OpenScience.ink

3 weeks ago • Science China. Life sciences

Inflammation as a key factor in the development and treatment resistance of acute myeloid leukemiaInflammation as a central driver in AML pathogenesis and therapy resistance.

🥉 Top 5% JournalArticle

3 weeks ago • Pharmacological research

Camellioside A may activate cell cleanup pathways to reduce UVB-related skin agingCamellioside A engages SIRT3 to promote FOXO3-PINK1/parkin dependent mitophagy and attenuate UVB-induced skin photoaging.

🥉 Top 5% JournalArticle

3 weeks ago • Drug design, development and therapy

Chinese Herbal Medicine for Insomnia: From Laboratory Findings to Clinical UseFrom Mechanistic Evidence to Clinical Translation: A Narrative Review of Chinese Herbal Medicine for Insomnia.

📖 Top 20% JournalArticle

3 weeks ago • Experimental eye research

Naringin reduces eye surface inflammation in dry eye disease by boosting cell cleaning and lowering oxidative stress through the PI3K/AKT/mTOR pathwayNaringin alleviates ocular surface inflammation in dry eye disease by enhancing autophagic flux and mitigating oxidative stress through downregulation of the PI3K/AKT/mTOR pathway.

📖 Top 20% JournalArticle

3 weeks ago • Advances in biological regulation

Differences and roles of two main systems that clear damaged cell powerhousesBNIP3/NIX-mediated mitophagy versus Parkin-mediated mitophagy: mechanistic differences and functional implications.

📖 Top 20% JournalArticle

3 weeks ago • Autophagy reports

TRPML3 and TRPML1/3 differently control unusual MIF release through TMED10 and secretory autophagyTRPML3 and TRPML1/3 differentially regulate unconventional MIF secretion through TMED10 and secretory autophagy.

Article

3 weeks ago • Expert opinion on drug delivery

Using Tiny Particles to Restore Cell Cleanup in Brain DegenerationNanotechnology meets neurodegeneration: restoring lysosomal function with nanovectors.

Article

3 weeks ago • Ageing research reviews

How Changes in Cellular Energy Signals Connect Aging Signs to Chronic InflammationTHE AGING PURINOME: A PURINERGIC FRAMEWORK LINKING THE HALLMARKS OF AGING TO INFLAMMAGING.

🥈 Top 2% JournalArticle

3 weeks ago • Mechanobiology in medicine

Using Joint Tissue Mechanics in Osteoarthritis to Develop Better Material-Based TreatmentsTranslating mechanobiology in osteoarthritis to biomaterial-informed therapeutic strategies.

📖 Top 50% JournalArticle

3 weeks ago • Journal of advanced research

Hyodeoxycholic acid may help bone stem cells fight aging and abnormal fat buildup in postmenopausal osteoporosis through a specific cell cleanup pathwayHyodeoxycholic acid rejuvenates BMSCs against postmenopausal osteoporosis by attenuating senescence and aberrant adipogenesis via TGR5-ESR1-mediated mitophagy.

🥉 Top 5% JournalArticle

3 weeks ago • Cytokine

Strength training reduces liver inflammation and boosts energy cell changes in mice lacking IL-10Strength training attenuates hepatic inflammation and potentiates mitochondrial adaptations in IL-10-deficient mice.

Article

3 weeks ago • Aging and disease

Mitochondria’s usual and unusual roles in stroke and agingMitochondria Beyond Bioenergetics: Canonical and Non-Canonical Functions in Ischemic Stroke and Aging.

🥉 Top 5% JournalArticle

3 weeks ago • GeroScience

Mitochondria problems and chronic inflammation: a link between energy failure and aging cellsMitochondrial dysfunction and inflammaging: a mechanistic bridge between bioenergetic failure and senescence.

🎖️ Top 10% JournalArticle

3 weeks ago • Diabetes, obesity & metabolism

Cell Recycling Controls Foxo1 Protein Levels to Regulate Liver Glucose Production in Response to GlucagonAutophagy Regulates Foxo1 Protein Abundance to Control Hepatic Glucose Production in Glucagon Signalling.

Article

3 weeks ago • Biosensors & bioelectronics

Metabolic chemical patterns predict aging and muscle cell development in immature muscle cellsElectrochemical metabolic profiling predicts senescence and myogenic fate in undifferentiated myoblasts.

🥉 Top 5% JournalArticle

3 weeks ago • Autophagy

Real-time imaging of cell cleaning processes in mice using advanced two-photon microscopyLive visualization of dynamic autophagy processes in LC3 reporter mice using enhanced two-photon microscopy.

🥈 Top 2% JournalArticle

3 weeks ago • Environmental health perspectives

Links Between Green Space, Air Pollution, and Different Patterns of Biological AgingAssociations of Green Space and Air Pollution Mixture with Heterogeneous Biological Aging Patterns.

🥉 Top 5% JournalArticle

3 weeks ago • Aging

Small cell-released particles may carry aging signals to nearby cells in lab modelsSmall extracellular vesicles as mediators of paracrine senescence in cellular models of aging.

📖 Top 20% JournalArticle

3 weeks ago • Experimental neurology

Drugs that affect NAD+ metabolism protect nerve fibers inside and outside the brain in a lab model of nerve injuryCombined pharmacological targeting of NAD+ metabolism preserves central and peripheral axons in an ex vivo model of Wallerian degeneration.

🎖️ Top 10% JournalArticle

3 weeks ago • Human reproduction update

Understanding how the immune system controls ovarian aging and possible treatmentsDecoding the immune regulation of ovarian aging: mechanisms and therapeutic strategies.

🥇 Top 1% JournalArticle

3 weeks ago • Autophagy

How TBK1 adds phosphate to WIPI2 to connect bacteria detection with autophagosome formation in cell cleaningTBK1-mediated phosphorylation of WIPI2 links bacteria recognition to autophagosome formation in xenophagy.

🥈 Top 2% JournalArticle

3 weeks ago • Advanced science (Weinheim, Baden-Wurttemberg, Germany)

🥈 Top 2% JournalArticle

3 weeks ago • The Journal of physiology

Differences in Mitochondrial Changes and Repair in Two Mouse Models of Friedreich's AtaxiaMitochondrial dynamics and repair differences in two mouse models of Friedreich's ataxia.

🎖️ Top 10% JournalArticle

3 weeks ago • Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Bacteria-Produced 1-Allylpiperazine May Reduce Parkinson’s Symptoms by Boosting Cellular CleanupBacteria-Derived 1-Allylpiperazine Alleviates Symptoms of Parkinson's Disease Model by Promoting Autophagy.

🥈 Top 2% JournalArticle

3 weeks ago • Journal of Huntington's disease

Ways to Help Break Down Mutant Huntingtin Protein and Potential TreatmentsDirecting mutant huntingtin towards degradation: Strategies and therapeutic opportunities.

🎖️ Top 10% JournalArticle

3 weeks ago • Ecotoxicology and environmental safety

Sodium arsenite speeds up aging in C. elegans parents and offspring through insulin signaling, oxidative stress, and cell cleanup processesSodium arsenite accelerates aging of Caenorhabditis elegans parents and offspring through the insulin signaling pathway, oxidative stress, and autophagy.

🎖️ Top 10% JournalArticle

3 weeks ago • Phytotherapy research : PTR

Astragaloside IV may protect kidney filtering cells in diabetic kidney disease by restoring cell recycling and preventing cell death through blocking Notch1 signaling via SIRT6 activityAstragaloside IV Restores Autophagy and Inhibits Apoptosis for Podocyte Protection in Diabetic Nephropathy by Inhibiting Notch1 Signaling via SIRT6-Mediated Deacetylation.

Article

3 weeks ago • Trends in biochemical sciences

Metabolic enzymes acting as protein switches that add or remove phosphate groupsMetabolic enzymes moonlighting as protein kinases and phosphatases.

🥈 Top 2% JournalArticle

3 weeks ago • GeroScience

Brain health score linked to eye structure and metabolism in UK Biobank dataBrain care score and retinal health: structural and metabolic insights from the UK Biobank.

🎖️ Top 10% JournalArticle

3 weeks ago • Neurochemical research

Repeated Sleep Loss with Aging May Cause Early Memory Problems, Brain Inflammation, and Blood-Brain Barrier Issues in Female RatsRecurrent Sleep Restriction During Aging Induces Early Recognition Memory Impairment, Neuroinflammation, and Blood-Brain Barrier Dysfunction in Female Wistar Rats.

📖 Top 20% JournalArticle

← prevpage 13 of 16next →

Latest Longevity & Aging Research Papers