OpenScience.ink

2 weeks ago • Cell metabolism

Understanding Actual Age versus Body’s Biological Age in Age Reversal ClaimsAging vs. biological age: Conceptual considerations for age reversal claims.

🥇 Top 1% JournalArticle

2 weeks ago • Ageing research reviews

New Approaches to Treat Aging by Targeting Cell Aging MarkersTargeting senescence-associated biomarkers: Emerging strategies for anti-ageing therapy.

🥈 Top 2% JournalArticle

2 weeks ago • Journal of environmental sciences (China)

Brain cell damage in rats from 2,5-hexanedione linked to a process where damaged mitochondria trigger iron-related cell deathMitophagy-mediated ferroptosis involved in 2,5-hexanedione-induced neurotoxicity in rats.

🎖️ Top 10% JournalArticle

2 weeks ago • Journal of environmental sciences (China)

Common levels of DCOIT reduce lifespan and health in Caenorhabditis elegansEnvironmentally relevant concentrations of DCOIT impaired lifespan and healthspan in Caenorhabditis elegans.

🎖️ Top 10% JournalArticle

2 weeks ago • Cell reports

MGRN1 helps protect temporarily damaged energy centers in cells for antioxidant repairMGRN1 preserves transiently damaged mitochondria for antioxidant-mediated repair.

🥈 Top 2% JournalArticle

2 weeks ago • Food research international (Ottawa, Ont.)

Resveratrol improves high-fat diet caused ovarian damage by changing gut bacteria and restoring ovarian energy use and gene activityResveratrol ameliorates High-Fat Diet induced ovarian damage by reshaping gut microbiota and reversing aberrant ovarian energy metabolism and gene expression.

🎖️ Top 10% JournalArticle

2 weeks ago • Biogerontology

📖 Top 20% JournalArticle

2 weeks ago • Journal of sport and health science

Short-term passive heat exposure changes cell recycling and stress responses in older active adultsShort-term passive heat acclimation modulates autophagy and cellular stress responses in older active adults.

🥉 Top 5% JournalArticle

2 weeks ago • International journal of oral science

PFKM triggers donut-shaped changes in energy structures to support bone formationPFKM acts as a metabolic switch initiating donut-shaped mitochondrial remodeling to promote osteogenesis.

🥉 Top 5% JournalArticle

2 weeks ago • Journal of Alzheimer's disease : JAD

Terpenoids may reduce Alzheimer's symptoms by boosting cell antioxidants and clearing damaged mitochondria through the Keap1/Nrf2/ARE pathwayResearch progress on terpenoids alleviating Alzheimer's disease through the Keap1/Nrf2/ARE pathway by exerting antioxidant effects and promoting mitophagy.

📖 Top 20% JournalArticle

2 weeks ago • Autophagy

Cell self-cleaning of RAB8A may increase iron uptake problems that lead to ferroptosisAutophagic degradation of RAB8A promotes ferroptosis through dysregulation of TFRC-mediated iron uptake.

🥈 Top 2% JournalArticle

2 weeks ago • International journal of pharmaceutics: X

Nanovesicles carrying SRT1720 may improve diabetic brain stroke by boosting cell cleanup through SIRT1 and PARKIN in ratsSRT1720-loaded exosome-mimetic nanovesicles promote mitophagy via SIRT1/PARKIN activation to ameliorate diabetic cerebral infarction in a preclinical rat model.

📖 Top 20% JournalArticle

2 weeks ago • Autophagy

Thyroid hormone helps reshape fat storage and fat recycling in early embryos through KAT2B/PCAF-controlled gene regulationThyroid hormone promotes lipid droplet remodeling and lipophagy through KAT2B/PCAF-dependent histone acetylation in preimplantation embryos.

🥈 Top 2% JournalArticle

2 weeks ago • iScience

How the shape and role of actin affect its condition and the aging processForm and function of actin impacts actin health and aging.

🎖️ Top 10% JournalArticle

3 weeks ago • Ageing research reviews

Non-Communicable Diseases May Be an Unavoidable Result of Living Longer Than Our Evolution Prepared Us ForLiving Beyond Our Evolutionary Warranty: Why Non-Communicable Diseases May Be The Inevitable Costs of an Extended Lifespan.

🥈 Top 2% JournalArticle

3 weeks ago • Journal of molecular and cellular cardiology plus

Problems in cell structure networks in primary heart muscle disease: Understanding causes and treatmentsOrganelle network dysfunction in primary cardiomyopathy: An integrated perspective on pathogenesis and therapeutics.

📖 Top 30% JournalArticle

3 weeks ago • Environment international

A new two-part AhR process linked to heart aging caused by 6PPDQA novel dual-pathway AhR mechanism underpins cardiac senescence induced by 6PPDQ.

🥉 Top 5% JournalArticle

3 weeks ago • Pharmacological research

Eriodictyol controls a key enzyme to activate mitochondrial cleaning that reduces inflammation for treating bone lossEriodictyol regulates LDHB to trigger mitophagy-mediated NLRP3 inflammasome inactivation as a therapeutic strategy for bone loss.

🥉 Top 5% JournalArticle

3 weeks ago • Pharmacological research

Understanding How Bile Acids and Energy Centers in Cells Work Together: Possible Links to Disease and Treatment OptionsDecoding the bile acid-mitochondria axis: Implications for disease management and therapeutic opportunities.

🥉 Top 5% JournalArticle

3 weeks ago • Bioactive materials

Using mRNA nanoparticles to fix cholesterol balance and help heal age-related bone damageA dual-targeting mRNA lipid nanoparticle restores ABCA1-dependent cholesterol homeostasis to promote repair of age-related bone defects.

🥈 Top 2% JournalArticle

3 weeks ago • Angewandte Chemie (International ed. in English)

Detecting Aging-Related Enzyme Activity at the Single-Molecule LevelIdentification of Senescence-Associated β-Galactosidase With Single-Molecule Resolution.

🥇 Top 1% JournalArticle

3 weeks ago • Talanta

Using DNA nanodevices to gather lysosomes near the cell nucleus to control their functionDNA nanodevice-mediated perinuclear accumulation of lysosomes for functional regulation.

📖 Top 20% JournalArticle

3 weeks ago • Autophagy

PINK1’s expanded role in monitoring and controlling mitochondriaA New agent in the matrix: PINK1's expanded role in mitochondrial surveillance and Regulation.

🥈 Top 2% JournalArticle

3 weeks ago • Developmental cell

Senescent cells stay alive by breaking apart while attached, which helps spread cell fragmentsSenescent cells maintain viability through adhesion-dependent fragmentation that promotes debris deposition.

🥇 Top 1% JournalArticle

3 weeks ago • Journal of ethnopharmacology

Forsythoside A may ease high blood pressure kidney damage by boosting cell cleanup and blocking cell death through the ASCL1-CCNB1/mTOR pathwayForsythoside A alleviates hypertensive nephropathy by promoting mitophagy and inhibiting ferroptosis via ASCL1-CCNB1/mTOR pathway.

📖 Top 20% JournalArticle

3 weeks ago • Science advances

Neuron-produced SPP1 signals microglia to reduce brain cell damageNeuron-derived SPP1 instructs microglia to limit degeneration.

🥈 Top 2% JournalArticle

3 weeks ago • Science advances

GGA1 controls enzyme sorting and cell cleanup by changing lipid balance in the cell’s sorting centerSorting of lysosomal enzyme and autophagy are regulated by the GGA1-induced TGN lipid scrambling.

🥈 Top 2% JournalArticle

3 weeks ago • International journal of biological macromolecules

Polysaccharides that may improve organelle network problems in Alzheimer's diseasePolysaccharides targeting organelle network dysfunction in Alzheimer's disease: A review.

📖 Top 20% JournalArticle

3 weeks ago • Hormone research in paediatrics

Measuring Biological Age in Children: Comparing Methods and Medical UsefulnessEstimating the Biological Age in Children: Multiple Methods and Their Clinical Utility.

📖 Top 20% JournalArticle

3 weeks ago • Health psychology : official journal of the Division of Health Psychology, American Psychological Association

Social Isolation and Loneliness Linked to Faster Biological AgingSocial isolation, loneliness, and biological aging acceleration.

📖 Top 20% JournalArticle

← prevpage 8 of 16next →

Longevity & Aging Research Papers