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3 weeks ago • Brain and behavior

Psychedelics and Their Potential Benefits and Risks for Mental HealthPsychedelics in Mental Health: Opportunities and Challenges.

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4 days ago • Research square

Ketamine stays inside nerve cells long after it leaves the bloodstreamKetamine persists within neuronal compartments long after systemic clearance.

Preprint

1 week ago • Molecular neurobiology

Possible Biological Signs of Bipolar Disorder Progression and Their Links to Ketamine and Psychedelic TreatmentsCandidate Biomarkers of Bipolar Disorder Progression: Implications for Ketamine and Psychedelic Interventions.

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1 week ago • Psychopharmacology

Long-term low-dose psilocybin causes gene regulation changes in the thinking areas of rat brainsLong- term administration of low doses of psilocybin causes epigenetic changes in the rat medial prefrontal cortex.

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1 week ago • Therapeutic advances in psychopharmacology

Understanding how psychedelic clinical trials are designed and studiedConceptual analysis of mechanisms and methods in psychedelic clinical trial design: a narrative review.

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1 week ago • Neural computation

Brain Wave Interactions as a Basis for Evaluating Prediction ErrorsCross-Frequency Coupling as a Neural Substrate for Prediction Error Evaluation: A Laminar Neural Mass Modeling Approach.

📖 Top 30% JournalArticle

1 week ago • Addictive behaviors

Patterns and effects of using vaping and hallucinogens together: a review and analysisPatterns and implications of co-use between vaping and hallucinogens: a systematic review and meta-analysis.

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1 week ago • Cell reports

How GluN2D-targeting drugs and ketamine influence inhibitory signals, long-term brain strengthening, and motivationBidirectional control of vesicular GABA release, LTP, and amotivation by GluN2D-selective allosteric modulators and ketamine.

🥈 Top 2% Journal

1 week ago • Neuroscience and biobehavioral reviews

How serotonin-based psychedelics affect brain cells by increasing detailed context processingCellular mechanisms of serotonergic psychedelics - apical hypercontextualisation.

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2 weeks ago • British journal of clinical pharmacology

Psilocybin as a serotonin-based treatment for epilepsy: potential benefits and challengesPsilocybin as serotonergic therapy in epilepsy: Narrative review of potentials and limitations.

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2 weeks ago • European journal of pharmacology

Intranasal Ketamine Reduces Depression-Like Behaviors in Stressed Rats Linked to a Brain Energy EnzymeIntranasal ketamine alleviates depressive-like behaviors in chronic unpredictable mild stress rats in association with hypothalamic NADH:Ubiquinone oxidoreductase subunit A10.

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2 weeks ago • Psychopharmacology

How Psychedelic Research Became Influenced by Mystical IdeasThe mystic trip: how psychedelic research fell for mysticism.

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2 weeks ago • European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology

New drug and brain stimulation treatments for suicidal thoughts and actionsEmerging pharmacological and neuromodulation interventions for suicidal ideation and behaviour.

🥉 Top 5% Journal

2 weeks ago • Journal of affective disorders

Blood levels of brain growth protein after oral esketamine in hard-to-treat depression: Results from a placebo-controlled trialSerum brain-derived neurotrophic factor following oral esketamine in treatment-resistant depression: Results from a randomized placebo-controlled trial.

🥉 Top 5% Journal

3 weeks ago • The British journal of psychiatry : the journal of mental science

Psychedelic Therapy as a Possible Alternative to Assisted Suicide for Terminal Patients in the UKPsychedelic therapy at the end of life: unexplored alternative to assisted suicide in the UK.

🥉 Top 5% Journal

3 weeks ago • International journal of psychology : Journal international de psychologie

Link Between Natural Psychedelic Use and High Levels of Grandiose NarcissismRelationship Between Naturalistic Psychedelic Use and Grandiose Narcissism: An Online Cross-Sectional Study.

📖 Top 20% Journal

3 weeks ago • BMJ open

Safety and acceptability of two psilocybin doses in bipolar II depression: plan for an open-label feasibility studyAcceptability and safety of two sequential doses of psilocybin in bipolar II depression: protocol for an open-label single-arm feasibility study.

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3 weeks ago • Scientific reports

Changes in discrimination-related trauma symptoms after MDMA-assisted therapy for PTSDChanges in trauma symptoms of discrimination after MDMA-assisted psychotherapy for posttraumatic stress disorder.

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3 weeks ago • Translational psychiatry

Epigenetic effects on brain function of two new brain-changing drugs: ketamine and MDMABrain-targeted epigenetic effects of two emerging psychoplastogens: ketamine & MDMA.

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3 weeks ago • Molecular psychiatry

Molecular changes linked to long-lasting brain effects of classical psychedelics and ketamineEpigenetic landscapes of classical psychedelics and ketamine: molecular mechanisms of long-lasting neuromodulation.

🥈 Top 2% Journal

3 weeks ago • Pharmacology, biochemistry, and behavior

Psychedelics and the brain's relay and thinking systems: a broad reviewPsychedelics and the thalamocortical system: A scoping review.

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3 weeks ago • Therapeutic advances in psychopharmacology

Using MDMA-assisted therapy for borderline personality disorder and complex PTSD: a summary of existing studiesMaking a case for using MDMA-assisted psychotherapy for borderline personality disorder and complex PTSD: a descriptive systematic review of the literature.

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3 weeks ago • The International journal on drug policy

Canadians' knowledge and views on psychedelic drug stores, their rules, and public healthPsychedelics stores, their regulation and public health: knowledge, perceptions, attitudes and opinions of Canadians.

🎖️ Top 10% Journal

4 weeks ago • The International journal on drug policy

Why Addressing Negative Expectations Matters More Than Keeping Trials Blind in Psychedelic StudiesRedefining the real problem in psychedelic trials: Why fighting the Lessebo matters more than blinding integrity.

🎖️ Top 10% Journal

4 weeks ago • BMC medicine

Australian healthcare professionals’ views on using psilocybin to ease cancer-related existential distressThe need for another tool: Australian healthcare professionals on the use of psilocybin for existential distress in people with cancer.

🥉 Top 5% Journal

4 weeks ago • The British journal of psychiatry : the journal of mental science

Psilocybin therapy in adult women with anorexia nervosa: pilot studyPsilocybin therapy for adult females with anorexia nervosa: pilot study.

🥉 Top 5% Journal

1 month ago • Therapeutic advances in psychopharmacology

Ketamine changes brain signal patterns in major depression, which may relate to brain excitation-inhibition balance and help predict treatment responseKetamine alters the aperiodic EEG exponent in major depression: implications for cortical E/I balance and treatment prediction.

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1 month ago • The International journal on drug policy

Canada's changing policies and history of psychedelic use for end-of-life distressPolicy pathways and historical insights: Canada's evolving approach to psychedelic access for end-of-life distress.

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4 days ago • Metabolic engineering communications

Rebuilding the two-step process that bacteria use to make DMTReconstituting a two-step pathway for N,N-dimethyltryptamine (DMT) biosynthesis in bacteria.

📖 Top 20% JournalArticle

5 days ago • European journal of clinical pharmacology

Heart safety of psilocybin use in mental health treatment: a reviewCardiovascular safety of psilocybin in psychiatric practice: a narrative review.

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Psychedelic Science Research Papers