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3 weeks ago • Nanomedicine (London, England)

How Tiny Particles Reach and Move Within the Brain in Nervous System Diseases: A Guide for TreatmentsBrain targeting and trafficking of extracellular vesicles in central nervous system diseases: a therapeutic roadmap.

📖 Top 50% Journal

3 weeks ago • Regulatory toxicology and pharmacology : RTP

Comparing Safety Tests of COVID-19 Vaccines in Laboratory and Human StudiesComparative analysis of non-clinical and clinical safety assessment of COVID 19 vaccines.

📖 Top 20% Journal

3 weeks ago • bioRxiv : the preprint server for biology

How IFNα2 changes immune and cancer cells to overcome colon cancer resistance to immunotherapyMulti-compartment immune and tumor cell reprogramming by IFNα2 overcomes colon cancer immunotherapy resistance.

3 weeks ago • Nature biotechnology

Efficient cytosine base editing inside living cells using virus-like particles that block uracil DNA repairEfficient in vivo cytosine base editing using virus-like particles with uracil DNA glycosylase inhibition.

🏆 Top 0.1% Journal

3 weeks ago • bioRxiv : the preprint server for biology

How a natural flu protein is processed and shown to immune cells using a T cell receptor-like antibodyGeneration and MHC class II loading of an endogenous influenza epitope revealed by a T cell receptor-like antibody.

3 weeks ago • bioRxiv : the preprint server for biology

Special Thyclotides Help Deliver Active Peptides Efficiently into CellsCell Penetrating Thyclotides Facilitate Efficient Delivery of Bioactive Peptides into Cells.

3 weeks ago • IUBMB life

Using Drug Lifespan to Target Short-Lived Long Noncoding RNAs with Antisense MoleculesHalf-Life as a Therapeutic Design Axis: Targeting Short-Lived lncRNAs With Antisense Oligonucleotides.

📖 Top 20% Journal

3 weeks ago • ACS omega

Smart Polyethylenimine-Based Carriers for Delivering siRNA: Current Approaches and Future DirectionsStimuli-Responsive Polyethylenimine Derivatives as Carriers for siRNA Delivery: Current Solutions and Future Perspectives.

📖 Top 30% Journal

3 weeks ago • Journal of chromatography. A

Detecting charged fats in horse blood to monitor mRNA drug useDetection of ionisable lipids in equine plasma by supported liquid extraction and liquid chromatography-high-resolution tandem mass spectrometry for doping control of mRNA agents.

📖 Top 30% Journal

3 weeks ago • Advanced materials (Deerfield Beach, Fla.)

Self-Boosting RNA Vaccine Reduces Immune Resistance by Dendritic Cells to Improve Cell Therapy for Solid TumorsSelf-Cooperative RNA Vaccine Mitigates Dendritic Cell-Mediated Acquired Immune Resistance to Potentiate Cell Therapy for Solid Tumors.

🥇 Top 1% Journal

3 weeks ago • Biomaterials

Targeted delivery of optimized mRNA nanoparticles to lymph nodes for COVID-19 vaccinationLymph node-targeted mRNA delivery of fine-tuned peptide-nanocomplexes for SARS-CoV-2 Vaccination.

🥉 Top 5% Journal

3 weeks ago • Advanced drug delivery reviews

Lipid nanoparticles that release medicine in response to cell oxidationRedox-responsive LNPs for therapeutics delivery.

🥈 Top 2% Journal

3 weeks ago • Clinical epigenetics

Advances in epigenetic editing: AI-based design, improved delivery methods, and progress toward medical useEpigenetic editing approaches maturity: AI-driven precision design, delivery innovation, and the road to clinical translation.

🎖️ Top 10% Journal

3 weeks ago • Cell biomaterials

mRNA-based MRI agent for accurate diagnosis of brain tumors and treatment-related changesmRNA-based MRI contrast agent for precise diagnosis of glioma and pseudoprogression.

3 weeks ago • Biotechnology journal

Advances and Future Directions of Tiny Particle Delivery Systems for mRNA Vaccines Controlled by MetabolismProgress and Prospects of Nanodelivery Systems in Metabolism-Regulated mRNA Vaccines.

📖 Top 30% Journal

3 weeks ago • Molecular therapy : the journal of the American Society of Gene Therapy

How Gene Code Changes Affect Self-Replicating RNA’s Ability to Copy ItselfTransgene Sequence Codon Optimization and Composition Determines Replication Competence of Self-Amplifying RNA.

🥈 Top 2% Journal

4 weeks ago • ACS applied bio materials

Improved Gene Delivery Using Aminated Collagen-Chitosan Non-Viral CarriersMatrix-Enhanced Non-Viral Vectors: Aminated Collagen-Chitosan for Improved Gene Delivery.

📖 Top 20% Journal

4 weeks ago • Nucleosides, nucleotides & nucleic acids

Partial pairing between the ends of synthetic mRNA controls its expression levelsPartial base pairing between 5' and 3' UTRs artificially regulates IVT mRNA expression levels.

4 weeks ago • Proceedings of the National Academy of Sciences of the United States of America

mRNA lipid nanoparticle cancer vaccine delivering multiple immune activators to boost tumor-fighting responsemRNA lipid nanoparticle cancer vaccine platform delivering multiple STING activators for enhanced antitumor activity.

4 weeks ago • The Journal of investigative dermatology

The past and future of RNA-based medicinesHistory and future of RNA medicines.

🎖️ Top 10% Journal

4 weeks ago • Nature communications

Lung-delivered mRNA nanoparticle vaccines for fast and lasting protection against bacterial infectionsPulmonary mRNA-LNP vaccines for rapid and durable protection against bacterial infection.

🥈 Top 2% Journal

4 weeks ago • Communications biology

Engineered carriers deliver mRNA to skin for healing and regenerationBiologically engineered vectors enable topical mRNA delivery for skin regeneration.

🥉 Top 5% Journal

4 weeks ago • Communications medicine

The role of mRNA vaccine technology in helping Africa become independent in public healthThe strategic importance of mRNA vaccine technologies in Africa for achieving public health independence.

🥉 Top 5% Journal

4 weeks ago • Journal of the American Chemical Society

Ionizable Lipid Nanoparticles Activated by Tumor Acidity for Targeted Cancer TherapyTumor Acidity-Activatable Ionizable Lipid Nanoparticles for Selective Oncolytic Therapy.

🥇 Top 1% Journal

4 weeks ago • Journal of materials chemistry. B

Carefully designed tiny capsules for steady release of mRNA lipid nanoparticlesPrecise microfluidic engineering of mRNA lipid nanoparticle-loaded polycaprolactone microcapsules for sustained delivery.

📖 Top 20% Journal

4 weeks ago • ACS nano

A Lung-Directed T Cell Nanovaccine Links Lung Immune Activation to Bodywide Anti-Cancer Response in Non-Small-Cell Lung CancerA Lung-Targeted γδ T Cell Nanovaccine Couples Pulmonary Immune Priming to Systemic Antitumor Immunity in Non-Small-Cell Lung Cancer.

🥈 Top 2% Journal

4 weeks ago • PloS one

A Piezoelectric Device for Improved Delivery of RNA Vaccines Without CarriersA piezoelectric electroporator (Piezopen) for enhanced "naked" RNA vaccine delivery.

📖 Top 30% Journal

1 month ago • Journal of hematology & oncology

Design, cell delivery, and potential uses of antibody-linked DNA moleculesAntibody-oligonucleotide conjugates: design principles, intracellular delivery, and translational opportunities.

🥇 Top 1% Journal

1 month ago • NPJ vaccines

Immune response to the LP.8.1-adapted BNT162b2 COVID-19 vaccine in animal studiesPreclinical immunogenicity of the LP.8.1-adapted BNT162b2 COVID-19 vaccine.

🥉 Top 5% Journal

1 month ago • Advanced science (Weinheim, Baden-Wurttemberg, Germany)

mRNA Lipid Nanoparticle Vaccines Help Treat Autoimmune Disease in Animal ModelsAutoantigen mRNA-LNP Vaccination Drives Therapeutic Efficacy in Preclinical Models for Autoimmunity.

🥈 Top 2% Journal

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