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2 weeks ago • Diabetes

Faster Biological Aging in Diabetic Kidney Disease Compared Using 10 Epigenetic Clocks in People with Type 1 DiabetesAccelerated Epigenetic Ageing in Diabetic Kidney Disease: A Comparison of 10 Epigenetic Clock Measures in Individuals With Type 1 Diabetes.

🥉 Top 5% JournalArticle

2 weeks ago • Nature neuroscience

Disrupted cholesterol movement by ABCA1 may lead to nerve cell damage in Parkinson's diseaseDysregulated cholesterol trafficking through ABCA1 drives neurodegeneration in Parkinson's disease.

🥇 Top 1% JournalArticle

2 weeks ago • Bioactive materials

Controlled RNA delivery using charged gelatin nanoparticles may protect against spinal disc degeneration by targeting mTORC1Cationized gelatin nanosphere-mediated release-controlled RNA interference targeting mTORC1 protects against intervertebral disc degeneration.

🥈 Top 2% JournalArticle

2 weeks ago • Plastic and reconstructive surgery

Partial Cell Reprogramming as a New Approach in Plastic SurgeryA New Frontier: Partial Cellular Reprogramming in Plastic Surgery.

📖 Top 20% JournalArticle

2 weeks ago • Genes & diseases

Glis1 supports cell metabolism by increasing H3K18 lactylation to reduce nerve cell aging after spinal cord injuryGlis1 regulates metabolic programming by promoting H3K18 lactylation to alleviate neuronal senescence following spinal cord injury.

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2 weeks ago • Autophagy

How PTEN-L controls PRKN to link reduced removal of damaged mitochondria with lower inflammatory cell deathPRKN dephosphorylation by PTEN-L couples mitophagy inhibition to GSDME pyroptosis suppression.

🥈 Top 2% JournalArticle

2 weeks ago • Experimental neurology

How exercise training may improve energy control in the memory area of the brain in Alzheimer's diseaseEffectiveness of exercise training on hippocampal mitochondrial regulation in Alzheimer's disease: A mechanistic systematic review.

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2 weeks ago • Autoimmunity reviews

Long-lasting antibody-producing cells in rheumatic and certain autoimmune diseases: biology, evidence, and treatment optionsLong-lived plasma cells in rheumatic and selected antibody-mediated autoimmune diseases: biology, evidence, and therapeutic opportunities.

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2 weeks ago • RSC advances

Chemical comparison of tea and coffee extracts finds a green tea component that may block two digestive enzymesComparative biochemical analysis of tea (Camellia sinensis) and coffee (Coffea arabica) extracts identifies the ethyl acetate fraction of green tea as a potential dual digestive enzyme inhibitor: an in vitro and in silico study.

📖 Top 30% JournalArticle

2 weeks ago • Food & function

Gene activity differences show unique anti-aging roles and teamwork among three probiotics in a worm modelComparative transcriptomics reveals distinct anti-aging specificities and functional complementarity among three probiotic strains in Caenorhabditis elegans.

📖 Top 20% JournalArticle

2 weeks ago • The Lancet. Digital health

Using AI to Identify Health Conditions from Face Photos: Developing and Testing a New ModelFoundation artificial intelligence models for health recognition by use of face photographs (FAHR-Face): a model development and validation study.

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2 weeks ago • Signal transduction and targeted therapy

Mitochondria cleanup helps communication between cell parts in health and diseaseMitophagy coordinates organelle crosstalk in health and diseases.

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2 weeks ago • Inflammopharmacology

Resveratrol supplements and their link to inflammation and oxidative stress in metabolic disorders: a review and dose analysis of clinical trialsEffects of resveratrol supplementation on inflammatory and oxidative stress biomarkers in metabolic disorders: a systematic review and dose-response meta‑analysis of randomized controlled trials.

📖 Top 20% JournalArticle

2 weeks ago • BMC complementary medicine and therapies

Resveratrol's effects on memory-related brain areas in a chemical model of epilepsyThe effect of resveratrol on the hippocampus in the pentylenetetrazol (PTZ) - dependent kindling model of epilepsy.

📖 Top 30% JournalArticle

2 weeks ago • Veterinary and animal science

Clodronate and trehalose together unexpectedly reduce growth of dog mammary tumor cellsClodronate and trehalose exhibit a paradoxical antagonistic interaction that suppresses proliferation of canine mammary tumour cells.

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2 weeks ago • Molecular neurobiology

Withaferin A's potential protective effects in Huntington's disease: current findings and future outlookNeuroprotective Role of Withaferin A in Huntington's Disease: Current Evidence and Future Perspectives.

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2 weeks ago • International journal of biological macromolecules

Nicotinamide mononucleotide helps improve polycystic ovary syndrome by boosting energy use through activating a protein that changes lactate dehydrogenaseNicotinamide mononucleotide supplementation improves polycystic ovary syndrome by activating silent regulatory protein 2 mediated lactate dehydrogenase A lysine 119 deacetylation to enhance glycolytic activity.

📖 Top 20% JournalArticle

2 weeks ago • The Journal of nutritional biochemistry

Paeoniflorin May Protect Against Acute Kidney Injury by Boosting Mitochondrial Cleanup Through PRDX5 Inhibiting RACK1Paeoniflorin Promotes Mitophagy Against Acute Kidney Injury via PRDX5-Dependent Inhibition of RACK1.

📖 Top 20% JournalArticle

2 weeks ago • Advanced healthcare materials

Using Nano-Enhanced 3D Environments to Control Cell Vesicles for Reducing Cell Death and Supporting Muscle Repair in DiabetesMultimodal Programming of Extracellular Vesicles via Nano-Primed SECCS-Based 3D Microenvironments for Coordinated Ferroptosis Suppression and Myogenic Regeneration in Diabetes.

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2 weeks ago • RSC chemical biology

Using NAD+-like molecules to understand how PARP enzymes add ADP-ribose in cellsNAD+ analogues for decoding the biological chemistry of PARP-mediated ADP-ribosylation.

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2 weeks ago • Aesthetic surgery journal

Possible roles of NAD+ in cosmetic plastic surgery: A review of current evidenceDoes NAD+ Have a Role in Aesthetic Plastic Surgery? An Evidence-Based Review.

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2 weeks ago • International journal of hygiene and environmental health

Day, night, and combined heatwaves linked to faster biological aging in China over timeDaytime, nighttime, and day-night compound heatwaves and accelerated biological ageing: national cross-sectional and longitudinal evidence in China.

🎖️ Top 10% JournalArticle

2 weeks ago • Trends in parasitology

Link between behavior, metabolism, and cell recycling in ticks and mosquitoesBehavior-metabolism-autophagy axis in ticks and mosquitoes.

🎖️ Top 10% JournalArticle

2 weeks ago • Cytokine & growth factor reviews

Aging Immune System in Colorectal Cancer: How Gut Bacteria, Chronic Inflammation, and Cell Metabolism InteractImmunosenescence in colorectal cancer: Interplay of microbiota, inflammaging, and metabolic reprogramming.

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2 weeks ago • Cell metabolism

A flexible approach to targeting cell energy metabolism in cancerA context-dependent framework for targeting NAD metabolism in cancer.

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2 weeks ago • Cancer letters

Using CRISPR to identify key factors, stress protection, and treatment weaknesses in alternative telomere lengtheningCRISPR-based interrogation of alternative lengthening of telomeres: mapping dependencies, stress-buffering pathways, and therapeutic vulnerabilities.

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2 weeks ago • Bioactive materials

Targeting aging cells linked to NOX4 with iron-removing treatment to slow spine disc degenerationReprogramming NOX4-associated ferro-aging with an iron-chelating senescent-cell-targeted therapy for intervertebral disc degeneration.

🥈 Top 2% JournalArticle

2 weeks ago • Hepatology communications

Liver cell aging linked to metabolic fat-related liver diseaseHepatocyte senescence in metabolic dysfunction-associated steatotic liver disease (MASLD).

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2 weeks ago • European journal of pharmacology

Rapamycin's possible role in neural tube defects based on computer analysis and lab experimentsThe role of rapamycin in neural tube defects: insights from bioinformatics analysis and experimental validation.

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2 weeks ago • Pharmacological research

How Cell Stress and Energy Problems Interact in Inflammatory Bowel Disease and Possible TreatmentsInterplay Between Endoplasmic Reticulum Stress and Mitochondrial Dysfunction in Inflammatory Bowel Disease: From Molecular Mechanisms to Therapeutic Opportunities.

🥉 Top 5% JournalArticle

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