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2 weeks ago • Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Blocking COMPASS Promoter Activation Makes HDAC-Inhibited Gastric Cancer Keep Genes Turned Off During RecoveryDisabling COMPASS Promoter Licensing Shifts HDAC-Inhibited Gastric Cancer Toward Sustained Transcriptional Suppression During Recovery.

🥈 Top 2% JournalArticle

2 weeks ago • International journal of molecular sciences

Using Genetic and Molecular Methods to Enhance Pest Control Abilities of Insect-Killing NematodesAdvanced Genetic and Molecular Techniques for Improving Biocontrol Traits of Entomopathogenic Nematodes.

📖 Top 20% JournalArticle

2 weeks ago • International journal of molecular sciences

Comparing Prime Editing and CRISPR Methods to Fix the CFTR-F508del Mutation in Patient-Derived Airway Stem CellsComparison of Prime Editing and CRISPR-Cas Mediated HDR in Correcting CFTR-F508del Mutation in Patient iPSC-Derived Airway Basal Cells.

📖 Top 20% JournalComparative Study

2 weeks ago • ACS applied materials & interfaces

Testing many lipid nanoparticles to find the best ones for delivering CRISPR gene-editing toolsHigh-Throughput Screening of a Lipid Nanoparticle (LNP) Library Identifies Lead Formulations for CRISPR-Cas9 Ribonucleoprotein Delivery and Gene Editing.

🎖️ Top 10% JournalArticle

2 weeks ago • Human mutation

Fast and Accurate Detection of USP26 Gene Variants Using CRISPR TechnologyRapid and Sensitive Detection of USP26 Cluster Variants Based on CRISPR/Cas12a.

🎖️ Top 10% JournalArticle

2 weeks ago • Methods in molecular biology (Clifton, N.J.)

Using CRISPR to Change Genes and Gene Activity in Ewing SarcomaGenetic and Epigenetic Manipulation Using CRISPR Techniques in Ewing Sarcoma.

📖 Top 50% JournalArticle

2 weeks ago • Analytical methods : advancing methods and applications

Highly sensitive detection of Staphylococcus aureus using a programmable DNA sensor and CRISPR amplificationA programmable aptamer-triggered B-PER/CRISPR cascade amplification platform for ultrasensitive detection of Staphylococcus aureus.

📖 Top 50% JournalArticle

2 weeks ago • Current atherosclerosis reports

Single-dose gene-editing therapies targeting PCSK9 in living organismsIn-vivo CRISPR/Base-Editing "One-Shot" Therapies Targeting PCSK9.

🎖️ Top 10% JournalArticle

2 weeks ago • Hemoglobin

Personalized Treatments for Sickle Cell Disease: From Biological Processes to Potential CuresPrecision Medicine in Sickle Cell Disease: From Molecular Pathways to Curative Strategies.

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2 weeks ago • Plant cell reports

Restoring function to a broken SlGLK2 gene in tomato using precise genome editingReactivation of a loss-of-function SlGLK2 allele by frame-restoring genome editing in tomato.

🎖️ Top 10% JournalArticle

2 weeks ago • Human gene therapy

Using Mobile DNA and CRISPR-Based Tools Beyond Viruses for Genome EditingBeyond Viruses: Transposons and CRISPR-Programmable Nonviral Systems for Genome Engineering.

📖 Top 20% JournalArticle

2 weeks ago • Biosensors & bioelectronics

RNA-controlled CRISPR test for detecting tuberculosis and rifampicin drug resistance at the same timeUnified hybrid RNA-regulated CRISPR diagnostic for concurrent Mycobacterium tuberculosis detection and rifampicin resistance profiling.

🥉 Top 5% JournalArticle

2 weeks ago • Biotechnology advances

Development and uses of plant base editors from basic to advanced toolsFrom base transitions to expanded editing tools: development and applications of plant base editors.

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2 weeks ago • Frontiers in microbiology

Portable Tuberculosis Test Using a Paper Card and CRISPR Technology with Simple DNA AmplificationAn FTA card-based CRISPR/Cas12a platform with isothermal amplification for portable tuberculosis diagnosis.

📖 Top 20% JournalArticle

2 weeks ago • Frontiers in microbiology

Rapid visual test using omp25 and CRISPR technology to detect Brucella DNA linked to brucellosisDevelopment and preliminary validation of an omp25-based RPA-CRISPR/Cas12a visual assay for rapid screening of brucellosis-associated Brucella DNA.

📖 Top 20% JournalArticle

3 weeks ago • Cellular & molecular immunology

Activating an alternative NF-κB pathway to improve cancer-killing by engineered T cellsCRISPRa screen unveils noncanonical NF-κB to boost the antitumor activity of TCR-based CAR-T cells.

🥇 Top 1% JournalArticle

3 weeks ago • Cancer research

A mouse brain tumor model mimics key molecular, immune, and functional traits of human glioblastoma to support treatment researchA syngeneic murine glioma model recapitulates key molecular, immunologic, and functional features of human glioblastoma to enable therapeutic development.

🥈 Top 2% JournalArticle

3 weeks ago • Transgenic research

CRISPR gene editing in food and feed crops: patent issues, worldwide access, and views from IndiaCRISPR genome editing in food and feed crops: intellectual property challenges, global accessibility, and the Indian perspective.

📖 Top 50% JournalArticle

3 weeks ago • Neuron

A gene delivery system for studying immune cells in the brain across different speciesA cross-species AAV platform for precise microglial interrogation.

Article

3 weeks ago • Renal failure

Genes that affect kidney filter cell survival under oxidative stress, found by genome-wide CRISPR screensGenome-wide CRISPR screens identify shared and context-specific regulators of podocyte resistance to oxidative injury.

📖 Top 30% JournalArticle

3 weeks ago • Journal of immunology (Baltimore, Md. : 1950)

CRISPR-Cas9 screen finds eIF4G2 controls CD8+ T cell dysfunctionCRISPR-Cas9 screen identifies eIF4G2 as a regulator of CD8+ T cell dysfunction.

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3 weeks ago • Zoological research

Improved gGBE tool allows reliable G-to-Y DNA changes in mammal cells and zebrafish embryosOptimized gGBE enables robust G-to-Y conversion in mammalian cells and zebrafish embryos.

📖 Top 20% JournalArticle

3 weeks ago • Frontiers in plant science

New developments in improving plant metabolism using synthetic biologyAdvances in plant metabolic engineering through synthetic biology.

📖 Top 20% JournalArticle

3 weeks ago • Ear and hearing

New Gene Editing Treatments for Inherited DeafnessEmerging Therapies for Genetic Deafness: The Rise of Precision Gene Editing.

📖 Top 20% JournalArticle

3 weeks ago • Nature communications

Gene editing reveals two roles of DNMT3A in helping tumors avoid the immune systemIn vivo CRISPR screens identify dual functions of DNMT3A in mediating tumor immune evasion.

🥈 Top 2% JournalResearch Support, Non-U.S. Gov't

3 weeks ago • Plant cell reports

mTREX2 increases large DNA deletions during CRISPR editing of complex sugarcane genomemTREX2 co-expression promotes large deletions in CRISPR/Cas12a editing of the highly polyploid sugarcane genome.

🎖️ Top 10% JournalArticle

3 weeks ago • Cureus

CRISPR Genome Editing for Inherited Heart Diseases: New Treatments, Emerging Techniques, and Challenges for Medical UseClustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-Based Genome Editing in Inherited Cardiovascular Diseases: Therapeutic Advances, Emerging Editing Platforms, and Translational Challenges.

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3 weeks ago • Physical activity and nutrition

Combining gene editing and exercise to improve function in ALSIntegrative ALS therapy: gene targeted therapy by base editing and potential exercise rehabilitation as synergistic strategies for functional recovery.

📖 Top 50% JournalArticle

3 weeks ago • MicrobiologyOpen

Combining two DNA techniques for highly sensitive detection of Mycoplasma bovisSynergistic Integration of Recombinase Polymerase Amplification and CRISPR-Cas12a Enables High-Sensitivity Detection of Mycoplasma bovis.

📖 Top 20% JournalArticle

3 weeks ago • Neurobiology of disease

A KIF1A gene change may disrupt nerve cell development and transport by altering key growth and signaling pathwaysKIF1A c.773C > T impairs neural progenitor differentiation and axonal transport in association with dysregulated Wnt/β-catenin-BDNF signaling.

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