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1 week ago • Traffic (Copenhagen, Denmark)

Tau Protein Clumps in Lysosomes Disrupt Cell Cleanup in Neurodegeneration"S-Tau-Lled" Lysosomes Disrupt Autophagic Processes in Neurodegeneration.

📖 Top 20% JournalArticle

1 week ago • Pediatric research

How Early-Life Factors May Cause Lasting Lung Changes in Bronchopulmonary Dysplasia Through Epigenetic ProgrammingEpigenetic programming in bronchopulmonary dysplasia: a framework linking early-life exposures to persistent lung disease-a narrative review.

📖 Top 20% JournalArticle

1 week ago • Materials today. Bio

Nanoparticles carrying Panax notoginseng polysaccharides reduce Alzheimer's symptoms by changing immune cell metabolism through energy and oxygen sensing pathwaysMicroglia-targeted Panax notoginseng polysaccharide nanoparticles alleviate Alzheimer's disease via AMPK-mTOR/HIF-1α-mediated immunometabolic reprogramming.

🥉 Top 5% JournalArticle

1 week ago • Talanta

A fluorescent probe that shows mitochondrial nitric oxide and pH changes during cell self-cleaningA mitochondria-targeted ratiometric fluorescent probe for visualizing NO generation coupled with mitochondrial pH variations during autophagy.

📖 Top 20% JournalArticle

1 week ago • GeroScience

Infection patterns over time linked to faster biological aging in adultsLongitudinal infection trajectories and biological aging acceleration in adults: a prospective cohort study.

🎖️ Top 10% JournalArticle

1 week ago • Aging medicine (Milton (N.S.W))

Understanding How Biological Aging Works to Help Medical ResearchInsights Into the Mechanisms of Biological Aging That Guide Translational and Clinical Research.

📖 Top 30% JournalEditorial

1 week ago • International archives of occupational and environmental health

Shift work linked to faster aging and higher death risk in US adultsShift work, accelerated biological aging and mortality risk in US adults: a national prospective cohort study.

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2 weeks ago • Biomaterials

Vitamin E-NAD+ nanoparticle treatment for osteoarthritis by reducing inflammation and oxidative stressBioactive vitamin E-NAD+ conjugate nanoparticles for osteoarthritis management via simultaneous suppression of inflammation and oxidative stress.

🥉 Top 5% JournalArticle

2 weeks ago • Science China. Life sciences

Single-cell analysis reveals changes in gene variants and immune cells during human agingSingle-cell multi-omics dissects transcript isoform and immune repertoire dynamics in human immunosenescence.

🥉 Top 5% JournalArticle

2 weeks ago • Journal of cellular and molecular medicine

Gene-Modified Stem Cell Vesicles May Help Insulin Resistance by Improving Mitochondrial Communication and microRNA ControlTherapeutic Potential of Gene Modified MSC-Exos in Insulin Resistance: Mitochondrial Crosstalk and miRNA Regulation.

📖 Top 20% JournalResearch Support, Non-U.S. Gov't

2 weeks ago • Annals of hepatology

Role of CD38 in Liver Disease: How It Works, Links to Illness, and Treatment PossibilitiesCD38 in hepatic pathobiology: mechanisms, disease association and therapeutic implications.

📖 Top 20% JournalArticle

2 weeks ago • Ageing research reviews

Contacts Between Cell Energy and Protein Factories May Influence Aging of Brain Immune Cells in Alzheimer's DiseaseMitochondria-endoplasmic reticulum contact sites (MERCS/MAM): Multi-layered upstream regulators of microglial senescence in Alzheimer's disease.

🥈 Top 2% JournalArticle

2 weeks ago • Free radical biology & medicine

Misfolding of a key enzyme disrupts energy production and balance in mitochondriaMisfolding of cystathionine beta-synthase impairs mitochondrial homeostasis and cellular bioenergetics.

🥉 Top 5% JournalArticle

2 weeks ago • Ageing research reviews

Using Biomaterials to Help Older Bones Heal and Stop the Cycle of AgingBreaking the Self-Reinforcing Cycle of Aging: Biomaterial Strategies for Aged Bone Regeneration.

🥈 Top 2% JournalArticle

2 weeks ago • Molecular neurobiology

Isorhapontigenin may protect the brain from inflammation-related damage by affecting immune response pathwaysNeuroprotective Effect of Isorhapontigenin (ISO) Against LPS-Induced Neurodegenerative Condition via TLR4/RAGE-Mediated p-NF-kB Activation.

🎖️ Top 10% JournalArticle

2 weeks ago • Biochimica et biophysica acta. Molecular basis of disease

How Circular RNAs and SIRT1 Control Gene Activity After Transcription and Their Links to Human DiseaseCircular RNAs and SIRT1 in post-transcriptional regulation and human disease.

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2 weeks ago • Science advances

Step-by-step process of bringing ULK1 protein to membranes during cell cleanupReconstitution of multistep recruitment of ULK1 to membranes in autophagy.

🥈 Top 2% JournalArticle

2 weeks ago • ACS applied materials & interfaces

Repeated Pressure Shows Age-Related Inflammation in Human Stem Cell ClustersDynamic Compression Reveals Donor-Age-Associated Inflammaging in Human Mesenchymal Stromal Cell Spheroids.

🎖️ Top 10% JournalArticle

2 weeks ago • Ageing research reviews

Oxidation Changes in SOD1 Protein and Their Role in Skin Aging: What We Know and What Needs More StudyPosttranslational Oxidation of SOD1 and Skin Aging: Evidence, Gaps, and Future Directions.

🥈 Top 2% JournalArticle

2 weeks ago • Nature reviews. Neurology

The role of the complement immune system and related treatments in brain diseasesRole of complement and complement-targeted therapeutics in neurological diseases.

🥇 Top 1% JournalArticle

2 weeks ago • International journal of molecular medicine

How Cell Recycling Controls Immune Cell Survival by Managing Metabolism and a Combined Cell Death ProcessAutophagy determines the fate of immune cells by regulating metabolic remodeling and PANoptosis (Review).

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2 weeks ago • International journal of molecular medicine

Cell Death in Metabolic Syndrome: From How It Happens to Possible TreatmentsProgrammed cell death in metabolic syndrome: From molecular mechanisms to therapeutic strategies (Review).

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2 weeks ago • Journal of ethnopharmacology

Lactiflorin may help stop a damaging cycle of cell cleanup and stress in Alzheimer's by activating key cell repair signalsBreaking the autophagy-oxidative stress vicious cycle in Alzheimer's disease: Lactiflorin unlocks P62 dual phosphorylation via ULK1 targeting.

📖 Top 20% JournalArticle

2 weeks ago • Ageing research reviews

Understanding and Treating Alzheimer's by Focusing on Mitochondria FunctionTargeting the mitochondrial functional network: Decoding upstream pathological mechanisms and novel therapeutic paradigms for Alzheimer's disease.

🥈 Top 2% JournalArticle

2 weeks ago • Rheumatology (Oxford, England)

🎖️ Top 10% JournalArticle

2 weeks ago • Gut microbes

How Nutrition Affects Communication Between the Gut and Brain Immune System Throughout LifeNutritional regulation of gut-brain immune crosstalk across the lifespan.

🥈 Top 2% JournalArticle

2 weeks ago • Arthritis & rheumatology (Hoboken, N.J.)

CASTOR1 controls immune responses in the blood and may contribute to lupus developmentCASTOR1 regulates humoral immune responses and contributes to the pathogenesis of systemic lupus erythematosus.

🥈 Top 2% JournalArticle

2 weeks ago • JOR spine

Understanding the Role of Oxygen-Sensing Proteins in Spinal DiscsMy Love Story With HIFs in the Disc: A Journey to the Humboldt Research Award.

📖 Top 20% JournalArticle

2 weeks ago • Journal of visualized experiments : JoVE

Bone Growth Effects, Unknown Mechanisms, and Safety of Nano-Pearl Powder and Water-Soluble Nacre ComponentsNano-Pearl Powder and Nacre-Derived Water-Soluble Matrix in Osteogenesis: Evidence, Mechanistic Gaps, and Safety Considerations.

📖 Top 50% JournalVideo-Audio Media

2 weeks ago • Journal of the National Cancer Institute

Psychological distress in adults with colorectal cancer linked to biological age and neighborhood disadvantagePsychological distress in adult patients with colorectal cancer: roles of biological age and neighborhood deprivation.

🥇 Top 1% JournalArticle

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