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3 weeks ago • Acta biomaterialia

Exact methods to remove aging cells to fight aging and related diseasesPrecise strategies for targeted elimination of senescent cells to combat aging and age-related diseases.

🥉 Top 5% Journal

3 weeks ago • Neuropharmacology

Enavogliflozin improves movement problems in Parkinson's disease mice by reducing cell damage and brain inflammation and activating protective cell pathwaysEnavogliflozin alleviates motor deficits in rotenone-induced Parkinson's disease mice via attenuation of oxidative stress and neuroinflammation as well as activation of the SIRT1/PINK1/Parkin pathway.

🎖️ Top 10% Journal

3 weeks ago • Nanomedicine : nanotechnology, biology, and medicine

Nanoceria particles protect mitochondria to reduce oxidative damage in light-related eye cell lossMitochondrial preservation underlies the antioxidant activity of nanoceria particles in light-induced retinal degeneration.

📖 Top 20% Journal

3 weeks ago • GeroScience

Faster biological aging linked to muscle aging signs in young and middle-aged adultsAssociation of biological age acceleration with muscle aging phenotype in young and middle-aged adults: a prospective cohort study.

🎖️ Top 10% Journal

3 weeks ago • Ageing research reviews

A Collection of Blood Markers for Aging in Humans: Understanding Their Role in Health and How Treatments May Change ThemA Compendium of Circulating Biomarkers of Senescence in Humans: Insights on Mechanistic Impact Across Health Domains and Modulation by Therapeutic Interventions.

🥈 Top 2% Journal

3 weeks ago • Free radical biology & medicine

Resveratrol Slows Aging in Young but Speeds Aging in Middle-Aged C. elegans through a Key Aging-Related PathwayResveratrol exerts anti-aging effects in young but pro-aging effects in middle-aged C. elegans via a gerosuppressive daf-16/dod-6/sod-3 axis.

🥉 Top 5% Journal

3 weeks ago • Translational research : the journal of laboratory and clinical medicine

How Physical Forces Affect Aging and Possible TreatmentsMechanical Signals in Aging: Mechanisms and Therapeutic Strategies.

🥉 Top 5% Journal

3 weeks ago • Cellular and molecular life sciences : CMLS

Chaperone-Mediated Cell Cleanup Controls Notch Signaling and Neural Stem Cell DevelopmentLAMP2A-dependent chaperone mediated autophagy regulates Notch signaling and controls neural stem cell differentiation.

🥉 Top 5% Journal

3 weeks ago • European journal of pharmacology

Glucosamine may help improve alcoholic liver disease and slow liver aging by activating energy-regulating pathwaysDrug repurposing of Glucosamine to ameliorate alcoholic liver disease and delay liver aging through activation of AMPK signaling pathway.

📖 Top 20% Journal

3 weeks ago • Journal of neuroinflammation

Microglial removal of damaged mitochondria as an immune and metabolic control point in Alzheimer's disease linking cell energy quality to brain inflammationMicroglial mitophagy as an immunometabolic checkpoint in alzheimer's disease: linking mitochondrial quality control to neuroinflammation.

🥉 Top 5% Journal

3 weeks ago • Nature communications

Citrulline increases age-related fat buildup linked to healthy agingCitrulline drives age-related lipid deposition for healthspan.

🥈 Top 2% Journal

3 weeks ago • Environmental toxicology and pharmacology

Antioxidant strength relates to different damage and aging rates in skin and lung cells exposed to workplace-level glyphosateAntioxidant efficiency is associated with differential susceptibility to oxidative damage and senescence progression in dermal and lung fibroblasts exposed to occupationally relevant glyphosate concentrations.

📖 Top 20% Journal

3 weeks ago • Nature structural & molecular biology

CST complex helps copy the second DNA strand during break-induced replicationCST complex promotes second-strand synthesis in break-induced replication.

🥇 Top 1% Journal

3 weeks ago • The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation

Understanding the mTOR Pathway in Lung Transplants: Could Biomarkers Guide Personalized Treatment?MAPPING THE MTOR PATHWAY IN LUNG TRANSPLANTATION: IS IT TIME FOR A BIOMARKER-DRIVEN PRECISION THERAPY?

🥉 Top 5% Journal

3 weeks ago • ACS applied materials & interfaces

A Nanoparticle System Carrying Donepezil for Alzheimer's Disease that Boosts Cell Cleanup and Reduces Brain InflammationA Multitarget Nanosystem Loaded with Donepezil for Alzheimer's Disease Treatment by Activating Mitophagy and Reshaping the Inflammatory Microenvironment.

🎖️ Top 10% Journal

3 weeks ago • Biogerontology

Silymarin reduces aging-related increases in brain inflammation, protein buildup, and oxidative stress linked to memory problems in miceSilymarin attenuates senescence-exacerbated amyloidogenesis, neuroinflammation, and oxidative stress in lipopolysaccharide-induced memory impairment in aging mice.

📖 Top 20% Journal

3 weeks ago • Journal of agricultural and food chemistry

Astragaloside IV May Reduce Long-Term Kidney Damage from Tacrolimus by Controlling a Key Cellular Stress PathwayAstragaloside IV Mitigates Tacrolimus-Induced Chronic Nephrotoxicity by Regulating the mTOR-TFEB-GADD45α Pathway.

📖 Top 20% Journal

3 weeks ago • Neurochemical research

Combined Elamipretide and NMN Treatment May Reduce Brain Damage After Stroke by Targeting TREM2 in MiceElamipretide (SS-31) and Nicotinamide Mononucleotide (NMN) Combination Therapy Targets TREM2 to Mitigate Post-ischemic Brain Injury in Mice.

📖 Top 20% Journal

3 weeks ago • Neurochemical research

A Mix of Four Natural Compounds May Reduce Memory Area Damage and Disease Signs in an Alzheimer's ModelA Combination of Artemisinin, N-acetylcysteine, Resveratrol, and Hesperidin Ameliorates Hippocampal Damage and Pathological Features in an Experimental Model of Alzheimer's Disease.

📖 Top 20% Journal

3 weeks ago • Journal of the science of food and agriculture

Using Caenorhabditis elegans as a model to study aging in food and nutrition researchPractical guideline for applying Caenorhabditis elegans as an aging model in food and nutritional research.

📖 Top 30% Journal

3 weeks ago • Inflammopharmacology

How Tau Protein Affects Cell Structures and Links to Brain DiseasesTau physiology and pathology: impacts on cellular structures and neurodegenerative diseases.

📖 Top 20% Journal

3 weeks ago • Journal of affective disorders

Trouble Sleeping and Faster Biological Aging Linked to Depressive Symptoms in Three GroupsThe associations of trouble sleeping, biological age acceleration with depressive symptoms: Evidence from three cohorts.

🥉 Top 5% Journal

3 weeks ago • Journal of Alzheimer's disease : JAD

Lack of damaged mitochondria removal and calcium imbalance linked to development and worsening of Alzheimer's diseaseMitophagy deficiency and calcium dyshomeostasis underlying the pathogenesis and progression of Alzheimer's disease.

📖 Top 20% Journal

3 weeks ago • Analytical chemistry

Liver-focused molecular probe to visualize aging donor livers with multiple imaging methodsLiver-Targeted Triple-Modal Molecular Probe for Visualization of Aging Marginal Donor Livers.

🎖️ Top 10% Journal

3 weeks ago • Ageing research reviews

Sticky Cell Properties in Aging: New Physical Insights and Possible BiomarkersCellular viscous properties in senescence: An emerging biophysical perspective and potential biomarker.

🥈 Top 2% Journal

3 weeks ago • Materials today. Bio

Energy supply and use reshape mitochondrial balance to support nerve repairFuel-maintenance coupling reprograms mitochondrial homeostasis to enable peripheral nerve regeneration.

🥉 Top 5% Journal

3 weeks ago • Journal of hazardous materials

Exposure to fluorescent nanoparticles during pregnancy may cause early aging of the placenta by changing protein activity in placenta cellsGestational exposure to PP-NPs promotes premature placental ageing through global reprogramming of the trophoblast phosphoproteome.

🥉 Top 5% Journal

3 weeks ago • Cell communication and signaling : CCS

Self-cleaning process in scar-forming kidney cells may promote cyst growth in inherited polycystic kidney diseaseMyofibroblast- specific autophagy drives cyst growth in autosomal dominant polycystic kidney disease.

🥉 Top 5% Journal

3 weeks ago • Ageing research reviews

Communication Between Mitochondria and Cell Stress Systems in Osteoarthritis: From Age-Related Cartilage Cell Problems to New TreatmentsMitochondrial-ER stress crosstalk in osteoarthritis: From ageing-associated chondrocyte dysfunction to emerging therapeutics.

🥈 Top 2% Journal

3 weeks ago • Cytokine & growth factor reviews

How aging cells contribute to fatty liver disease linked to metabolism problemsThe role of cellular senescence in metabolic dysfunction-associated steatotic liver disease.

🥉 Top 5% Journal

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Longevity & Aging Research Papers