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1 week ago • PeerJ

Understanding biological aging using metabolism markersDecoding aging clocks from a metabolomic perspective.

📖 Top 30% JournalArticle

1 week ago • iScience

Chromatin pieces with TRF2 in the cell fluid trigger cGAS-STAT1 inflammation during cell agingTRF2 enriched cytoplasmic chromatin drives cGAS-STAT1-mediated inflammation in senescence.

🎖️ Top 10% JournalArticle

1 week ago • Signal transduction and targeted therapy

How cells keep mitochondria healthy and possible treatments for related diseasesMitochondrial quality control in health and disease: mechanisms and therapeutic targets.

🥇 Top 1% JournalArticle

1 week ago • Ageing research reviews

Is amyloid beta peptide a cause of age-related chronic inflammation?Is amyloid beta peptide a driver of inflammaging?

🥈 Top 2% JournalArticle

1 week ago • The Journal of biological chemistry

Sugar-Modified CD147 Triggers Cell Cleanup to Reduce Fibroblast Activation and TransformationAutophagy Induced by Glycosylated CD147 Attenuates Fibroblast Activation and Myofibroblast Differentiation.

🎖️ Top 10% JournalArticle

1 week ago • European heart journal

Activation of the AMPK/USP10 cycle increases ACE2 and its possible link to lung high blood pressureAMPK/USP10 loop activation of ACE2: implications for pulmonary hypertension.

🥇 Top 1% JournalArticle

1 week ago • Journal of assisted reproduction and genetics

MAFF may cause aging in womb lining cells by reducing antioxidant defenses in repeated pregnancy lossMAFF promotes decidual stromal cell senescence by suppressing NRF2-mediated antioxidant responses in recurrent pregnancy loss.

📖 Top 20% JournalArticle

1 week ago • Journal of studies on alcohol and drugs

High-Intensity Interval Training May Reduce Heart Cell Stress and Repair Problems in Healthy Rats After Taking Methylphenidate and AlcoholHigh-Intensity Interval Training Ameliorates Oxidative Stress and Mitophagy in Heart Tissue of Healthy Rats Following the Combination Use of Methylphenidate and Ethanol.

📖 Top 30% JournalArticle

1 week ago • Biochimica et biophysica acta. Gene regulatory mechanisms

NMN may reduce hair loss damage by activating a protective protein and boosting glutamine useNMN alleviates oxidative stress damage in alopecia areata by activating SIRT7 and promoting glutamine metabolism.

📖 Top 20% JournalArticle

1 week ago • Redox biology

The complex role of energy-producing cell molecules in controlling aging and its signsThe nuanced role of mitochondrial ROS in modulating aging and aging hallmarks.

🥈 Top 2% JournalArticle

1 week ago • Aging and disease

Using Worms and Mice to Find and Rank Treatments for Age-Related Muscle LossA C. elegans-to-Mouse Discovery Framework for Prioritizing Sarcopenia Interventions.

🥉 Top 5% JournalArticle

1 week ago • Autophagy

How cell cleanup and nitric oxide change immune metabolism: a possible new approach for asthma treatmentAutophagy-nitric oxide reprogramming of immune metabolism: a potential avenue for asthma therapeutic advancement.

🥈 Top 2% JournalArticle

1 week ago • Cell cycle (Georgetown, Tex.)

Gene and data analysis finds fat metabolism and protein tagging patterns and suggests ATG5, ASB4, LDLR, and CD36 as possible markers for insulin resistanceIntegrated multi-level transcriptomic and bioinformatics analysis identifies lipid metabolism-ubiquitination signatures and reveals ATG5, ASB4, LDLR, and CD36 as Candidate biomarkers in insulin resistance.

📖 Top 20% Journal

1 week ago • Neurotoxicology

How Perfluorooctanoic Acid May Cause Brain Cell Loss and Thinking Problems by Disrupting Cell Energy Management and Blood-Brain Barrier FunctionMechanisms Underlying Perfluorooctanoic Acid-Induced Neuronal Loss and Cognitive Deficits: Disruption of Mitochondrial Dynamics, Impaired Mitophagy, and Blood-Brain Barrier Dysfunction.

📖 Top 20% Journal

1 week ago • Pediatric research

Changing role of energy-making cell problems and their cleanup in severe intestinal tissue damageEvolving role of mitochondrial dysfunction and mitophagy in necrotizing enterocolitis.

📖 Top 20% Journal

1 week ago • Advanced materials (Deerfield Beach, Fla.)

Biomimetic Skin Inspired by Turritopsis nutricula May Help Heal Aged Wounds by Changing Mitochondrial Metabolism Through DAZAP1 Phase SeparationTurritopsis nutricula-Inspired Engineered Biomimetic Skin Promoting Aged Wound Repair via DAZAP1 Phase Separation-Related Mitochondrial Metabolism Reprogramming.

🥇 Top 1% Journal

1 week ago • Phytomedicine : international journal of phytotherapy and phytopharmacology

How complex sugars change cell energy systems and relate to chemotherapy resistance in digestive system cancersPolysaccharides-mediated mitochondrial remodeling: role in chemotherapy resistance of gastrointestinal tumors.

🎖️ Top 10% Journal

1 week ago • Ecotoxicology and environmental safety

Cadmium may cause kidney damage through a daily rhythm-related inflammation and aging process that can be reduced by goji berry extract and melatoninCadmium induces renal injury via a BMAL1-dependent inflammatory and senescence cascade: Attenuation by Lycium barbarum polysaccharide and melatonin.

🎖️ Top 10% Journal

1 week ago • Journal of advanced research

Using a special chemical method to attach tightly packed DNA to the cell's outer nucleus layer reverses aging and joint diseaseBioorthogonal epigenetic anchoring of heterochromatin to the nuclear lamina reverses senescence and osteoarthritis.

🥉 Top 5% Journal

1 week ago • Ageing research reviews

Targeting a Key Immune Trigger in Alzheimer's Disease: Understanding How It Works and New Treatment ApproachesTargeting the NLRP3 inflammasome in Alzheimer's disease: Mechanistic insights and therapeutic advances.

🥈 Top 2% Journal

1 week ago • Journal of Huntington's disease

Early treatment with 4',5,7-trihydroxyisoflavone may prevent severe Huntington's disease symptoms in a mouse modelPrevention of appearance of severe Huntington's disease symptoms in the R6/1 mouse model by early administration of 4',5,7-trihydroxyisoflavone.

🎖️ Top 10% Journal

1 week ago • Autoimmunity reviews

Aging of the immune system in lupus: causes, health effects, and treatment possibilitiesImmunosenescence in systemic lupus erythematosus: Mechanisms, clinical consequences, and therapeutic implications.

🥉 Top 5% Journal

1 week ago • Neurotoxicology

Aluminum and Alzheimer's Disease: A Review of Current Evidence and DebatesAluminum and Alzheimer's disease in the 21st century: An umbrella review of evidence and controversies.

📖 Top 20% Journal

1 week ago • American journal of physiology. Lung cellular and molecular physiology

How FCCP Triggers Mitochondrial Cleanup in Human Airway Muscle CellsMolecular Mechanisms Underlying FCCP-Induced Mitophagyin Human Airway Smooth Muscle Cells.

📖 Top 20% Journal

1 week ago • JACC. Basic to translational science

Problems in Mitochondrial Cleanup and Movement in AtherosclerosisDisrupted Mitochondrial Quality Control in Atherosclerotic Disease: Mitophagy and Dynamics in Focus.

🥉 Top 5% Journal

1 week ago • Journal of community health

Frequent Nighttime Urination Is Linked to Biological Age, Not Actual AgeNocturia is Associated with Biological Age not Chronological Age.

📖 Top 20% Journal

1 week ago • Science advances

Different roles of COPI proteins reduced during cell agingDistinct roles of COPI proteins attenuated in cell senescence.

🥈 Top 2% Journal

1 week ago • Carbohydrate polymers

Recent progress and potential treatments using cyclodextrin to deliver resveratrolCyclodextrin-mediated delivery of resveratrol: Recent advances, therapeutic potential, and future perspectives.

🥉 Top 5% Journal

1 week ago • Journal of Alzheimer's disease : JAD

Chemical agents that change brain connections: New possibilities for Alzheimer's treatmentBiochemical modulators of synaptic plasticity: New horizons in Alzheimer's disease treatment.

📖 Top 20% Journal

2 weeks ago • STAR protocols

Method for identifying aging cells using single-cell and single-nucleus RNA sequencing dataProtocol for classifying cellular senescence from single-cell and single-nucleus RNA sequencing data.

📖 Top 20% Journal

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Longevity & Aging Research Papers