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2 weeks ago • Advanced materials (Deerfield Beach, Fla.)

Positively Charged Lipid Nanoparticles Carry Platinum-Based Nanocages for Cancer Treatment in Living OrganismsCharge-Reversed Lipid Nanoparticles Enable Encapsulation of Pt2L4 Nanocages for In vivo Anti-Cancer Treatment.

🥇 Top 1% JournalArticle

2 weeks ago • Biomaterials research

Nasal delivery of Netrin-1 mRNA in tiny vesicles may reduce brain cell death after strokeIntranasal Netrin-1 modRNA-Loaded Extracellular Vesicles Reduce Neuronal Apoptosis after Ischemic Stroke.

Article

2 weeks ago • Angewandte Chemie (International ed. in English)

Lipid Nanoparticles Using Molecular Recognition Boost Cancer Immunotherapy by Changing the Tumor EnvironmentSupramolecular Pretargeting Lipid Nanoparticles Based on Host-Guest Recognition Potentiate Cancer Immunotherapy by Reprogramming Tumor Microenvironment.

🥇 Top 1% JournalArticle

2 weeks ago • Journal for immunotherapy of cancer

IL7R mRNA treatment boosts cancer-fighting T cells and slows tumor growth in animal modelsIL7R mRNA therapy enhances antitumor T cell immunity and suppresses tumor growth in preclinical tumor models.

🥈 Top 2% JournalArticle

2 weeks ago • International journal of nanomedicine

Using DNA Barcodes to Find Lipid Nanoparticles That Deliver TRAIL-mRNA to Lungs to Kill Tumor Cells in a Metastasis ModelHigh-Throughput DNA Barcoding Identifies Lipid Nanoparticles for Lung Delivery of TRAIL-mRNA to Induce Tumor Cell Death in Experimental Metastasis Model.

🎖️ Top 10% JournalArticle

2 weeks ago • Bioengineering & translational medicine

HER2-targeted mRNA vaccine combined with radiation slows lung tumor growth in mice and how it worksCombined HER2-targeted mRNA-LNP vaccine and radiotherapy suppress Lewis lung carcinoma growth in mice: Efficacy and mechanistic insights.

🎖️ Top 10% JournalArticle

2 weeks ago • Journal of controlled release : official journal of the Controlled Release Society

How sugar-coated cell surfaces and protein layers affect mRNA carrier uptake in different cell typesThe role of glycocalyx-protein corona interactions in the cell type-specific uptake of mRNA nanocarriers.

Article

2 weeks ago • Molecular therapy. Nucleic acids

Segmented mRNA tail regions with microRNA sites allow tissue-specific control for mRNA therapiesSegmented poly(A) tails with microRNA target sites confer tissue-specific regulation for mRNA therapeutics.

🥉 Top 5% JournalArticle

2 weeks ago • ACS applied bio materials

Fluorescent lipid nanoparticles designed to target two sites for improved small activating RNA deliveryReactive Polymer-Engineered Dual-Targeting Fluorescent Lipid Nanoparticles for Enhanced saRNA Delivery.

📖 Top 20% JournalArticle

2 weeks ago • International journal of nanomedicine

Challenges in Nanoparticle Delivery for Immune Cell Engineering: From Cell Uptake to Escaping Internal CompartmentsThe Nanoparticle Delivery Gap in Immune Cell Engineering: From Uptake to Endosomal Escape.

🎖️ Top 10% JournalArticle

2 weeks ago • Journal of controlled release : official journal of the Controlled Release Society

Lung surfactants in lipid nanoparticles for delivering mRNA to the lungsLung surfactants as a component of lipid nanoparticles for pulmonary mRNA delivery.

Article

2 weeks ago • Preparative biochemistry & biotechnology

Improving plasmid DNA recovery using membrane chromatography with added chemicalsAn additive-enhanced membrane chromatography approach for improved plasmid DNA recovery.

📖 Top 50% JournalArticle

2 weeks ago • ACS applied bio materials

C-5 Induction Boosts Uracil-Based Lipid Nanoparticles to Improve Redox-Driven Treatment in Liver CancerCorrelating the C-5 Induction Effect on Uracil-Based Nucleoside Lipid Nanoparticles for Enhanced Redox-Mediated Therapeutic Efficacy in Hepatocellular Carcinoma.

📖 Top 20% JournalArticle

2 weeks ago • Small (Weinheim an der Bergstrasse, Germany)

Fast and Efficient Capture of Engineered Cell Particles Carrying Functional Proteins Using Internal Twin-Strep TagsRapid and Efficient Affinity Isolation of Engineered Extracellular Vesicles Encapsulating Functional Proteins via Internal Twin-Strep Tetraspanin Tagging.

🥈 Top 2% JournalArticle

2 weeks ago • Biological & pharmaceutical bulletin

Using Fat-Based Nanoparticles to Disrupt Blood Vessels in Lung Cancer SpreadLipid Nanoparticle-Mediated Vascular-Disrupting Therapy for Lung Metastasis.

Article

2 weeks ago • Angewandte Chemie (International ed. in English)

A Specific tRNA Modification Helps RNA Bind to LipidsThe tRNA-Modification Geranyl-2-Thiouridine Enables RNA-Lipid Association.

🥇 Top 1% JournalArticle

3 weeks ago • Biomaterials

Designing tiny cell particles to deliver multiple treatments for silicosis and similar scarring lung diseasesEngineering extracellular vesicles for multi-cargo co-delivery in silicosis and related fibrotic diseases: design strategies and translational prospects.

🥉 Top 5% JournalArticle

3 weeks ago • Nanomedicine : nanotechnology, biology, and medicine

Liver delivery of FXR mRNA using lipid nanoparticles improves low-dose FXR drug treatment for MASLDHepatic delivery of FXR mRNA via lipid nanoparticles enhances the efficacy of a low-dose FXR agonist in the treatment of MASLD.

📖 Top 20% JournalArticle

3 weeks ago • Frontiers in immunology

Using AI to design a COVID-19 spike protein that may protect against many related coronavirusesAI-guided epitope engineering of a SARS-CoV-2 spike antigen for broad sarbecovirus neutralization.

🥉 Top 5% JournalArticle

3 weeks ago • International journal of pharmaceutics

Designing smart lipid nanoparticles for breast cancer using AI and personalized medicine to improve safety and effectivenessEngineering smart polymeric lipid nanoparticles for breast cancer: The convergence of AI and medical personalization to enhance efficacy and safety.

📖 Top 20% JournalArticle

3 weeks ago • Journal of controlled release : official journal of the Controlled Release Society

Vaccine using two glycolipids allows choice of delivery method to target lung tumor spreadDual-glycolipid engineered vaccine platform empowers delivery route customization to intercept tumor lung metastasis.

Article

3 weeks ago • Vaccine

A clade 2.3.4.4b HA mRNA vaccine may protect mice against different types of human H5N1 flu virusesCross-clade protection against human H5N1 isolates by a clade 2.3.4.4b HA mRNA vaccine in mice.

📖 Top 20% JournalArticle

3 weeks ago • Human vaccines & immunotherapeutics

Designed tiny particle vaccines for preventing and treating cancer and infectionsEngineered nanovaccines for prophylactic and therapeutic immunotherapy against cancer and infectious disease.

📖 Top 20% JournalArticle

3 weeks ago • Journal of controlled release : official journal of the Controlled Release Society

A nanomaterial that stays local to improve mRNA immune treatment without entering the bloodstreamA systemic-absorption-blocked (SEAL) nanoplatform for mRNA-based local immunotherapy.

Article

3 weeks ago • Antibody therapeutics

Llama mRNA-LNP vaccination allows quick isolation of specific nanobodies using cell-based selectionLlama mRNA-LNP immunization enables rapid isolation of target specific nanobodies using cell-based panning.

🎖️ Top 10% JournalArticle

3 weeks ago • Cell reports. Medicine

Improved liver healing by delivering mRNA to partly reprogram cells inside the bodyEnhanced liver regeneration via targeted mRNA delivery for partial in vivo reprogramming.

🥈 Top 2% JournalArticle

3 weeks ago • Frontiers in immunology

mRNA vaccine targeting a malaria surface protein produces versatile antibodiesTargeting a malaria merozoite surface protein with mRNA vaccine generates multifunctional antibodies.

🥉 Top 5% JournalArticle

3 weeks ago • Cell stem cell

Targeted gene editing of blood-forming stem cells inside the bodyEditing cells in place: Targeted in vivo gene editing of hematopoietic stem cells.

🥇 Top 1% JournalArticle

3 weeks ago • Technology in cancer research & treatment

Ultrasound-Activated Bionic Nanoparticles for Combined Therapy Against Medullary Thyroid CancerIn Vitro Investigation of LIFU-Triggered, Visualizable Bionic Nanoparticles for a "Three-In-One" Therapy Against Medullary Thyroid Carcinoma.

📖 Top 30% JournalArticle

3 weeks ago • Frontiers in genome editing

Using lysine-based lipid nanoparticles to improve delivery of large all-in-one CRISPR/Cas9 gene-editing toolsOvercoming delivery barriers of large all-in-one CRISPR/Cas9 plasmids using lysine-based lipid nanoparticles.

🎖️ Top 10% JournalArticle

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