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2 weeks ago • Molecular neurobiology

Withaferin A's potential protective effects in Huntington's disease: current findings and future outlookNeuroprotective Role of Withaferin A in Huntington's Disease: Current Evidence and Future Perspectives.

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2 weeks ago • Inflammopharmacology

Resveratrol supplements and their link to inflammation and oxidative stress in metabolic disorders: a review and dose analysis of clinical trialsEffects of resveratrol supplementation on inflammatory and oxidative stress biomarkers in metabolic disorders: a systematic review and dose-response meta‑analysis of randomized controlled trials.

📖 Top 20% JournalArticle

2 weeks ago • The Journal of nutritional biochemistry

Paeoniflorin May Protect Against Acute Kidney Injury by Boosting Mitochondrial Cleanup Through PRDX5 Inhibiting RACK1Paeoniflorin Promotes Mitophagy Against Acute Kidney Injury via PRDX5-Dependent Inhibition of RACK1.

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2 weeks ago • Advanced healthcare materials

Using Nano-Enhanced 3D Environments to Control Cell Vesicles for Reducing Cell Death and Supporting Muscle Repair in DiabetesMultimodal Programming of Extracellular Vesicles via Nano-Primed SECCS-Based 3D Microenvironments for Coordinated Ferroptosis Suppression and Myogenic Regeneration in Diabetes.

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2 weeks ago • Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology

Biomarker patterns that change with size in zebra mussels and what they mean for monitoring freshwater healthSize-dependent biomarker profiles in the zebra mussel Dreissena polymorpha: implications for freshwater biomonitoring.

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2 weeks ago • International journal of biological macromolecules

Nicotinamide mononucleotide helps improve polycystic ovary syndrome by boosting energy use through activating a protein that changes lactate dehydrogenaseNicotinamide mononucleotide supplementation improves polycystic ovary syndrome by activating silent regulatory protein 2 mediated lactate dehydrogenase A lysine 119 deacetylation to enhance glycolytic activity.

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2 weeks ago • Frontiers in pharmacology

Natural products affecting mitochondrial balance through movement, recycling, drug behavior, and safetyNatural products targeting mitochondrial homeostasis: a four-dimensional framework integrating dynamics, mitophagy, pharmacokinetics, and translational safety.

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2 weeks ago • iMetaOmics

Biological Age and How Activity, Sleep, and Diet Together Influence Healthy AgeingBiological age in the meta omics era: Integrating physical activity, sleep, and diet to reshape paths of healthy ageing.

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2 weeks ago • Frontiers in cell and developmental biology

How Angelica Pubescens-Taxillus Chinensis compounds may help relieve spine disc damage caused by pressure through the piezo1/NF-κB signaling pathwayMechanistic study on components of Angelica Pubescens-Taxillus Chinensis in improving compression-induced intervertebral disc degeneration via piezo1/NF-κB signaling axis.

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2 weeks ago • Frontiers in immunology

Immune and inflammation links to cell death and heart scarring genes in heart failure with preserved pumpingImmune and inflammatory features associated with pyroptosis- and myocardial fibrosis-related genes in HFpEF: a machine learning study.

🥉 Top 5% JournalArticle

2 weeks ago • Frontiers in cellular neuroscience

Immune Cells in the Ear and Their Role in Age-Related Hearing Loss: Inflammation and Potential TreatmentsThe cochlear macrophage in presbycusis: inflammaging, neuroinflammation, and targets for therapeutic modulation.

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2 weeks ago • RSC chemical biology

Using NAD+-like molecules to understand how PARP enzymes add ADP-ribose in cellsNAD+ analogues for decoding the biological chemistry of PARP-mediated ADP-ribosylation.

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2 weeks ago • Aesthetic surgery journal

Possible roles of NAD+ in cosmetic plastic surgery: A review of current evidenceDoes NAD+ Have a Role in Aesthetic Plastic Surgery? An Evidence-Based Review.

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2 weeks ago • Frontiers in nutrition

How intermittent fasting may affect metabolism through gut bacteria, body clocks, and cell cleanupChrononutritional regulation of metabolic homeostasis: intermittent fasting through gut microbiota, circadian rhythms, and autophagy.

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2 weeks ago • Journal of inflammation research

How Mitochondria and Immune Cells Interact During Sepsis at Different Stages: Linking Metabolic Changes, Organ Damage, and Treatment OptionsMitochondria-Macrophage Interactions in Sepsis at Different Immune Stages: Integrating Immunometabolic Reprogramming, Organ Damage, and Therapeutic Strategies.

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2 weeks ago • FASEB journal : official publication of the Federation of American Societies for Experimental Biology

A protein in blood vessel cells may reduce cell aging and fat buildup to protect against artery disease in miceEndothelial Matrin-3 Limits Cellular Senescence and Lipid Dysregulation to Protect Against Murine Atherosclerosis.

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2 weeks ago • Biology

Milk Protein Peptides Reduce Immune Aging and Inflammation in an Aging Mouse ModelCasein Hydrolysate Peptides Attenuate Immunosenescence and Inflammaging in a D-Galactose-Induced Mouse Model of Aging.

📖 Top 20% JournalFulltext (Open License)Article

2 weeks ago • International journal of molecular sciences

How Mitochondrial Cleanup and Iron-Related Cell Death May Work Together in Kidney Tubule Damage from DiabetesMitophagy and Ferroptosis in Diabetic Kidney Disease: A Hypothesis of Their Synergistic Interplay in Renal Tubular Injury-A Narrative Review.

📖 Top 20% JournalFulltext (Open License)Article

2 weeks ago • International journal of molecular sciences

Piceatannol selectively kills chemotherapy-induced senescent colon cancer cells by disrupting their energy and triggering cell deathCorrection: Ambrosino et al. Selective Senolysis of 5FU-Induced CRC Senescent Cells by Piceatannol Through Mitochondrial Depolarization and AIF-Dependent Apoptosis. Int. J. Mol. Sci. 2025, 26, 9134.

📖 Top 20% JournalPublished Erratum

2 weeks ago • International journal of molecular sciences

Slow Release and Active Effects of Combined Quercetin and Resveratrol Carriers in Hummus During Simulated DigestionDual-Loaded Quercetin-Resveratrol Niosomes: Sustained In Vitro Release and Retained Bioactivity in Hummus During Simulated Gastrointestinal Digestion.

📖 Top 20% JournalFulltext (Open License)Article

2 weeks ago • International journal of molecular sciences

Gastrodin’s role in controlling microglial self-cleaning and inflammatory cell death through the energy and inflammation pathwaysGastrodin and Microglial Autophagy-Pyroptosis Crosstalk: Evidence and Hypotheses Involving the AMPK/mTOR/NLRP3 Axis.

📖 Top 20% JournalFulltext (Open License)Article

2 weeks ago • International journal of molecular sciences

Using Network Analysis to Understand How Plant Compounds Work on Multiple Targets: Combining Molecular Studies, Lab Tests, and Clinical ApplicationsNetwork Pharmacology-Guided Phytochemical Polypharmacology: Integrating Molecular Mechanisms, Experimental Validation and Clinical Translation.

📖 Top 20% JournalFulltext (Open License)Article

2 weeks ago • Aging cell

MTR4: A Key Protein Supporting Healthy Blood Vessel Lining in Young TissueMTR4: A Conserved Youth Factor for Vascular Endothelium.

🥉 Top 5% JournalArticle

2 weeks ago • International journal of molecular sciences

Ciprofloxacin causes oxidative stress that leads to aging-like changes in human skin cells grown in the labCiprofloxacin-Induced Oxidative Stress Promotes a Senescence-like Phenotype in Human Fibroblasts In Vitro.

📖 Top 20% JournalFulltext (Open License)Article

2 weeks ago • Cells

Activating Mitochondrial Fusion Slows Aging in Nematode WormsMitofusin Activation Delays Aging in Caenorhabditis elegans.

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2 weeks ago • Journal of reproductive immunology

High glucose levels may cause problems in placental cell invasion by increasing cell aging and IGFBP4 signalingElevated glucose levels trigger trophoblast cell invasion dysfunction through enhanced senescence and IGFBP4 signaling pathway.

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2 weeks ago • Cells

Disrupting Energy Control in Cells by the TBC1D15 ProteinDisrupting Mitochondrial Homeostasis via TBC1D15 Protein.

🎖️ Top 10% JournalFulltext (Open License)Article

2 weeks ago • International journal of molecular sciences

Biological Effects of 3-Hydroxypyridine Compounds Combined with Natural IngredientsBiological Activity of 3-Hydroxypyridine Derivatives with Natural Components.

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2 weeks ago • Animals : an open access journal from MDPI

Effects of Pollen Substitute Diets on Honey Bees’ Gene Activity, Immune Health, and SurvivalIntegrated Assessment of Pollen Substitute Diets in Honey Bees Based on Transcriptional Responses, Immune-Derived Predicted Biological Age, and Survival.

📖 Top 30% JournalArticle

2 weeks ago • Molecules (Basel, Switzerland)

New Treatments Targeting Sirtuins for Healthy Thinking in Aging and Possible Benefits for Alzheimer's DiseaseTargeting Specific Sirtuin Modulation: Emerging Therapeutic Strategies for Healthy Cognitive Ageing and Potential Implications for Alzheimer's Disease.

📖 Top 20% JournalArticle

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