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1 week ago • Journal of community genetics

Public understanding, opinions, and ethics of gene editing for inherited diseases in Taif, Saudi ArabiaPublic knowledge, attitudes, and ethical views on CRISPR-Cas9 gene editing for genetic diseases in Taif, Saudi Arabia.

📖 Top 30% JournalArticle

1 week ago • Insects

How the Fruit Fly Helps Us Understand Human DiseaseCredit to the Fruit Fly: How the Tiny Insect Lights Up Our Understanding of Human Disease.

📖 Top 30% JournalArticle

1 week ago • Human gene therapy

Comparing CRISPR-Cas9 Off-Target Prediction Tools Reveals Their Limits and Impact on Early TestingSystematic Benchmarking of CRISPR-Cas9 Off-Target Prediction Tools Reveals Limitations and Implications for Preclinical Assessment.

📖 Top 20% JournalArticle

1 week ago • Journal of microbiological methods

Fast and easy visual detection of Lawsonia intracellularis using a DNA-based test with CRISPR technologyRapid and visual detection of Lawsonia intracellularis via an RPA-CRISPR/Cas12a assay.

📖 Top 50% JournalArticle

1 week ago • Biosensors & bioelectronics

Using two-step DNA reactions and gene editing tools for clear electrochemical detection of the aflD gene and Aflatoxin B1Integration of dual-output TMSD and CRISPR/Cas12a for crosstalk-free electrochemiluminescence detection of aflD gene and AFB1.

🥉 Top 5% JournalArticle

1 week ago • Analytica chimica acta

A new CRISPR-based digital test for detecting the CD44 proteinConstruction of the CRISPR/Cas12a-digital integrated immunoassay technology for CD44 detection.

📖 Top 20% JournalResearch Support, Non-U.S. Gov't

1 week ago • Journal of fungi (Basel, Switzerland)

Fast CRISPR-based test for detecting grapevine black-foot disease pathogensA Rapid Recombinase Polymerase Amplification-CRISPR/Cas12a Assay for Detecting Grapevine Black-Foot Pathogens.

📖 Top 20% JournalArticle

1 week ago • Analytical chemistry

DNA Nanowire-Enhanced CRISPR Test Using Three-Step Signal Boosting for Sensitive Detection of Myeloperoxidase ActivityDNA Nanowire-Assisted CRISPR/Cas12a Triple Cascade Amplification for Sensitive Detection of Myeloperoxidase Activity.

🎖️ Top 10% JournalArticle

1 week ago • Biosensors & bioelectronics

Detecting viral proteases using enzyme-triggered CRISPR/Cas activationProteolysis-triggered CRISPR/Cas activation via cascaded enzyme switches for viral protease detection.

🥉 Top 5% JournalArticle

1 week ago • Expert opinion on investigational drugs

Gene therapy using CRISPR-Cas9 to treat hereditary angioedemaLonvoguran ziclumeran: a CRISPR-CAS9-based gene therapy for the treatment of hereditary angioedema.

📖 Top 20% JournalArticle

1 week ago • Antonie van Leeuwenhoek

How Bacteria Defend Themselves Against VirusesBacterial immune systems.

📖 Top 50% Journal

1 week ago • Neuroprotection (Chichester, England)

Prime editing for neuropsychiatric disorders: Choosing mutation targets and moving toward clinical usePrime editing in neuropsychiatric disorders: From mutation-specific target selection to clinical translation.

📖 Top 50% Journal

1 week ago • Horticulture research

Improving DNA base editing in potatoes by combining multiple optimizationsBoosting cytosine base editing in potato through synergistic optimization.

🥉 Top 5% Journal

1 week ago • Microbial pathogenesis

Roles of two bacterial proteins in Mycobacterium avium survival inside cow immune cells using gene interferenceRoles of mdh and MAP1981c in Mycobacterium avium subsp. paratuberculosis intracellular survival within bovine monocyte-derived macrophages via CRISPR interference.

📖 Top 30% Journal

1 week ago • Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Precise placement of split CRISPR activators improves sensitive detection of microRNA and classification of cancer cellsSystematic Position Mapping of Split CRISPR-Cas12a Activators Enables Highly Sensitive miRNA Detection and Cancer Cell Stratification.

🥈 Top 2% Journal

1 week ago • The CRISPR journal

Changing Use Patterns of Advanced CRISPR Tools Shared by AddgeneThe Diversifying Distribution Trends of Maturing CRISPR Technologies by Addgene.

🎖️ Top 10% Journal

1 week ago • The CRISPR journal

Creating and Testing RNA-Guided Modular Base Editors Using Staphylococcus aureus Cas9 Variants and New EnzymesDevelopment and Characterization of RNA Aptamer-Mediated Modular Base Editors Containing Staphylococcus aureus Cas9 Derivatives and Novel Deaminase Orthologs.

🎖️ Top 10% Journal

2 weeks ago • Nature

Accurate DNA base editing guided by AlphaFold3 protein contact predictionsPrecise DNA base editing using AlphaFold3-based contact modelling.

2 weeks ago • Med (New York, N.Y.)

Ethical issues in gene therapyEthics of gene therapy.

🥈 Top 2% Journal

2 weeks ago • Cell genomics

Using base editing for precise medical treatmentsBase editing for precision therapeutics.

🥇 Top 1% Journal

2 weeks ago • Lab animal

Creation and description of mice with human-like CD4 immune proteinGeneration and characterization of humanized CD4 knock-in mice expressing chimeric mouse/human CD4 protein.

2 weeks ago • Biosensors & bioelectronics

Improved RNA detection using CRISPR/Cas12a with chemical additivesChemical additives-enhanced CRISPR/Cas12a-based RNA detection.

🥉 Top 5% Journal

2 weeks ago • ACS sensors

Color-based detection of viral and non-coding RNAs using CRISPR and zinc finger-guided gold nanoparticle assemblyCut-and-Bind Colorimetric Detection of Viral and Non-Coding RNAs Using CRISPR/Cas12a with Zinc Finger-Facilitated Gold Nanoparticle Assembly.

🎖️ Top 10% Journal

2 weeks ago • Nature

CRISPR-Cas controls activity of built-in anti-virus defense systemsCRISPR-Cas regulates expression of embedded anti-phage defence systems.

2 weeks ago • Blood advances

Modifying Stem Cells to Protect Them from Immune Attacks After TransplantEditing Around the Target: Epitope Engineering to Protect Stem Cell Grafts.

🥉 Top 5% Journal

2 weeks ago • Nature protocols

Studying large-scale genome structure by using targeted rearrangements through multiple precise edits in repeated DNA regionsLarge-scale genome structure interrogation via recombinase-mediated rearrangements of multiplexed prime edits in repetitive elements.

🥇 Top 1% Journal

2 weeks ago • Bioresource technology

Increasing natural pigment production in Chlorella sorokiniana by boosting the interaction between ORANGE and PSY proteinsEnhancing carotenoid production in Chlorella sorokiniana through the protein-protein interaction between ORANGE and PSY.

🥉 Top 5% Journal

2 weeks ago • Bioorganic & medicinal chemistry letters

Purifying guide RNA for gene editing without chromatographyNon-chromatographic purification of guide RNA for gene-editing experiments.

📖 Top 50% Journal

2 weeks ago • Cytotherapy

Non-viral gene editing with platinum TALEN helps produce large amounts of cancer-targeting T cellsPlatinum TALEN-mediated nonviral gene editing facilitates clinical-scale production of cancer antigen-reactive T cells.

📖 Top 20% Journal

2 weeks ago • Molecular therapy : the journal of the American Society of Gene Therapy

Using base editors to precisely add and remove genes at the same time to create allo-CAR T cells with fewer DNA rearrangementsRepurposing base editors for targeted knock-in and simultaneous multiplex knockouts to generate allo-CAR T cells with minimal translocations.

🥈 Top 2% Journal

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