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2 weeks ago • Metabolic brain disease

Resveratrol-enriched stem cell exosomes in a lab model of Parkinson’s diseaseExploring the potential of resveratrol-enriched cord mesenchymal stem cell derived exosomes in an in vitro Parkinson's model.

📖 Top 20% JournalArticle

2 weeks ago • Molecular genetics and genomics : MGG

HuR influences disease-related gene changes linked to Alzheimer's, including MAPTHuR modulates disease-relevant alternative splicing of MAPT and other Alzheimer's disease-related genes.

📖 Top 50% JournalArticle

2 weeks ago • Ageing research reviews

How heart and brain age together: different patterns, underlying molecular causes, and possible treatmentsHeart-brain co-ageing: Phenotypic heterogeneity, molecular mechanisms and translational interventions.

🥈 Top 2% JournalArticle

2 weeks ago • Molecular neurobiology

Restoring Brain Balance by Modulating Class II HDAC Proteins: Mechanisms and Treatment PossibilitiesRestoring Neural Homeostasis via Class II HDAC Modulation: Mechanistic Insights and Therapeutic Opportunities.

🎖️ Top 10% JournalArticle

2 weeks ago • Cell metabolism

A fat tissue signal controlled by NAD+ helps protect muscles from wastingAn NAD+-responsive adipose signal coordinates inter-organ defense against muscle atrophy.

🥇 Top 1% JournalArticle

2 weeks ago • Drug design, development and therapy

New Insights into Schaftoside: How It Works, Moves Through the Body, and Its Treatment PotentialAdvances in Schaftoside Research: Pharmacological Mechanisms, Pharmacokinetics, and Therapeutic Perspectives.

📖 Top 20% JournalArticle

2 weeks ago • MedComm

MicroRNA-708 Activated by AMPK May Slow Cell Aging by Reducing Disabled-2 and mTORC1 ActivityCorrection to "AMPK-upregulated microRNA-708 Plays as a Suppressor of Cellular Senescence and Aging via Downregulating Disabled-2 and mTORC1 Activation".

🥉 Top 5% JournalPublished Erratum

2 weeks ago • Pharmacological research

How Cell Stress and Energy Problems Interact in Inflammatory Bowel Disease and Possible TreatmentsInterplay Between Endoplasmic Reticulum Stress and Mitochondrial Dysfunction in Inflammatory Bowel Disease: From Molecular Mechanisms to Therapeutic Opportunities.

🥉 Top 5% JournalArticle

2 weeks ago • European journal of pharmacology

Rapamycin's possible role in neural tube defects based on computer analysis and lab experimentsThe role of rapamycin in neural tube defects: insights from bioinformatics analysis and experimental validation.

📖 Top 20% JournalArticle

2 weeks ago • Environmental pollution (Barking, Essex : 1987)

Short-term ozone exposure causes lung problems in older mice shown by multiple biological analysesAcute ozone exposure induced lung impairments in aged mice: multi-omics evidence.

🥉 Top 5% JournalArticle

2 weeks ago • Journal of advanced research

Removal of damaged mitochondria and cell cleanup in heart damage caused by doxorubicin: how they interact and potential treatmentsMitophagy and ER-phagy in doxorubicin-induced cardiotoxicity: mechanisms, crosstalk, and therapeutic implications.

🥉 Top 5% JournalArticle

2 weeks ago • Pharmacological research

How Fat Storage Structures and Energy Centers Work Together and Their Roles in DiseasesMechanisms of lipid droplet-mitochondria interactions and their roles in diseases.

🥉 Top 5% JournalArticle

2 weeks ago • The Journal of biological chemistry

EPG5 controls iron storage by regulating two steps in the breakdown of large iron-storage complexesEPG5 orchestrates iron compartmentalization through dual regulation in macroferritinophagy.

🎖️ Top 10% JournalArticle

2 weeks ago • Science advances

A Hydrogel System for Spinal Disc Repair by Targeting Cell Energy Centers and Boosting Cell CleanupA "Progenitor Cell Ark" hydrogel system for intervertebral disc regeneration via mitochondrial targeting and mitophagy enhancement.

🥈 Top 2% JournalArticle

2 weeks ago • Ecotoxicology and environmental safety

Vitamin C may reduce air pollution-related thyroid problems and cell cleanup imbalance by restoring calcium balance between cell compartmentsVitamin C attenuates PM2.5-induced thyroid dysfunction and mitophagy dysregulation by rebalancing ER-mitochondrial Ca²⁺ dynamics.

🎖️ Top 10% JournalArticle

2 weeks ago • Biogerontology

Hippo-YAP/TAZ signaling in brain aging and neurological disorders: key mechanisms, interactions, and treatment possibilitiesHippo-YAP/TAZ signalling at the crossroads of brain ageing and neurological disorders: mechanisms, crosstalk, and therapeutic prospects.

📖 Top 20% JournalArticle

2 weeks ago • International journal of pharmaceutics: X

Near-infrared activated prodrug that coordinates heat shock protein and drug resistance responses with impaired mitochondrial cleanup to overcome natural heat toleranceRedox-metabolic cascade NIR-II prodrug for synchronizing compensatory HSPs/P-gp feedback with mitophagy flux impairment against intrinsic thermotolerance.

📖 Top 20% JournalArticle

2 weeks ago • Developmental cell

Mitochondria trigger two processes that cause cells to release aging-related signalsMitochondria strike two hits to drive the SASP.

🥇 Top 1% JournalComment

2 weeks ago • FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Neferine may protect against rat osteoarthritis by increasing cell cleanup processesNeferine Exerts a Protective Effect on Rat Osteoarthritis by Upregulating Autophagy.

Article

2 weeks ago • Current drug targets

Computer Study of Hydnocarpin as a New ROCK2 Blocker and Possible Controller of Cell Cleanup in CancerComputational Evaluation of Hydnocarpin as a Novel ROCK2 Inhibitor and Potential Regulator of Mitophagy in Cancer.

📖 Top 30% JournalArticle

2 weeks ago • Tissue & cell

Combined effects of resveratrol and nicotinamide on growth, cell death, and SIRT1 gene activity in human eye support cellsThe synergistic effects of resveratrol and nicotinamide on cell proliferation, apoptosis, and SIRT1 gene expression in human retinal pigment epithelial cells.

📖 Top 30% JournalArticle

2 weeks ago • European journal of pharmacology

Ibogaine may support brain cell repair and flexibility by changing cell metabolismExtracellular flux analysis and proteomic profiling indicate ibogaine promotes synaptic plasticity and neural repair by a metabolic preconditioning mechanism.

📖 Top 20% JournalArticle

3 weeks ago • Leukemia

Blocking a specific cell cleanup process may improve venetoclax treatment in acute myeloid leukemiaInhibition of PHB2/PINK1-mediated mitophagy potentiates venetoclax activity in acute myeloid leukemia.

🥈 Top 2% JournalArticle

3 weeks ago • Reproduction (Cambridge, England)

Nicotinamide mononucleotide helps cow embryos develop by improving energy production in early-stage cellsNicotinamide mononucleotide supports the development of bovine embryo through enhancement of mitochondrial function in morula.

Article

3 weeks ago • iScience

Applying urolithin A to the skin may boost cell cleanup and energy production to help skin age betterTopical application of urolithin A activates mitophagy and enhances mitochondrial function to promote skin longevity.

🎖️ Top 10% JournalArticle

3 weeks ago • Biochemical Society transactions

How Fasting and Diet May Increase Cell Cleaning: Separating Truth from MythsIncreasing autophagy with fasting and diet: separating fact from fiction.

🎖️ Top 10% JournalArticle

3 weeks ago • Pharmacology & therapeutics

Molecular causes of natural heart pacemaker problems, resulting irregular heartbeats, and paths toward targeted treatmentsSinoatrial node dysfunction: molecular mechanisms, arrhythmogenesis, and translational pathways toward precision therapy.

Article

3 weeks ago • Neuroscience and biobehavioral reviews

How Older Parents May Influence Their Children's Aging, Lifespan, and Risk of Brain DiseasesThe intergenerational clock: How advanced parental age shapes offspring biological aging, longevity and neurodegenerative risk.

🥉 Top 5% JournalArticle

3 weeks ago • Molecular and cellular biochemistry

Exercise may improve heart failure by controlling heart cell cleanup through the ILF3/lncRNA NEAT1 pathwayExercise improves heart failure by regulating cardiomyocyte autophagy via the ILF3/lncRNA NEAT1 axis.

Article

3 weeks ago • American journal of lifestyle medicine

Using Lifestyle Changes to Improve Health in People with Intellectual and Developmental DisabilitiesApplying Lifestyle Medicine to Improve Health Outcomes in People With Intellectual and Developmental Disabilities.

📖 Top 30% JournalArticle

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