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1 week ago • Gerontology

Links Between Oxidative Balance and Biological Aging, and Possible Roles of Inflammation and Cholesterol Ratios in US AdultsAssociation of the Oxidative Balance Score with GOLD BioAge: Potential Mediating Roles of SIRI and UHR among US Adults.

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1 week ago • iScience

Stathmin 1 controls mitochondrial cleanup and non-dividing functions in blood stem and early cellsStathmin 1 regulates mitophagy and non-proliferative cellular function in hematopoietic stem and progenitor cells.

🎖️ Top 10% JournalArticle

1 week ago • European journal of pharmacology

Understanding the Two Roles of NADPH Oxidase 4 in Heart Scarring to Guide Targeted TreatmentsResolving the dual nature of NADPH oxidase 4 in cardiac fibrosis for selective therapeutic targeting: A narrative review.

📖 Top 20% JournalArticle

1 week ago • Journal of visualized experiments : JoVE

Ways to Measure How Caenorhabditis elegans Resist Different Types of StressMethods for Measuring Resistance to Multiple Stressors in Caenorhabditis elegans.

📖 Top 50% JournalVideo-Audio Media

1 week ago • Basic and clinical andrology

How energy cell damage and inflammation may contribute to infertility caused by varicoceleThe role of the mitochondrial injury-mediated oxidative stress-sterile inflammation axis in varicocele-induced infertility: a narrative review.

📖 Top 30% JournalArticle

1 week ago • Ageing research reviews

Brain cell loss in Sub-Saharan Africa linked to aging, genetic differences, and lifelong environmental exposuresNeurodegeneration in sub-Saharan Africa: Intersections of biological ageing, genomic diversity and the lifetime exposome.

🥈 Top 2% JournalArticle

1 week ago • JCI insight

The cell recycling receptor TEX264 helps skin cells mature and is disrupted in Darier diseaseThe endoplasmic reticulum autophagy receptor TEX264 drives epidermal differentiation and is dysregulated in Darier disease.

🥉 Top 5% JournalArticle

1 week ago • Progress in neuro-psychopharmacology & biological psychiatry

Cell aging in normal ageing and brain diseases: causes, signs, and possible treatmentsCellular senescence in ageing and neurodegenerative disorders: Molecular mechanisms, biomarkers, and therapeutic strategies.

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1 week ago • Kidney360

Cell Aging as a Key Link between Chronic Kidney Disease, Heart Scarring, and AgingCellular Senescence as a Core Mechanistic Link between CKD, Cardiac Fibrosis, and Aging.

📖 Top 20% JournalArticle

1 week ago • Journal of medicinal chemistry

Krüppel-like Factors as Timed Regulators of Cell Recycling That Influence Cell Survival and DiseaseKrüppel-like Factors in Autophagy: A Spatiotemporal Rheostat Framework Linking Cellular Fate and Disease.

🎖️ Top 10% JournalArticle

1 week ago • Ageing research reviews

Understanding Aging Cells in Heart Failure: Key Processes and Potential TreatmentsMapping cellular senescence in heart failure: knowledge evolution, mechanistic modules, and senotherapeutic opportunities.

🥈 Top 2% JournalArticle

1 week ago • Inflammation and regeneration

Microglia Energy Problems as a New View of Depression CausesMitochondrial dysfunction in microglia: a novel perspective of depression pathogenesis.

🎖️ Top 10% JournalArticle

1 week ago • Autophagy

Reducing SSH1 boosts cell cleanup by attracting ATG9A and helps break down tau proteinSSH1 knockdown increases autophagosome formation through ATG9A recruitment and promotes tau protein degradation.

🥈 Top 2% JournalArticle

1 week ago • Cell metabolism

How bone sensing of movement slows aging and may extend lifespanDynamic force sensing by bone delays aging and extends lifespan.

🥇 Top 1% JournalArticle

1 week ago • Clinical science (London, England : 1979)

The AIM2 immune sensor is linked to age-related heart problems after blood flow returns in miceThe AIM2 inflammasome drives age-dependent cardiac dysfunction following ischemia-reperfusion in mice.

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1 week ago • Ecotoxicology and environmental safety

Long-term exposure to the tire chemical 6-PPDQ may cause aging signs and movement and behavior problems through ABL1-p53-autophagy signalingChronic exposure to the tire-wear contaminant 6-PPDQ induces senescence-associated biomarkers and neurobehavioral deficits: Involvement of ABL1-p53-autophagy signaling.

🎖️ Top 10% JournalArticle

1 week ago • The Journal of nutritional biochemistry

Selenium reduces cadmium-caused ovary scarring by preventing aging of immune cells in chickensSelenium alleviates cadmium-induced ovarian fibrosis by inhibiting macrophage senescence in chickens.

📖 Top 20% JournalArticle

1 week ago • Redox biology

Reducing harmful molecules in joint tissue may lower cell death and slow osteoarthritisModulating the synovial ROS-NO-RNS network attenuates fibroblast-like synoviocyte pyroptosis and osteoarthritis progression.

🥈 Top 2% JournalArticle

1 week ago • Materials today. Bio

Nature-inspired tiny cages that target damaged kidneys for combined diagnosis and treatment of sudden blood flow injuryBiomimetic nanocages with cascade homing for theranostics of ischemia-reperfusion acute kidney injury.

🥉 Top 5% JournalArticle

1 week ago • Biogerontology

Resveratroloside reduces aging signs in cells by improving energy production and DNA organizationResveratroloside alleviates senescence-associated phenotypes in vitro through the coordinated regulation of mitochondrial function and chromatin structure.

📖 Top 20% JournalArticle

1 week ago • Pulmonary pharmacology & therapeutics

Cell Aging and Blood Vessel Aging in Lung High Blood Pressure: Molecular Causes, Treatments, and Clinical MeasuresCellular senescence and vascular ageing in pulmonary hypertension: Molecular mechanisms, therapeutic strategies, and translational endpoints.

📖 Top 30% JournalArticle

1 week ago • GeroScience

What dog lifespan treatments can teach us about human healthLessons from dog lifespan therapeutics for their human companions.

🎖️ Top 10% JournalArticle

1 week ago • Food research international (Ottawa, Ont.)

Better long-term growth and muscle development of cow muscle stem cells by editing the CDKN2A geneImproved long-term proliferation and myogenic differentiation of bovine muscle stem cells through CDKN2A gene editing.

🎖️ Top 10% JournalArticle

1 week ago • Cardiorenal medicine

The apelin signaling system as an additional target alongside RAAS blockers in heart and kidney diseaseThe apelin/APJ system as a complementary target to RAAS blockade in cardiorenal disease.

📖 Top 30% JournalArticle

1 week ago • Ageing research reviews

Selective Removal of Cell Stress Structures by Receptors in Brain Diseases: How It Works and Possible TreatmentsReceptor-Specific ER-Phagy in Neurodegenerative Diseases: Molecular Mechanisms and Emerging Therapeutic Opportunities.

🥈 Top 2% JournalArticle

1 week ago • Brain pathology (Zurich, Switzerland)

Galectin-3 may protect against prion disease by helping brain immune cells clear harmful proteinsProtective role of Galectin-3 in prion disease through regulation of microglial PrPSc uptake.

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1 week ago • Molecular biomedicine

How sirtuin proteins work and their potential for treatmentsThe sirtuin family: from mechanisms to therapy.

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1 week ago • Experimental gerontology

Blood from people after fermented whey protein intake may boost muscle cell growth and protein productionHuman serum collected after fermented whey protein supplementation stimulates myocellular growth and protein synthesis: A randomized, double-blind, active-controlled crossover trial.

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1 week ago • Neuroscience letters

Zinc may trigger cell cleaning by controlling a key protein after brain blood flow injuryZinc activates autophagy by regulating HDAC6 expression following cerebral ischemia/reperfusion injury.

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1 week ago • Trends in endocrinology and metabolism: TEM

How the recovery period after childbirth may influence aging in mothersThe postpartum recovery window as a determinant of maternal aging.

🥈 Top 2% JournalArticle

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