping of the WAVE Complex Identifies Pharmacological Modulators of AD-Linked Myeloid Migration.

3 weeks ago • bioRxiv : the preprint server for biology

Blocking a key recycling process slows pancreatic cancer growth and makes it more sensitive to mTORC1-targeted treatmentVertical inhibition of the autophagy pathway impairs growth and enhances sensitivity to mTORC1 inhibition in pancreatic ductal adenocarcinoma.

4 weeks ago • Life sciences

Gene-edited heart cells modeling short QT syndrome type 3 show electrical differences and varied drug responsesPrime-edited isogenic hiPSC-derived cardiomyocyte model of short QT syndrome type 3 reveals electrophysiological phenotypes and differential drug responses.

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CRISPR Gene Editing Research Papers