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2 weeks ago • British journal of pharmacology

β-Nicotinamide mononucleotide reduces liver damage from aflatoxin B1 through gut bacteria, bile acids, and the FXR receptorβ-Nicotinamide mononucleotide reduces aflatoxin B1 induced liver injury via the gut microbiota-bile acid-farnesoid X receptor (FXR/NR1H4) axis.

2 weeks ago • JCI insight

Gut bacteria products influence helper T-cell development and immune aging in HIV-1 infectionMicrobiome-Derived Metabolites Shape CD4⁺ T-Cell Differentiation and Immune Aging in HIV-1 Infection.

🥉 Top 5% Journal

2 weeks ago • Molecular biology reports

circPVT1 helps protect hearing cells from aging caused by D-galactoseProtective effects of circPVT1 against D-galactose-induced senescence in HEI-OC1 auditory cells.

📖 Top 30% Journal

2 weeks ago • Reproductive biology and endocrinology : RB&E

Theca cells as key players in ovarian agingTheca cells: active orchestrators of ovarian aging.

📖 Top 20% Journal

2 weeks ago • Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Gut bacteria release ferulic acid from sprouted quinoa to reduce obesity-linked thinking problems by boosting waste removal in memory areas of the brainGut Microbial Release of Ferulic Acid From Germinated Quinoa Alleviates Obesity-Associated Cognitive Impairment by Activating Hippocampal Mitophagy Associated with PINK1/Parkin Pathway.

🥈 Top 2% Journal

2 weeks ago • BMC pregnancy and childbirth

📖 Top 20% Journal

2 weeks ago • Neurochemical research

Fat Imbalance Causes Brain Mitochondria Problems That Don’t Reach Disease Levels in ApoE-Deficient MiceDyslipidemia-Induced Mitochondrial Dysfunctions in the Brains Does Not Reach Pathological Levels in the ApoE-Knockout Mice.

📖 Top 20% Journal

2 weeks ago • Annual review of genetics

How Cells Detect and Respond to NutrientsDesign Principles and Architecture of Cellular Nutrient Signaling.

🥇 Top 1% Journal

2 weeks ago • American journal of epidemiology

How the length, timing, and level of neighborhood poverty from adolescence to early middle age relate to biological agingNeighborhood poverty duration, timing, and severity from adolescence to early midlife and biological aging.

🥉 Top 5% Journal

2 weeks ago • Cellular and molecular neurobiology

Monomethyl Fumarate's effects on iron use and energy production in brain immune cells linked to multiple sclerosis progressionMonomethyl Fumarate Modulates Iron Metabolism and Mitochondrial Function in Microglia with Implications for Multiple Sclerosis Progression.

📖 Top 20% Journal

2 weeks ago • The EMBO journal

Atg23 stops incorrect merging of Atg9 transport vesicles when delivering materials to autophagosome formation sitesAtg23 prevents aberrant fusion of Atg9 vesicles during delivery to autophagosome formation sites.

🥇 Top 1% Journal

2 weeks ago • Journal of applied physiology (Bethesda, Md. : 1985)

Effects of 8 Weeks of Short Exercise Sessions on Muscle Oxygen Use, Heart and Metabolism Health, Mitochondria, and Early Artery Disease Signs in Inactive WomenEffects of 8-Week Exercise Snacks on Muscle Oxygenation and Cardiometabolic, Mitochondrial and Subclinical Atherosclerosis Markers in Sedentary Women.

📖 Top 20% Journal

2 weeks ago • Colloids and surfaces. B, Biointerfaces

pH-sensitive chitosan nanoparticles for targeted delivery of nicotinamide mononucleotide in treating acute kidney injurypH-responsive chitosan-based nanoparticles for targeted delivery of nicotinamide mononucleotide in acute kidney injury therapy.

📖 Top 20% Journal

2 weeks ago • Metabolic brain disease

Using neural networks to study cell death and treatment options in early-onset Alzheimer's diseaseNeural network-enhanced investigation of ferroptosis and druggability in early-onset alzheimer's disease.

📖 Top 20% Journal

2 weeks ago • Advanced materials (Deerfield Beach, Fla.)

Nanoparticles that deliver protons and electrons together may restore energy production and help bone regrow during agingPCET-Inspired Nanoparticles Enable Paired Proton-Electron Delivery to Restore Mitochondrial Electron Transport and Regenerate Bone During Aging.

🥇 Top 1% Journal

2 weeks ago • Gene

Common genetic routes and gene interactions in major brain diseases that cause nerve cell lossExploring shared genetic pathways and gene interplay in major neurodegenerative diseases: a comprehensive review.

2 weeks ago • Reproductive sciences (Thousand Oaks, Calif.)

Using Data Analysis and Testing to Identify Two Mitophagy-Related Proteins as Diagnostic and Treatment Targets in Polycystic Ovary SyndromeBioinformatics, Machine Learning and Functional Validation Reveal Mitophagy-Related FABP5 and HMOX1 as Diagnostic and Therapeutic Targets in Polycystic Ovary Syndrome.

📖 Top 20% Journal

2 weeks ago • American journal of respiratory cell and molecular biology

High oxygen levels in newborns may cause aging of immune cells and lung damage through a stress-related protein pathwayNeonatal hyperoxia promotes macrophage senescence and lung injury via a p38MAPK-dependent secretome.

🎖️ Top 10% Journal

2 weeks ago • Drugs & aging

Bronchiectasis in Older Adults: Unique Causes, Diagnosis, and Disease Progress Compared to Younger PeopleBronchiectasis in Older Adults: Distinctive Epidemiology, Etiology, Diagnosis, and Clinical Evolution Compared with Younger Populations.

📖 Top 20% Journal

2 weeks ago • Progress in neuro-psychopharmacology & biological psychiatry

Antidepressants may help treat Alzheimer's and Parkinson's by reducing brain inflammationUnlocking new uses: The promise of antidepressants in treating Alzheimer's and Parkinson's through Neuroinflammation modulation.

2 weeks ago • npj aging

Intermittent chloroquine treatment extends lifespan, prevents breast tissue overgrowth, and lowers harmful blood fats and growth protein levels in female ratsIntermittent chloroquine treatment extends lifespan and prevents mammary hyperplasia in female rats while reducing serum ldl and igfbp3 levels.

🥉 Top 5% Journal

2 weeks ago • Epigenomics

How DNA methylation data cleaning and removed values affect epigenetic age estimatesDNA methylation quality control decisions, removed beta values, and their influence on epigenetic clocks.

📖 Top 30% Journal

2 weeks ago • Cureus

How CPT2 Connects Age-Related Brain Gene Changes to NMN-Driven Gene Activity Recovery in Metabolic OrgansCPT2 as a Convergent Node Linking Age-Associated Neuronal H3K27me3 Remodeling to Nicotinamide Mononucleotide (NMN)-Induced Expression Rescue in Metabolic Tissues.

2 weeks ago • Cureus

DNA Methylation of Key Glutamate Receptor Genes Shows Aging Patterns in Blood After COVID, Linked to Long-COVID Brain and Mood SymptomsDNA Methylation at Core N-Methyl-D-Aspartate (NMDA) Receptor Genes Reveals a Glutamatergic Signature of Aging in Post-COVID Whole Blood With Implications for Long-COVID Neuropsychiatric Sequelae.

2 weeks ago • Biochemical pharmacology

Gut bacteria patterns linked to lifespanMolecular signatures of the gut microbiota that affect longevity.

2 weeks ago • Diabetes, obesity & metabolism

Metformin may improve diabetes-related memory problems by helping cells clear damaged mitochondria through p53 and Parkin pathwaysMetformin Ameliorates Diabetes-Associated Cognitive Dysfunction via p53/Parkin-Mediated Mitophagy.

2 weeks ago • Ageing research reviews

Blood as a Key Link for Treatments Targeting AgingThe circulating senosome: Blood as the therapeutic interface of aging.

🥈 Top 2% Journal

2 weeks ago • Naunyn-Schmiedeberg's archives of pharmacology

Fisetin reduces nerve cell damage caused by glutamate and influences growth of new brain cells in the labFisetin attenuates glutamate-induced excitotoxicity and modulates neural progenitor cell dynamics in vitro.

📖 Top 30% Journal

2 weeks ago • Pharmacological research

Frailty as a problem with how energy systems adapt, from energy overload to overall weaknessRethinking frailty as a disorder of mitochondrial adaptability, from energetic congestion to systemic vulnerability.

🥉 Top 5% Journal

2 weeks ago • Journal of nanobiotechnology

Microspheres that remove harmful molecules and carry cell signals to treat spinal disc degenerationROS-scavenging microspheres loaded with extracellular vesicles for intervertebral disc degeneration therapy.

🥉 Top 5% Journal

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