Longevity & Aging Research Papers | Page 6 | OpenScience.ink

1 week ago • Renal failure

Mitochondrial vesicles as new messengers between the heart and kidneys in cardiorenal syndromeMitochondrial extracellular vesicles in cardiorenal syndrome: emerging mediators of mitochondrial signaling and inter-organ crosstalk.

📖 Top 30% JournalArticle

1 week ago • Nature immunology

AMBRA1 activates NLRP3 by lifting its self-blocking mechanismAMBRA1 allosterically activates NLRP3 by releasing its autoinhibition.

🥇 Top 1% JournalArticle

1 week ago • GeroScience

A type of HDL with high apolipoprotein(a) speeds up blood vessel aging and artery disease by causing blood vessel lining cells to ageApolipoprotein(a)-rich electronegative HDL accelerates vascular aging and atherosclerosis by inducing endothelial senescence.

🎖️ Top 10% JournalArticle

1 week ago • Cell metabolism

Blocking PD-L2 may reduce buildup of aging cells and related declineBlocking PD-L2 prevents senescent cell accumulation and age-related dysfunction.

🥇 Top 1% JournalArticle

1 week ago • Communications biology

How a harmful cell aging process and chronic inflammation may speed up aging and related diseasesThe vicious cycle of SASP and inflammaging promotes aging and age-related diseases.

🥉 Top 5% JournalArticle

1 week ago • GeroScience

Copper and iron support cell survival through different metabolic processesCopper and iron engage distinct metabolic programs for cellular survival.

🎖️ Top 10% JournalArticle

1 week ago • Developmental cell

Senescent cells may leave behind cellular wasteSenescent cells: Leaving cellular waste behind.

🥇 Top 1% JournalComment

1 week ago • Journal of the American Heart Association

Gut Bacteria and Aldosterone Influence Heart Stress Signals to Trigger Cell Cleanup and Energy Changes in a Sepsis-Like Heart Injury ModelGut Microbiota and Aldosterone Regulate Natriuretic Peptide B Expression to Drive Mitophagy and Metabolic Reprogramming in Sepsis-Like Model of Myocardial Injury.

🥉 Top 5% JournalArticle

1 week ago • The Journal of investigative dermatology

IgG Build-up with Aging May Increase Skin InflammationAging-related IgG accumulation promotes skin inflammation.

🎖️ Top 10% JournalArticle

1 week ago • Autophagy

Timing and location of Atg9 vesicle fusion during autophagosome formationSpatiotemporal control of Atg9 vesicle fusion in autophagosome formation.

🥈 Top 2% JournalArticle

1 week ago • iScience

Early high-fat diet changes adult metabolism in fruit fliesEarly life high-fat diet exposure modulates adult metabolic phenotypes in Drosophila.

🎖️ Top 10% JournalArticle

1 week ago • Science advances

Androgen receptor helps muscle stem cells stay active and maintain their supply for life-long repairAndrogen receptor imprints satellite cell stemness and preserves their reservoir for lifelong regeneration and optimal repair.

🥈 Top 2% JournalArticle

1 week ago • Cell

Calorie restriction changes overall mutation levels in mouse body cellsCaloric restriction modulates genome-wide somatic mutation in mice.

🏆 Top 0.1% JournalArticle

1 week ago • Journal of the American Heart Association

Faster Aging in Fontan Patients Linked to Right-Sided Heart Pumps and Poor Blood FlowAccelerated Aging Fontan Phenotype Is Associated With Systemic Right Ventricles and Adverse Hemodynamics.

🥉 Top 5% JournalArticle

1 week ago • Molecular neurobiology

Muscarinic M1 and Histamine H1 Receptor Signals Working Together Through the PI3K/Akt/mTOR Pathway in Brain Inflammation and Myelin Repair in Multiple SclerosisGPCR-Driven Muscarinic M1 and Histamine H1 Receptor Signaling Converging on the PI3K/Akt/mTOR Pathway: Functional Integration in Neuroinflammation and Myelin Repair in Multiple Sclerosis.

🎖️ Top 10% JournalArticle

1 week ago • Ageing research reviews

Cellular Aging as a Breakdown in Hormone SignalingCellular senescence as endocrine information failure in aging.

🥈 Top 2% JournalArticle

1 week ago • International journal of biological macromolecules

A plant sugar from Anemarrhena asphodeloides may extend lifespan in worms through a key longevity proteinA homogalacturonan polysaccharide from Anemarrhena asphodeloides promotes longevity in Caenorhabditis elegans with involvement of DAF-16/FOXO.

📖 Top 20% JournalArticle

1 week ago • Reproduction & fertility

Mouse egg cell types show different blastocyst responses to resveratrol and vitamin B12Mouse oocyte phenotypes differ in blastocyst response to resveratrol and vitamin B12.

📖 Top 20% JournalArticle

1 week ago • Pharmacological research

Possible Anti-Aging Benefits of Diabetes Medicines Linking Type 2 Diabetes and Faster AgingSenotherapeutic Potential of Anti-Diabetic Medications: Bridging Type 2 Diabetes and Accelerated Aging.

🥉 Top 5% JournalArticle

1 week ago • Cell chemical biology

Studying key histone-modifying enzymes using peptide toolsInvestigation of the classical histone deacetylases and sirtuins using peptide technologies.

🥉 Top 5% JournalArticle

1 week ago • GeroScience

LAPTM5 is linked to retinal cell aging and scarring through a mitochondrial cleanup process and immune activation in an aging modelLAPTM5 correlates with RPE senescence and subretinal fibrosis through the LAPTM5-WWP2-OPTN mitophagy cascade and cGAS/STING activation in a D-galactose-induced aging model.

🎖️ Top 10% JournalArticle

1 week ago • American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

NLRP3-driven liver immune cell death worsens injury after transplant from older donors through a CD38-NAD+-Sirt1 pathway affecting ERRα functionNLRP3 Mediated Kupffer Cell Pyroptosis Aggravated Ischemia-reperfusion Injury After Aging Donor Liver Transplantation Through CD38-NAD+-Sirt1 Dependent Acetylation of ERRα.

🥉 Top 5% JournalArticle

1 week ago • GeroScience

Infection patterns over time linked to faster biological aging in adultsLongitudinal infection trajectories and biological aging acceleration in adults: a prospective cohort study.

🎖️ Top 10% JournalArticle

1 week ago • Pediatric research

How Early-Life Factors May Cause Lasting Lung Changes in Bronchopulmonary Dysplasia Through Epigenetic ProgrammingEpigenetic programming in bronchopulmonary dysplasia: a framework linking early-life exposures to persistent lung disease-a narrative review.

📖 Top 20% JournalArticle

1 week ago • Materials today. Bio

Nanoparticles carrying Panax notoginseng polysaccharides reduce Alzheimer's symptoms by changing immune cell metabolism through energy and oxygen sensing pathwaysMicroglia-targeted Panax notoginseng polysaccharide nanoparticles alleviate Alzheimer's disease via AMPK-mTOR/HIF-1α-mediated immunometabolic reprogramming.

🥉 Top 5% JournalArticle

1 week ago • Talanta

A fluorescent probe that shows mitochondrial nitric oxide and pH changes during cell self-cleaningA mitochondria-targeted ratiometric fluorescent probe for visualizing NO generation coupled with mitochondrial pH variations during autophagy.

📖 Top 20% JournalArticle

2 weeks ago • Ageing research reviews

Contacts Between Cell Energy and Protein Factories May Influence Aging of Brain Immune Cells in Alzheimer's DiseaseMitochondria-endoplasmic reticulum contact sites (MERCS/MAM): Multi-layered upstream regulators of microglial senescence in Alzheimer's disease.

🥈 Top 2% JournalArticle

2 weeks ago • Ageing research reviews

Using Biomaterials to Help Older Bones Heal and Stop the Cycle of AgingBreaking the Self-Reinforcing Cycle of Aging: Biomaterial Strategies for Aged Bone Regeneration.

🥈 Top 2% JournalArticle

2 weeks ago • Biomaterials

Vitamin E-NAD+ nanoparticle treatment for osteoarthritis by reducing inflammation and oxidative stressBioactive vitamin E-NAD+ conjugate nanoparticles for osteoarthritis management via simultaneous suppression of inflammation and oxidative stress.

🥉 Top 5% JournalArticle

2 weeks ago • Annals of hepatology

Role of CD38 in Liver Disease: How It Works, Links to Illness, and Treatment PossibilitiesCD38 in hepatic pathobiology: mechanisms, disease association and therapeutic implications.

📖 Top 20% JournalArticle

← prevpage 6 of 16next →