OpenScience.ink

2 weeks ago • Ageing research reviews

Aging of brain blood vessel support cells linked to blood-brain barrier problems in Alzheimer's disease: causes, effects, and treatment possibilitiesNeurovascular unit senescence as a driver of blood-brain barrier dysfunction in Alzheimer's disease：Mechanisms, consequences, and therapeutic implications.

🥈 Top 2% Journal

2 weeks ago • Cell reports

TTYH3 controls chloride flow in lysosomes and affects their fusion, cell recycling, and agingTTYH3 regulates a lysosomal chloride conductance and controls lysosomal fusion, autophagy and senescence.

🥈 Top 2% Journal

2 weeks ago • Translational stroke research

PIP4K2A may reduce brain damage after stroke by lowering harmful protein buildup and adjusting cell survival signalsPIP4K2A Attenuates Cerebral Ischemia/Reperfusion Injury by Reducing the TRIB3-p62 Complex Burden and Modulating AKT/mTOR Signaling.

🎖️ Top 10% Journal

2 weeks ago • Ecotoxicology and environmental safety

Spermidine reduces egg cell damage from chemical exposure by restoring normal cell cleanup processes in miceSpermidine alleviates 2,2-dichloroacetamide/ 2,2-dibromoacetamide-exposed mouse oocyte toxicity by restoring autophagic homeostasis.

🎖️ Top 10% Journal

2 weeks ago • Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance

Faster Heart Ageing in Heart Disease: Findings from Heart Imaging and Electrical TestsAdvancing Heart Ageing in Ischemic Heart Disease: Insights from CMR and ECG Analysis.

🎖️ Top 10% Journal

2 weeks ago • Molecular neurobiology

Sirtuin Signaling in Parkinson's Disease and Brain Cell Loss: Molecular Understanding and Possible TreatmentsTargeting Sirtuin Signaling in Parkinson's Disease and Neurodegeneration: Molecular Insights and Translational Potential.

🎖️ Top 10% Journal

2 weeks ago • Archives of medical research

Physical Activity Linked to Faster Aging Measured by Body-Based Age in Older Mexican AdultsAssociation between Physical Activity and Accelerated Aging Using S-Anthropoage: A Secondary Analysis of the Mexican Health and Aging Study.

📖 Top 20% Journal

2 weeks ago • Ageing research reviews

How Palmitoylation Relates to Heart and Blood Vessel Aging and Disease, and Possible TreatmentsPalmitoylation in cardiovascular aging and disease: Mechanistic insights and therapeutic opportunities.

🥈 Top 2% Journal

2 weeks ago • Environmental geochemistry and health

How Microplastics Affect the Gut Microbiome and Ageing: Causes and Possible TreatmentsMicroplastics, the gut microbiome and ageing: mechanisms and intervention strategies.

📖 Top 20% Journal

2 weeks ago • Clinical epigenetics

Faster biological aging linked to slow heart rhythms: clinical and genetic evidenceBiological age acceleration and bradyarrhythmia: evidence from clinical and epigenetic perspectives.

🎖️ Top 10% Journal

2 weeks ago • Molecular metabolism

SAMM50 gene variant linked to energy problems in cells and worsening fatty liver disease related to metabolismSAMM50 rs3761472 causes mitochondrial dysfunction and progression of metabolic dysfunction-associated steatotic liver disease.

🥉 Top 5% Journal

2 weeks ago • Neurotoxicology

Manganese buildup may trigger cell aging, with the natural drug quercetin helping to reverse itManganese overload as a previously underappreciated trigger of cellular senescence: unraveling mechanisms and therapeutic rescue by the senolytic quercetin.

📖 Top 20% Journal

2 weeks ago • Inflammopharmacology

Resveratrol’s effects on cell activity and communication in protecting the brain from neurodegenerative diseasesResveratrol and neuroprotection: modulation of cellular dynamics and signaling networks in neurodegenerative diseases.

📖 Top 20% Journal

2 weeks ago • BMJ open

Safety and effectiveness of metformin for treating pain: review planSafety and efficacy of metformin for the treatment of pain: protocol for a systematic review.

📖 Top 20% Journal

2 weeks ago • Journal of pharmaceutical sciences

Melanin-coated nanoparticles targeting immune cells for combined delivery of rapamycin to treat atherosclerosisNeutrophil membrane-coated melanin nanoplatform: Targeted delivery of rapamycin and synergistic treatment of atherosclerosis.

📖 Top 30% Journal

2 weeks ago • RSC advances

Breakdown of nitrogen and boron-doped carbon nano-onions by cells and their role in triggering cell cleanup in immune cellsBiological degradation of B/N-doped carbon nano-onions and the autophagy induction in macrophages.

📖 Top 30% Journal

2 weeks ago • Cell death and differentiation

Schizophrenia and bipolar risk gene AKAP11 helps maintain thinking skills by controlling cell cleanup processesSchizophrenia and bipolar disorder risk gene AKAP11 sustains cognitive function by regulating TFEB-mediated autophagy.

🥇 Top 1% Journal

2 weeks ago • International journal of pharmaceutics

Stem cell membrane-coated nanoparticles may reduce heart scarring by restoring energy balance in heart cellsA biomimetic mesenchymal stem cell membrane-coated nanodelivery system attenuates cardiac fibrosis by restoring mitochondrial homeostasis.

📖 Top 20% Journal

2 weeks ago • Science bulletin

Inherited changes in a sugar-processing enzyme cause energy problems in cells linked to Parkinson's diseaseBiallelic hexose-6-phosphate dehydrogenase variants cause mitochondrial dysfunction underlying Parkinson's disease.

🥉 Top 5% Journal

2 weeks ago • Cyborg and bionic systems (Washington, D.C.)

Heatwaves may speed up aging by disrupting metabolismHeatwave Exposure Accelerates Biological Aging via Metabolic Dysregulation.

🥉 Top 5% Journal

2 weeks ago • The Journal of biological chemistry

O-GlcNAcylation acts as a signal between mitochondria and nucleus to control passive transport through the nuclear poreO-GlcNAcylation is a mitochondrial-nuclear signal that regulates passive transport through the nuclear pore complex.

🎖️ Top 10% Journal

2 weeks ago • Molecular neurobiology

Brain-Immune Control of NLRP3 Signaling in Parkinson’s DiseaseNeuroimmune Regulation of NLRP3 Signalling in Parkinson's Disease.

🎖️ Top 10% Journal

2 weeks ago • Molecular neurobiology

The role of necroptosis, a type of programmed cell death, in traumatic brain injuryIntegrated Necroptosis Within Programmed Cell Death in Traumatic Brain Injury.

🎖️ Top 10% Journal

2 weeks ago • Tissue barriers

Claudins as key regulators of scar tissue formation, cell recycling, and metabolismClaudins as signaling hubs of fibrosis, autophagy, and metabolism.

🎖️ Top 10% Journal

2 weeks ago • Cell death and differentiation

🥇 Top 1% Journal

2 weeks ago • ACS applied materials & interfaces

Targeted Delivery of Polyphenol Nanoparticles to Cell Membranes Using Receptor Binding for Alzheimer's TreatmentReceptor-Ligand-Mediated Anchoring of Polyphenol Quantum Dots to Membrane Fragments for Precision Delivery in Alzheimer's Disease Therapy.

🎖️ Top 10% Journal

3 weeks ago • Archives of biochemistry and biophysics

Inflammation and cell cleanup responses linked to METTL3/FOSL1 and m6A regulation in sepsis-related sudden kidney injuryMETTL3/FOSL1-associated inflammatory and autophagy-related responses involve m6A-related regulation in sepsis-induced acute kidney injury.

📖 Top 20% Journal

3 weeks ago • Acta pharmacologica Sinica

Lack of RNF10 in heart muscle cells weakens mitochondrial cleanup and leads to harmful heart enlargementRNF10 deficiency in cardiomyocytes impairs mitophagy and drives pathological hypertrophy.

🥉 Top 5% Journal

3 weeks ago • ACS applied materials & interfaces

Using a Tiny Enzyme Carrier with Resveratrol to Treat Osteoarthritis by Regulating Cell Signaling and Joint EnvironmentNanozyme Loaded with Resveratrol for Osteoarthritis Therapy via Wnt/β-Catenin Pathway and Microenvironment Regulation.

🎖️ Top 10% Journal

3 weeks ago • Nature communications

The SIRT5-SUCLG2 interaction slows ovarian aging through mitochondrial and gene regulationThe SIRT5-SUCLG2 desuccinylation axis delays ovarian aging via a mitochondrial-epigenetic regulatory mechanism.

🥈 Top 2% Journal

← prevpage 9 of 18next →

Longevity & Aging Research Papers