Latest Psychedelic Science Research Papers | OpenScience.ink

yesterday • Progress in neuro-psychopharmacology & biological psychiatry

Serotonin-targeting psychedelics and amphetamine change male rats’ high-frequency calls toward sounds linked to positive feelingsSerotonergic psychedelics and amphetamine shift male rat ultrasonic vocalizations toward call patterns associated with positively valenced states.

Article

yesterday • Frontiers in chemistry

Computer modeling of a new remiketamine-like drug and related compounds: how they interact with NMDA receptors and a key metabolic enzymeStructure-based molecular modeling of a novel S-Remiketamine scaffold and derived arylcyclohexanone analogues: NMDA receptor dynamics, MM-GBSA ranking, and CES1-Oriented structural compatibility.

📖 Top 30% JournalArticle

yesterday • Se pu = Chinese journal of chromatography

Measuring three tryptamines in foods using advanced liquid chromatography and mass spectrometry[Simultaneous determination of three tryptamines in foods by ultra performance liquid chromatography-tandem mass spectrometry coupled with hydrophilic column separation].

English Abstract

yesterday • Frontiers in psychiatry

Best practice advice for psychiatrists using short-term oral, under-the-skin, and nasal ketamine treatments for depressionShort-term ketamine interventions for depressive disorders: practical best-practice recommendations for psychiatrists using oral, subcutaneous, and nasal formulations.

📖 Top 20% JournalArticle

yesterday • Journal of pain and symptom management

Views and Feelings About Psilocybin Therapy Among Underrepresented People with CancerPerceptions and Attitudes on Psilocybin-Assisted Therapy among Underrepresented People with Cancer.

Article

yesterday • Journal of psychopharmacology (Oxford, England)

Validating and creating a short version of a questionnaire measuring lasting positive and negative effects of psychedelic experiencesValidating and creating a short-form of the persisting effects questionnaire: A measure of positive and negative outcomes from psychedelic experiences.

Article

2 days ago • Nature communications

How Activation of 5-HT2A Receptors Differs from 5-HT2B ReceptorsMechanistic Basis for 5-HT2AR Over 5-HT2BR Activation.

🥈 Top 2% JournalArticle

2 days ago • Molecular psychiatry

Psilocybin improves social curiosity in male mice lacking SAPAP3 and activates thinking and memory brain areasPsilocybin restores social novelty investigation in male SAPAP3 knockout mice and engages prefrontal-hippocampal circuitry.

🥈 Top 2% JournalArticle

2 days ago • Nature communications

Designing psychedelic-like compounds that selectively target specific brain receptor typesStructure-based design of subtype-selective psychedelic analogs.

🥈 Top 2% JournalArticle

2 days ago • Revue medicale suisse

Using intravenous ketamine for patients in a suicidal crisis: when and how they are referred[Intravenous ketamine in suicidal crisis : indications and patient referral].

English Abstract

2 days ago • Npj mental health research

High ventilation breathwork as a non-pharmacological model for inducing psychedelic-like states: expert evaluations of therapeutic potential and risk.High ventilation breathwork as a non-pharmacological model for inducing psychedelic-like states: expert evaluations of therapeutic potential and risk.

Article

3 days ago • Frontiers in neuroscience

What Brain Flexibility Means in Mental Health and How Psychedelic Therapy May Relate to ItOn the meaning of "plasticity" in neuroscience and mental health research and its relation to the action of psychedelic therapy.

📖 Top 20% JournalArticle

3 days ago • Journal of clinical pharmacology

How Ketamine Dose and Treatment Length Relate to Internalizing Mental Health DisordersKetamine Dose and Duration Effects in Internalizing Disorders.

Randomized Controlled Trial

3 days ago • JAMA psychiatry

Why Stronger Blinding Is Needed in Psychedelic Drug StudiesThe Case for More Aggressive Masking in Psychedelic Trials.

🥇 Top 1% JournalArticle

3 days ago • Journal of psychiatric research

Clinical factors linked to low life engagement in people with treatment-resistant depression who don’t respond to ketamineClinical correlates of non-responders to ketamine in terms of self-assessed life engagement among treatment-resistant depression patients.

Article

3 days ago • Frontiers in psychiatry

How letting go, distancing, and rethinking relate to psilocybin response in hard-to-treat OCDSurrender, disidentification, and reappraisal: a qualitative comparison of psilocybin responders and non-responders in treatment-resistant OCD.

📖 Top 20% JournalArticle

4 days ago • Molecules (Basel, Switzerland)

Comparing the Safety and Effectiveness of Mushroom-Based and Plant-Based Treatments for Mental HealthSafety and Efficacy of Natural and Conventional Psychiatric Treatments: A Comparative Review of Mushroom-Derived Compounds and Medicinal Plants in the Management of Mental Disorders.

📖 Top 20% JournalArticle

4 days ago • Chinese medical journal

Psilocybin can reduce fear and promote brain plasticity in mice without activating 5-HT2A receptors5-HT2A receptor activation is dispensable for psilocybin-induced fear extinction and neuroplasticity in mice.

Article

4 days ago • Psychopharmacology

How Psychedelic Therapy May Reset Memory Storage to Help Anxiety DisordersResetting the hippocampal buffer: a neurocognitive account of psychedelic therapy for anxiety-related psychopathology.

📖 Top 20% JournalArticle

4 days ago • Scientific reports

Computer study of how dimethyltryptamine attaches to and is detected by metal-doped C20 fullereneIn silico insights into the adsorption and detection of dimethyltryptamine on metal doped C20 fullerene.

📖 Top 20% JournalArticle

4 days ago • Current biology : CB

Ketamine reduces activity in the brain’s aversion center during learning from negative outcomesKetamine attenuates habenula activity in response to aversive outcomes during Pavlovian learning.

Article

5 days ago • Cureus

Possible Effects of US FDA Approval of Psychedelic Drugs Like Ibogaine on Japanese PharmaciesImplications of Potential US FDA Approval of Psychedelics or Psychedelic-Adjacents Such as Ibogaine for Pharmacy in Japan.

Article

5 days ago • Journal of psychiatric practice

Psychiatric Drug Research Shifts from Symptom Groups to Targeted Brain Circuits and Personalized TreatmentsPsychopharmacology at an Inflection Point: From Syndromes to Stratified Mechanisms, Circuit-Based Treatments, and Precision Psychiatry.

Article

6 days ago • Annals of palliative medicine

Quick review of ketamine for easing depression and pain in advanced cancer patientsA rapid systematic review of palliative uses of ketamine for depression and pain in people living with advanced cancer.

Article

6 days ago • Orvosi hetilap

Using Psychedelic Drugs in Mental Health Treatment[The use of psychedelics in psychiatry].

English Abstract

1 week ago • Journal of psychoactive drugs

Psychedelic Experiences of Familiarity Compared to Personal Memories and Déjà VuCharacterizing Psychedelic-Evoked Familiarity: A Comparative Study with Autobiographical and Déjà Vu Experiences.

Article

1 week ago • Neuropharmacology

MDMA reduces alcohol drinking and changes pain-related gene activity in rats that prefer alcoholMDMA administration reduces ethanol drinking and is associated with altered nociceptin and dynorphin system gene expression in alcohol-preferring rats.

🎖️ Top 10% JournalArticle

1 week ago • Soins; la revue de reference infirmiere

How antidepressants, psychedelics, and talk therapies work in real-life mental health treatment[Antidepressants, psychedelics and psychotherapies: ecological validity and opacity in mental health].

English Abstract

1 week ago • JAMA

What Psilocybin IsWhat Is Psilocybin?

Article

1 week ago • HEC forum : an interdisciplinary journal on hospitals' ethical and legal issues

Ketamine-caused Dissociation as a Meaningful Sign, Not Just a Side Effect: How Context Guides Ethical Medical ResponsibilitiesKetamine-Induced Dissociation as an Ethical Signal, Not a Side Effect: Context as the Determinant of Clinical Duties Under Beneficence and Non-maleficence.

📖 Top 50% JournalArticle

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